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6LCJ
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BU of 6lcj by Molmil
TtGalA, alpha-galactosidase from Thermus thermopilus in apo form
Descriptor: Alpha-galactosidase
Authors:Chen, S.C, Hsu, C.H.
Deposit date:2019-11-19
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of alpha-Galactosidase fromThermus thermophilus: Insight into Hexamer Assembly and Substrate Specificity.
J.Agric.Food Chem., 68, 2020
6LCL
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BU of 6lcl by Molmil
TtGalA, alpha-galactosidase from Thermus thermophilus in complex with stachyose
Descriptor: Alpha-galactosidase, alpha-D-galactopyranose-(1-6)-alpha-D-galactopyranose
Authors:Chen, S.C, Hsu, C.H.
Deposit date:2019-11-19
Release date:2020-09-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of alpha-Galactosidase from Thermus thermophilus : Insight into Hexamer Assembly and Substrate Specificity.
J.Agric.Food Chem., 68, 2020
6LCK
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BU of 6lck by Molmil
TtGalA, alpha-galactosidase from Thermus thermophilus in complex with p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG)
Descriptor: 4-nitrophenyl alpha-D-galactopyranoside, Alpha-galactosidase
Authors:Chen, S.C, Hsu, C.H.
Deposit date:2019-11-19
Release date:2020-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of alpha-Galactosidase fromThermus thermophilus: Insight into Hexamer Assembly and Substrate Specificity.
J.Agric.Food Chem., 68, 2020
9AWT
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BU of 9awt by Molmil
Structure of the A type blood alpha-D-galactosamine galactosaminidase from Flavonifractor plautii in complex with GalN-pNP
Descriptor: 4-nitrophenyl 2-amino-2-deoxy-alpha-D-galactopyranoside, A type blood alpha-D-galactosamine galactosaminidase, CHLORIDE ION, ...
Authors:Worrall, L.J, Strynadka, N.C.J.
Deposit date:2024-03-05
Release date:2024-12-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cobalt as a Cofactor for alpha-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens
Acs Catalysis, 2024
9AYU
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BU of 9ayu by Molmil
Structure of the A type blood alpha-D-galactosamine galactosaminidase D463A mutant from Flavonifractor plautii
Descriptor: 1,2-ETHANEDIOL, A type blood alpha-D-galactosamine galactosaminidase, CHLORIDE ION, ...
Authors:Worrall, L.J, Strynadka, N.C.J.
Deposit date:2024-03-08
Release date:2024-12-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cobalt as a Cofactor for alpha-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens
Acs Catalysis, 2024
9AY8
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BU of 9ay8 by Molmil
Structure of the A type blood alpha-D-galactosamine galactosaminidase from Flavonifractor plautii
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, A type blood alpha-D-galactosamine galactosaminidase, CHLORIDE ION, ...
Authors:Worrall, L.J, Strynadka, N.C.J.
Deposit date:2024-03-07
Release date:2024-12-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cobalt as a Cofactor for alpha-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens
Acs Catalysis, 2024
3MI6
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BU of 3mi6 by Molmil
Crystal structure of the alpha-galactosidase from Lactobacillus brevis, Northeast Structural Genomics Consortium Target LbR11.
Descriptor: Alpha-galactosidase
Authors:Vorobiev, S, Chen, Y, Seetharaman, J, Belote, R, Sahdev, S, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-04-09
Release date:2010-04-28
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Crystal structure of the alpha-galactosidase from Lactobacillus brevis.
To be Published
2YFN
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BU of 2yfn by Molmil
galactosidase domain of alpha-galactosidase-sucrose kinase, AgaSK
Descriptor: 1,2-ETHANEDIOL, ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK, GLYCEROL, ...
Authors:Sulzenbacher, G, Bruel, L, Tison-Cervera, M, Pujol, A, Nicoletti, C, Perrier, J, Galinier, A, Ropartz, D, Fons, M, Pompeo, F, Giardina, T.
