2HCJ
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TRYPSIN-MODIFIED ELONGATION FACTOR TU IN COMPLEX WITH TETRACYCLINE
Descriptor:Protein chain elongation factor EF-Tu, MAGNESIUM ION, SULFATE ION, ...
Authors:Mui, S., Heffron, S.E., Aorora, A., Abel, K., Bergmann, E., Jurnak, F.
Deposit date:2006-06-16
Release date:2006-10-31
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
2HDN
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TRYPSIN-MODIFIED ELONGATION FACTOR TU IN COMPLEX WITH TETRACYCLINE AT 2.8 ANGSTROM RESOLUTION
Descriptor:Elongation factor EF-Tu, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Mui, S., Heffron, S.E., Aorora, A., Abel, K., Bergmann, E., Jurnak, F.
Deposit date:2006-06-20
Release date:2006-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
3E20
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CRYSTAL STRUCTURE OF S.POMBE ERF1/ERF3 COMPLEX
Descriptor:Eukaryotic peptide chain release factor GTP-binding subunit, Eukaryotic peptide chain release factor subunit 1
Authors:Cheng, Z., Lim, M., Kong, C., Song, H.
Deposit date:2008-08-05
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
5HXB
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CEREBLON IN COMPLEX WITH DDB1, CC-885, AND GSPT1
Descriptor:Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, DNA damage-binding protein 1, Protein cereblon, ...
Authors:Chamberlain, P.P., Matyskiela, M., Pagarigan, B.
Deposit date:2016-01-30
Release date:2016-06-29
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Nature, 535, 2016
5I4Q
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CONTACT-DEPENDENT INHIBITION SYSTEM FROM ESCHERICHIA COLI NC101 - TERNARY CDIA/CDII/EF-TU COMPLEX (DOMAINS 2 AND 3)
Descriptor:Contact-dependent inhibitor A, Contact-dependent inhibitor I, Elongation factor Tu, ...
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2016-02-12
Release date:2017-06-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
5I4R
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CONTACT-DEPENDENT INHIBITION SYSTEM FROM ESCHERICHIA COLI NC101 - TERNARY CDIA/CDII/EF-TU COMPLEX (TRYPSIN-MODIFIED)
Descriptor:Contact-dependent inhibitor A, Elongation factor Tu, Contact-dependent inhibitor I, ...
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2016-02-12
Release date:2017-06-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
1AIP
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EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
Descriptor:ELONGATION FACTOR TU, ELONGATION FACTOR TS
Authors:Wang, Y., Jiang, Y., Meyering-Voss, M., Sprinzl, M., Sigler, P.B.
Deposit date:1997-04-22
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
1B23
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E. COLI CYSTEINYL-TRNA AND T. AQUATICUS ELONGATION FACTOR EF-TU:GTP TERNARY COMPLEX
Descriptor:CYSTEINYL TRNA, ELONGATION FACTOR TU, MAGNESIUM ION, ...
Authors:Nissen, P., Kjeldgaard, M., Thirup, S., Nyborg, J.
Deposit date:1998-12-04
Release date:1998-12-07
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure Fold.Des., 7, 1999
1D2E
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CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP
Descriptor:ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Andersen, G.R., Thirup, S., Spremulli, L.L., Nyborg, J.
Deposit date:1999-09-23
Release date:1999-09-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
1D8T
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CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC
Descriptor:ELONGATION FACTOR TU, THIOCILLIN GE2270, MAGNESIUM ION, ...
Authors:Heffron, S.E., Jurnak, F.
Deposit date:1999-10-25
Release date:2000-10-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of an EF-TU Complex with a Thiazolyl Peptide Antibiotic Determined at 2.35 A Resolution: Atomic Basis for Ge2270A Inhibition of EF-TU.
Biochemistry, 39, 2000
1DG1
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WHOLE, UNMODIFIED, EF-TU(ELONGATION FACTOR TU).
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Abel, K., Yoder, M., Hilgenfeld, R., Jurnak, F.
Deposit date:1999-11-22
Release date:1999-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alpha to beta conformational switch in EF-Tu.
Structure, 4, 1996
1EFC
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INTACT ELONGATION FACTOR FROM E.COLI
Descriptor:PROTEIN (ELONGATION FACTOR), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Song, H., Parsons, M.R., Rowsell, S., Leonard, G., Phillips, S.E.V.
Deposit date:1998-11-24
Release date:1999-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution.
