11UE
Structure of PDGFRb Kinase Domain Bound to JNJ-PDGFRBi-1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Platelet-derived growth factor receptor beta | polymer | 429 | 48732.6 | 1 | UniProt (P09619) | Homo sapiens (human) | PDGF-R-beta,PDGFR-beta,Beta platelet-derived growth factor receptor,Beta-type platelet-derived growth factor receptor,CD140 antigen-like family member B,Platelet-derived growth factor receptor 1,PDGFR-1 |
| 2 | B (A) | N-[2-(2,2-dimethylpyrrolidin-1-yl)ethyl]-6-methyl-5-({1-methyl-6-[(1-methyl-1H-pyrazol-4-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}amino)pyridine-3-carboxamide | non-polymer | 503.6 | 1 | Chemie (A1DA1) PubChem (167444196) | |||
| 3 | C (A) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 557 - 981 (UniProt: P09619)
| PDB | External Database | Details |
|---|---|---|
| Gly 553 | - | expression tag |
| Ala 554 | - | expression tag |
| Met 555 | - | expression tag |
| Asp 556 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48732.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 503.6 | |
| All* | Total formula weight | 49236.2 |
