1BI7
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CYCLIN-DEPENDENT KINASE 6 | polymer | 326 | 36987.3 | 1 | UniProt (Q00534) Pfam (PF00069) In PDB | Homo sapiens (human) | CDK6 |
| 2 | B | MULTIPLE TUMOR SUPPRESSOR | polymer | 156 | 16555.6 | 1 | UniProt (P42771) In PDB | Homo sapiens (human) | P16INK4A, MTS1 |
Sequence modifications
B: 1 - 156 (UniProt: P42771)
| PDB | External Database | Details |
|---|---|---|
| Asn 37 | Leu 37 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53542.9 | |
| All* | Total formula weight | 53542.9 |
