1A02

STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006355	biological_process	regulation of DNA-templated transcription
F	0006357	biological_process	regulation of transcription by RNA polymerase II
J	0003677	molecular_function	DNA binding
J	0003700	molecular_function	DNA-binding transcription factor activity
J	0006355	biological_process	regulation of DNA-templated transcription
N	0003677	molecular_function	DNA binding
N	0003700	molecular_function	DNA-binding transcription factor activity
N	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00036
Number of Residues	15
Details	BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. Rre.RNKmAAAKsRNR

Chain	Residue	Details
F	ARG143-ARG157
J	ARG267-ARG282

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Necessary for synergistic transcriptional activity with SMAD3

Chain	Residue	Details
J	ARG282

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:11689449

Chain	Residue	Details
J	LYS281

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by PAK2 => ECO:0000269|PubMed:21177766

Chain	Residue	Details
J	THR296

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