Deposit date:2011-04-07
Release date:2011-09-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Agask, a Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities
J.Biol.Chem., 286, 2011
6JHP
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BU of 6jhp by Molmil
Crystal structure of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-galactosidase
Authors:Liu, Y, Huang, P, Ma, J, Jiang, Z.
Deposit date:2019-02-18
Release date:2020-05-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.559 Å)
Cite:Crystal structure and phylogenetic analysis of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila
To be published
1ZY9
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BU of 1zy9 by Molmil
Crystal structure of Alpha-galactosidase (EC 3.2.1.22) (Melibiase) (tm1192) from Thermotoga maritima at 2.34 A resolution
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, alpha-galactosidase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2005-06-09
Release date:2005-07-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of alpha-galactosidase (ec 3.2.1.22) (melibiase) (tm1192) from Thermotoga maritima at 2.34 A resolution
to be published
8K7U
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BU of 8k7u by Molmil
the alpha-galactosidase 5 with Cacl2
Descriptor: Alpha-galactosidase
Authors:Li, Y.W, Ru, Y.X.
Deposit date:2023-07-27
Release date:2024-07-31
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Activity-based metaproteomics driven discovery and enzymological characterization of potential alpha-galactosidases in the mouse gut microbiome.
Commun Chem, 7, 2024
8K7V
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BU of 8k7v by Molmil
the alpha-galactosidase 5 with inhibitor ABP2
Descriptor: 8-azido-1-((1S,2S,3S,4S,5R,6S)-2,3,4-trihydroxy-5-(hydroxymethyl)-7-azabicyclo[4.1.0]heptan-7-yl)octan-1-one, Alpha-galactosidase
Authors:Li, Y.W, Ru, Y.X.
Deposit date:2023-07-27
Release date:2024-07-31
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Activity-based metaproteomics driven discovery and enzymological characterization of potential alpha-galactosidases in the mouse gut microbiome.
Commun Chem, 7, 2024
8K1A
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BU of 8k1a by Molmil
the wild-typed alpha-galactosidase 5
Descriptor: Alpha-galactosidase
Authors:Li, Y.W, Ru, Y.X.
Deposit date:2023-07-10
Release date:2024-07-17
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Activity-based metaproteomics driven discovery and enzymological characterization of potential alpha-galactosidases in the mouse gut microbiome.
Commun Chem, 7, 2024
2XN2
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BU of 2xn2 by Molmil
Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM with galactose
Descriptor: ALPHA-GALACTOSIDASE, GLYCEROL, IMIDAZOLE, ...
Authors:Fredslund, F, Abou Hachem, M, Larsen, R.J, Sorensen, P.G, Lo Leggio, L, Svensson, B.
Deposit date:2010-07-30
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding.
J.Mol.Biol., 412, 2011
2XN1
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BU of 2xn1 by Molmil
Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM with TRIS
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-GALACTOSIDASE, GLYCEROL
Authors:Fredslund, F, Abou Hachem, M, Larsen, R.J, Sorensen, P.G, Lo Leggio, L, Svensson, B.
Deposit date:2010-07-30
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding.
J.Mol.Biol., 412, 2011
5M16
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BU of 5m16 by Molmil
Structure of GH36 alpha-galactosidase from Thermotoga maritima in complex with a hydrolysed cyclopropyl carbasugar.
Descriptor: (1~{R},2~{S},3~{S},4~{S},5~{S},6~{S})-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3,4,5-tetrol, Alpha-galactosidase, MAGNESIUM ION, ...
Authors:Pengelly, R, Gloster, T.
Deposit date:2016-10-07
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
5M1I
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BU of 5m1i by Molmil
Structure of GH36 alpha-galactosidase from Thermotoga maritima in a covalent complex with a cyclopropyl carbasugar.
Descriptor: (1~{R},2~{S},3~{S},4~{S},6~{R})-4-fluoranyl-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3-diol, 1,2-ETHANEDIOL, Alpha-galactosidase, ...
Authors:Pengelly, R, Gloster, T.