J.Mol.Biol., 285, 1999
1EFM
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STRUCTURE OF THE GDP DOMAIN OF EF-TU AND LOCATION OF THE AMINO ACIDS HOMOLOGOUS TO RAS ONCOGENE PROTEINS
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Jurnak, F.
Deposit date:1987-05-29
Release date:1987-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the GDP domain of EF-Tu and location of the amino acids homologous to ras oncogene proteins.
Science, 230, 1985
1EFT
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THE CRYSTAL STRUCTURE OF ELONGATION FACTOR EF-TU FROM THERMUS AQUATICUS IN THE GTP CONFORMATION
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Kjeldgaard, M., Nissen, P., Thirup, S., Nyborg, J.
Deposit date:1993-08-24
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation.
Structure, 1, 1993
1EFU
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ELONGATION FACTOR COMPLEX EF-TU/EF-TS FROM ESCHERICHIA COLI
Descriptor:ELONGATION FACTOR TU, ELONGATION FACTOR TS
Authors:Kawashima, T., Berthet-Colominas, C., Wulff, M., Cusack, S., Leberman, R.
Deposit date:1996-07-09
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution.
Nature, 379, 1996
1ETU
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STRUCTURAL DETAILS OF THE BINDING OF GUANOSINE DIPHOSPHATE TO ELONGATION FACTOR TU FROM E. COLI AS STUDIED BY X-RAY CRYSTALLOGRAPHY
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Clark, B.F.C., Lacour, T.F.M., Kjeldgaard, M., Morikawa, K., Nyborg, J., Rubin, R., Thirup, S.
Deposit date:1988-01-15
Release date:1988-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.
EMBO J., 4, 1985
1EXM
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP.
Descriptor:ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Hogg, T., Mesters, J.R., Hilgenfeld, R.
Deposit date:2000-05-03
Release date:2000-06-07
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Insights into the GTPase Mechanism of EF-Tu from Structural Studies
The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions, 28, 2000
1F60
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CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor:ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
Authors:Andersen, G.R., Pedersen, L., Valente, L., Kinzy, T.G., Nyborg, J.
Deposit date:2000-06-19
Release date:2000-07-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
1G7C
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YEAST EEF1A:EEF1BA IN COMPLEX WITH GDPNP
Descriptor:ELONGATION FACTOR 1-ALPHA, ELONGATION FACTOR 1-BETA, GUANOSINE-5'-MONOPHOSPHATE
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2000-11-10
Release date:2000-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1HA3
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ELONGATION FACTOR TU IN COMPLEX WITH AURODOX
Descriptor:ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Vogeley, L., Palm, G.J., Mesters, J.R., Hilgenfeld, R.
Deposit date:2001-03-26
Release date:2001-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational Change of Elongation Factor TU Induced by Antibiotic Binding: Crystal Structure of the Complex between EF-TU:Gdp and Aurodox
J.Biol.Chem., 276, 2001
1IJE
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NUCLEOTIDE EXCHANGE INTERMEDIATES IN THE EEF1A-EEF1BA COMPLEX
Descriptor:elongation factor 1-alpha, elongation factor 1-beta, GUANOSINE-5'-DIPHOSPHATE
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJF
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NUCLEOTIDE EXCHANGE MECHANISMS IN THE EEF1A-EEF1BA COMPLEX
Descriptor:elongation factor 1-alpha, elongation factor 1-beta, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1JNY
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CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS ELONGATION FACTOR 1 ALPHA IN COMPLEX WITH GDP
Descriptor:Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE
Authors:Vitagliano, L., Masullo, M., Sica, F., Zagari, A., Bocchini, V.
Deposit date:2001-07-26
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with GDP reveals novel features in nucleotide binding and exchange.
EMBO J., 20, 2001
1LS2
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FITTING OF EF-TU AND TRNA IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:Phenylalanine transfer RNA, Elongation Factor Tu
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1MJ1
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FITTING THE TERNARY COMPLEX OF EF-TU/TRNA/GTP AND RIBOSOMAL PROTEINS INTO A 13 A CRYO-EM MAP OF THE COLI 70S RIBOSOME
Descriptor:Phe-tRNA, sarcin-ricin loop of 23SrRNA, helix 69 of 23S rRNA, ...
Authors:Stark, H., Rodnina, M.V., Wieden, H.-J., Zemlin, F., Wintermeyer, W., Vanheel, M.
Deposit date:2002-08-26
Release date:2002-11-01
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Ribosome Interactions of Aminoacyl-tRNA and Elongation Factor TU in the Codon Recognition Complex
Nat.Struct.Biol., 9, 2002
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