1C2P

HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	RNA-DEPENDENT RNA POLYMERASE	polymer	576	64529.2	2	UniProt (P26663) Pfam (PF00998)	Hepatitis C virus
2	C, D (A, B)	water	water		18.0	725	Chemie (HOH)

Sequence modifications

A, B: 3 - 570 (UniProt: P26663)

PDB	External Database	Details
Ala -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
Mse 36	Met 2455	modified residue
Mse 71	Met 2490	modified residue
Mse 139	Met 2558	modified residue
Mse 173	Met 2592	modified residue
Mse 187	Met 2606	modified residue
Mse 215	Met 2634	modified residue
Mse 313	Met 2732	modified residue
Val 329	Thr 2748	conflict
Ala 338	Val 2757	conflict
Mse 343	Met 2762	modified residue
Mse 414	Met 2833	modified residue
Mse 423	Met 2842	modified residue
Mse 426	Met 2845	modified residue
Gln 544	Arg 2963	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	129058.3
All*	Total formula weight	129058.3

*Water molecules are not included.