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2V76
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BU of 2v76 by Molmil
Crystal structure of the human dok1 PTB domain
Descriptor: 1,2-ETHANEDIOL, DOCKING PROTEIN 1, GLYCEROL, ...
Authors:Oxley, C.L, Anthis, N.J, Lowe, E.D, Campbell, I.D, Wegener, K.L.
Deposit date:2007-07-26
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An Integrin Phosphorylation Switch: The Effect of {Beta}3 Integrin Tail Phosphorylation on Dok1 and Talin Binding.
J.Biol.Chem., 283, 2008
1MIX
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BU of 1mix by Molmil
Crystal structure of a FERM domain of Talin
Descriptor: Talin
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
5U1M
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BU of 5u1m by Molmil
Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor
Descriptor: Insulin receptor, Insulin receptor substrate 1
Authors:Eck, M.J, Dhe-Paganon, S.
Deposit date:2016-11-28
Release date:2017-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression.
Nat Commun, 8, 2017
5XBF
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BU of 5xbf by Molmil
Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3
Descriptor: ACETATE ION, D-MALATE, GLYCEROL, ...
Authors:Li, J, He, Y, Weck, W.L, Lu, Q, Tyska, M.J, Zhang, M.
Deposit date:2017-03-17
Release date:2017-05-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5MV8
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BU of 5mv8 by Molmil
Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain
Descriptor: GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ...
Authors:Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A.
Deposit date:2017-01-16
Release date:2017-07-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Myosin 7 and its adaptors link cadherins to actin.
Nat Commun, 8, 2017
8FSE
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BU of 8fse by Molmil
Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain
Descriptor: Integrin beta-2,Talin-1
Authors:Wu, J, Gao, T.
Deposit date:2023-01-09
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024
1MIZ
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BU of 1miz by Molmil
Crystal structure of an integrin beta3-talin chimera
Descriptor: TALIN, integrin beta3
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
3IVF
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BU of 3ivf by Molmil
Crystal structure of the talin head FERM domain
Descriptor: Talin-1
Authors:Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-09-01
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
8FTB
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BU of 8ftb by Molmil
Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with a K306Q mutation
Descriptor: Integrin beta-2,Talin-1
Authors:Wu, J, Gao, T.
Deposit date:2023-01-11
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024
5EJR
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BU of 5ejr by Molmil
Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain
Descriptor: 1,2-ETHANEDIOL, Myosin-I heavy chain
Authors:Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Clause, J, Titus, M.A, Houdusse, A.
Deposit date:2015-11-02
Release date:2016-07-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Myosin MyTH4-FERM structures highlight important principles of convergent evolution.
Proc.Natl.Acad.Sci.USA, 113, 2016
4F7G
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BU of 4f7g by Molmil
Crystal structure of talin autoinhibition complex
Descriptor: Talin-1
Authors:Song, X, Qin, J, Ye, S, Zhang, R.
Deposit date:2012-05-16
Release date:2012-07-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
Cell Res., 22, 2012
3G9W
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BU of 3g9w by Molmil
Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ...
Authors:Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
1MK7
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BU of 1mk7 by Molmil
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1QQG
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BU of 1qqg by Molmil
CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1
Descriptor: INSULIN RECEPTOR SUBSTRATE 1
Authors:Dhe-Paganon, S, Shoelson, S.E.
Deposit date:1999-06-04
Release date:1999-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
Proc.Natl.Acad.Sci.USA, 96, 1999
1P5T
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BU of 1p5t by Molmil
Crystal Structure of Dok1 PTB Domain
Descriptor: Docking protein 1
Authors:Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yuan, J, Rao, Z.
Deposit date:2003-04-28
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.BIOL.CHEM., 279, 2004
5MV7
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BU of 5mv7 by Molmil
Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain
Descriptor: SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb
Authors:Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A.
Deposit date:2017-01-15
Release date:2017-07-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Myosin 7 and its adaptors link cadherins to actin.
Nat Commun, 8, 2017
1J0W
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BU of 1j0w by Molmil
Crystal Structure Analysis of the Dok-5 PTB Domain
Descriptor: downstream of tyrosine kinase 5
Authors:Shi, N, Ding, Y, Qiang, B.Q, Yuan, J.G, Rao, Z.H.
Deposit date:2002-11-25
Release date:2003-12-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of the Dok-5 PTB Domain
To be Published
1UEF
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BU of 1uef by Molmil
Crystal Structure of Dok1 PTB Domain Complex
Descriptor: 13-mer peptide from Proto-oncogene tyrosine-protein kinase receptor ret, Docking protein 1
Authors:Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yan, J, Rao, Z.
Deposit date:2003-05-14
Release date:2004-05-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.Biol.Chem., 279, 2004
6U4K
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BU of 6u4k by Molmil
Human talin2 residues 1-403
Descriptor: Talin-2
Authors:Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K.
Deposit date:2019-08-26
Release date:2020-07-08
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (2.555 Å)
Cite:A distinct talin2 structure directs isoform specificity in cell adhesion.
J.Biol.Chem., 295, 2020
5MV9
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BU of 5mv9 by Molmil
Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain
Descriptor: ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ...
Authors:Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A.
Deposit date:2017-01-16
Release date:2017-07-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Myosin 7 and its adaptors link cadherins to actin.
Nat Commun, 8, 2017
3ML4
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BU of 3ml4 by Molmil
Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region
Descriptor: Muscle, skeletal receptor tyrosine-protein kinase, Protein Dok-7
Authors:Bergamin, E, Hubbard, S.R.
Deposit date:2010-04-16
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization.
Mol.Cell, 39, 2010
1Y19
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BU of 1y19 by Molmil
Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
5EJS
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BU of 5ejs by Molmil
Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain, mutant 1
Descriptor: Myosin-I heavy chain
Authors:Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A.
Deposit date:2015-11-02
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Myosin MyTH4-FERM structures highlight important principles of convergent evolution.
Proc.Natl.Acad.Sci.USA, 113, 2016
8T0D
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BU of 8t0d by Molmil
Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation
Descriptor: Integrin beta-2,Talin-1
Authors:Wu, J, Gao, T.
Deposit date:2023-05-31
Release date:2024-07-03
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024
6VGU
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BU of 6vgu by Molmil
Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin
Descriptor: Integrin beta-3,Talin-1
Authors:Zhang, P, Sun, Y, Wu, J.
Deposit date:2020-01-09
Release date:2020-12-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.
Proc.Natl.Acad.Sci.USA, 117, 2020

 

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數據於2024-09-18公開中

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