1BJG
D221(169)N MUTANT DOES NOT PROMOTE OPENING OF THE COFACTOR IMIDAZOLIDINE RING
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDYLATE SYNTHASE | polymer | 264 | 30558.7 | 1 | UniProt (P0A884) Pfam (PF00303) | Escherichia coli | |
| 2 | B (A) | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE | non-polymer | 326.2 | 1 | Chemie (UFP) | |||
| 3 | C (A) | 5,10-METHYLENE-6-HYDROFOLIC ACID | non-polymer | 455.4 | 1 | Chemie (TMF) | |||
| 4 | D (A) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 2 - 264 (UniProt: P0A884)
| PDB | External Database | Details |
|---|---|---|
| Asn 169 | Asp 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30558.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 781.6 | |
| All* | Total formula weight | 31340.3 |