Deposit date:2016-10-07
Release date:2016-11-09
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
2XN0
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BU of 2xn0 by Molmil
Structure of alpha-galactosidase from Lactobacillus acidophilus NCFM, PtCl4 derivative
Descriptor: ALPHA-GALACTOSIDASE, GLYCEROL, PLATINUM (II) ION
Authors:Fredslund, F, Abou Hachem, M, Larsen, R.J, Sorensen, P.G, Lo Leggio, L, Svensson, B.
Deposit date:2010-07-30
Release date:2011-08-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding.
J.Mol.Biol., 412, 2011
5M12
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BU of 5m12 by Molmil
Structure of GH36 alpha-galactosidase from Thermotoga maritima in complex with intact cyclopropyl-carbasugar.
Descriptor: (1~{R},2~{S},3~{S},4~{R},5~{S},6~{S})-5-[3,5-bis(fluoranyl)phenoxy]-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3,4-triol, Alpha-galactosidase, MAGNESIUM ION, ...
Authors:Pengelly, R, Gloster, T.
Deposit date:2016-10-07
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
5M0X
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BU of 5m0x by Molmil
Structure of apo structure of GH36 alpha-galactosidase from Thermotoga maritima
Descriptor: Alpha-galactosidase, MAGNESIUM ION, SULFATE ION
Authors:Pengelly, R, Gloster, T.
Deposit date:2016-10-06
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Angew.Chem.Int.Ed.Engl., 55, 2016
2YFO
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BU of 2yfo by Molmil
GALACTOSIDASE DOMAIN OF ALPHA-GALACTOSIDASE-SUCROSE KINASE, AGASK, in complex with galactose
Descriptor: ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK, GLYCEROL, PHOSPHATE ION, ...
Authors:Sulzenbacher, G, Bruel, L, Tison-Cervera, M, Pujol, A, Nicoletti, C, Perrier, J, Galinier, A, Ropartz, D, Fons, M, Pompeo, F, Giardina, T.
Deposit date:2011-04-07
Release date:2011-09-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Agask, a Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities
J.Biol.Chem., 286, 2011
6GWG
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BU of 6gwg by Molmil
Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose covalently linked to the nucleophile
Descriptor: (1~{S},2~{S},3~{S})-3-fluoranyl-6-(hydroxymethyl)cyclohex-5-ene-1,2,4-triol, Alpha-galactosidase, GLYCEROL, ...
Authors:Gloster, T.M, Oehler, V.
Deposit date:2018-06-24
Release date:2018-08-22
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
6GVD
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BU of 6gvd by Molmil
Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose
Descriptor: (1~{S},2~{S},3~{S},4~{S})-5-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, Alpha-galactosidase, MAGNESIUM ION, ...
Authors:Gloster, T.M, Pengelly, R.J.
Deposit date:2018-06-20
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
6GWF
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BU of 6gwf by Molmil
Alpha-galactosidase mutant D387A from Thermotoga maritima in complex with intact cyclohexene-based carbasugar mimic of galactose with 2,4-dinitro leaving group
Descriptor: (1~{S},2~{S},5~{S},6~{R})-5-(2,4-dinitrophenoxy)-6-fluoranyl-3-(hydroxymethyl)cyclohex-3-ene-1,2-diol, Alpha-galactosidase, MAGNESIUM ION, ...
Authors:Gloster, T.M, Oehler, V.
Deposit date:2018-06-24
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018
6GTA
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BU of 6gta by Molmil
Alpha-galactosidase mutant D378A from Thermotoga maritima in complex with intact cyclohexene-based carbasugar mimic of galactose with 3,5 difluorophenyl leaving group
Descriptor: (1~{R},2~{S},3~{S},6~{S})-6-[3,5-bis(fluoranyl)phenoxy]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol, Alpha-galactosidase, MAGNESIUM ION, ...
Authors:Gloster, T.M, Pengelly, R.J.
Deposit date:2018-06-17
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Nat Commun, 9, 2018

 

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