1A02
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (5'-D(*DTP*DTP*DGP*DGP*DAP*DAP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DCP*DAP*DTP*DAP*DG)-3') | polymer | 20 | 6178.0 | 1 | |||
| 2 | B (B) | DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3') | polymer | 20 | 6085.0 | 1 | |||
| 3 | C (N) | NUCLEAR FACTOR OF ACTIVATED T CELLS | polymer | 301 | 34270.9 | 1 | UniProt (Q13469) Pfam (PF00554) Pfam (PF16179) | Homo sapiens (human) | NFAT |
| 4 | D (F) | AP-1 FRAGMENT FOS | polymer | 56 | 6727.7 | 1 | UniProt (P01100) Pfam (PF00170) | Homo sapiens (human) | FOS |
| 5 | E (J) | AP-1 FRAGMENT JUN | polymer | 56 | 6583.8 | 1 | UniProt (P05412) Pfam (PF00170) | Homo sapiens (human) | JUN |
| 6 | F, G, H, I, J (A, B, N, F, J) | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence modifications
F: 138 - 193 (UniProt: P01100)
J: 263 - 318 (UniProt: P05412)
| PDB | External Database | Details |
|---|---|---|
| Met 138 | Glu 138 | engineered mutation |
| Ser 154 | Cys 154 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 263 | Ile 253 | engineered mutation |
| Ser 279 | Cys 269 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 59845.5 | |
| All* | Total formula weight | 59845.5 |
