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3E20
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BU of 3e20 by Molmil
Crystal structure of S.pombe eRF1/eRF3 complex
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit, Eukaryotic peptide chain release factor subunit 1
Authors:Cheng, Z, Lim, M, Kong, C, Song, H.
Deposit date:2008-08-05
Release date:2009-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
5I4Q
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BU of 5i4q by Molmil
Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3)
Descriptor: CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ...
Authors:Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2016-02-12
Release date:2017-06-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
4LBY
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BU of 4lby by Molmil
Identifying ligand binding hot spots in proteins using brominated fragments
Descriptor: AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ...
Authors:Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P.
Deposit date:2013-06-21
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
6MIJ
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BU of 6mij by Molmil
Crystal structure of EF-Tu from Acinetobacter baumannii in complex with Mg2+ and GDP
Descriptor: Elongation factor Tu, FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-09-19
Release date:2018-10-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.955 Å)
Cite:To be published
To Be Published
1HA3
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BU of 1ha3 by Molmil
ELONGATION FACTOR TU IN COMPLEX WITH aurodox
Descriptor: BETA-MERCAPTOETHANOL, ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Vogeley, L, Palm, G.J, Mesters, J.R, Hilgenfeld, R.
Deposit date:2001-03-26
Release date:2001-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational Change of Elongation Factor TU Induced by Antibiotic Binding: Crystal Structure of the Complex between EF-TU:Gdp and Aurodox
J.Biol.Chem., 276, 2001
7O9K
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BU of 7o9k by Molmil
Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Valentin Gese, G, Hallberg, B.M.
Deposit date:2021-04-16
Release date:2021-06-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for late maturation steps of the human mitoribosomal large subunit.
Nat Commun, 12, 2021
6EZE
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BU of 6eze by Molmil
The open conformation of E.coli Elongation Factor Tu in complex with GDPNP.
Descriptor: DI(HYDROXYETHYL)ETHER, Elongation factor Tu 2, GLYCEROL, ...
Authors:Johansen, J.S, Blaise, M, Thirup, S.S.
Deposit date:2017-11-15
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form.
Nucleic Acids Res., 46, 2018
1QZD
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BU of 1qzd by Molmil
EF-Tu.kirromycin coordinates fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome
Descriptor: Elongation factor Tu
Authors:Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J.
Deposit date:2003-09-16
Release date:2003-11-04
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
8FR3
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BU of 8fr3 by Molmil
E. coli EF-Tu in complex with KKL-55
Descriptor: 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M.
Deposit date:2023-01-06
Release date:2023-09-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
3MMP
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BU of 3mmp by Molmil
Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins
Descriptor: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ...
Authors:Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R.
Deposit date:2010-04-20
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
1LS2
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BU of 1ls2 by Molmil
Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome
Descriptor: Elongation Factor Tu, Phenylalanine transfer RNA
Authors:Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
4CRN
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BU of 4crn by Molmil
Cryo-EM of a pretermination complex with eRF1 and eRF3
Descriptor: ERF1 IN RIBOSOME-BOUND ERF1-ERF3-GDPNP COMPLEX, ERF3 IN RIBOSOME BOUND ERF1-ERF3-GDPNP COMPLEX, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Preis, A, Heuer, A, Barrio-Garcia, C, Hauser, A, Eyler, D, Berninghausen, O, Green, R, Becker, T, Beckmann, R.
Deposit date:2014-02-28
Release date:2014-07-23
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing Erf1-Erf3 or Erf1-Abce1.
Cell Rep., 8, 2014
5LZW
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BU of 5lzw by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
4V5Q
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BU of 4v5q by Molmil
The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a near- cognate codon on the 70S ribosome
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V68
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BU of 4v68 by Molmil
T. thermophilus 70S ribosome in complex with mRNA, tRNAs and EF-Tu.GDP.kirromycin ternary complex, fitted to a 6.4 A Cryo-EM map.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Schuette, J.-C, Spahn, C.M.T.
Deposit date:2008-12-11
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Embo J., 28, 2009
5MI8
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BU of 5mi8 by Molmil
Structure of the phosphomimetic mutant of EF-Tu T383E
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
4Q7J
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BU of 4q7j by Molmil
Complex structure of viral RNA polymerase
Descriptor: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu 1, ...
Authors:Takeshita, D.
Deposit date:2014-04-25
Release date:2014-08-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular insights into replication initiation by Q beta replicase using ribosomal protein S1.
Nucleic Acids Res., 42, 2014
8G7Q
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BU of 8g7q by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
1AIP
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BU of 1aip by Molmil
EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
Descriptor: ELONGATION FACTOR TS, ELONGATION FACTOR TU
Authors:Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B.
Deposit date:1997-04-22
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
8G7P
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BU of 8g7p by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the cognate AUA codon (Structure I)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
4R71
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BU of 4r71 by Molmil
Structure of the Qbeta holoenzyme complex in the P1211 crystal form
Descriptor: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ...
Authors:Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R.
Deposit date:2014-08-26
Release date:2015-09-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural basis for RNA-genome recognition during bacteriophage Q beta replication.
Nucleic Acids Res., 43, 2015
4ZV4
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BU of 4zv4 by Molmil
Structure of Tse6 in complex with EF-Tu
Descriptor: Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Whitney, J.C, Sawai, S, Robinson, H, Mougous, J.D.
Deposit date:2015-05-18
Release date:2015-11-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.504 Å)
Cite:An Interbacterial NAD(P)(+) Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells.
Cell, 163, 2015
7PAK
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BU of 7pak by Molmil
70S ribosome with EF-Tu-tRNA and P-site tRNA in Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-30
Release date:2022-05-25
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PAJ
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BU of 7paj by Molmil
70S ribosome with EF-Tu-tRNA, P- and E-site tRNAs in Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-30
Release date:2022-05-25
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7A5G
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BU of 7a5g by Molmil
Structure of the elongating human mitoribosome bound to mtEF-Tu.GMPPCP and A/T mt-tRNA
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V.
Deposit date:2020-08-21
Release date:2020-12-23
Method:ELECTRON MICROSCOPY (4.33 Å)
Cite:Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020

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