2YZS
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CRYSTAL STRUCTURE OF UNCHARACTERIZED CONSERVED PROTEIN FROM AQUIFEX AEOLICUS
Descriptor:Putative uncharacterized protein, SULFATE ION
Authors:Ebihara, A., Yokoyama, S., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-06
Release date:2007-11-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of uncharacterized conserved protein from Aquifex aeolicus
To be Published
3GOD
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STRUCTURAL BASIS FOR DNASE ACTIVITY OF A CONSERVED PROTEIN IMPLICATED IN CRISPR-MEDIATED ANTIVIRAL DEFENSE
Descriptor:Cas1, MANGANESE (II) ION, SODIUM ION, ...
Authors:Wiedenheft, B.
Deposit date:2009-03-18
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural Basis for DNase Activity of a Conserved Protein Implicated in CRISPR-Mediated Genome Defense.
Structure, 17, 2009
3NKD
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STRUCTURE OF CRISP-ASSOCIATED PROTEIN CAS1 FROM ESCHERICHIA COLI STR. K-12
Descriptor:CRISPR-associated protein Cas1
Authors:Nocek, B., Skarina, T., Beloglazova, N., Savchenko, A., Joachimiak, A., Yakunin, A.
Deposit date:2010-06-18
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.
Mol.Microbiol., 79, 2011
3NKE
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HIGH RESOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN CRISP-ASSOCIATED PROTEIN CAS1 FROM ESCHERICHIA COLI STR. K-12
Descriptor:protein ygbT, 1,2-ETHANEDIOL, SULFITE ION, ...
Authors:Nocek, B., Skarina, T., Beloglazova, N., Savchenko, A., Joachimiak, A., Yakunin, A.
Deposit date:2010-06-18
Release date:2010-08-25
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.
Mol.Microbiol., 79, 2011
4N06
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CRYSTAL STRUCTURE OF CAS1 FROM ARCHAEOGLOBUS FULGIDUS AND ITS NUCLEOLYTIC ACTIVITY
Descriptor:CRISPR-associated endonuclease Cas1 1
Authors:Kim, T.Y., Shin, M., Yen, L.H.T., Kim, J.S.
Deposit date:2013-10-01
Release date:2014-01-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Cas1 from Archaeoglobus fulgidus and characterization of its nucleolytic activity
Biochem.Biophys.Res.Commun., 441, 2013
4W8K
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CRYSTAL STRUCTURE OF A PUTATIVE CAS1 ENZYME FROM VIBRIO PHAGE ICP1
Descriptor:Cas1 protein, POTASSIUM ION
Authors:Stogios, P.J., Wawrzak, Z., Onopriyeno, O., Yim, V., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-08-25
Release date:2014-09-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:To be published
To Be Published
4WJ0
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STRUCTURE OF PH1245, A CAS1 FROM PYROCOCCUS HORIKOSHII
Descriptor:CRISPR-associated endonuclease Cas1, CHLORIDE ION
Authors:Petit, P., Brown, G., Savchenko, A., Yakunin, A.F.
Deposit date:2014-09-29
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of PH1245, a cas1 from Pyrococcus horikoshii
To Be Published
4XTK
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STRUCTURE OF TM1797, A CAS1 PROTEIN FROM THERMOTOGA MARITIMA
Descriptor:CRISPR-associated endonuclease Cas1
Authors:Petit, P., Beloglazova, N., Skarina, T., Chang, C., Edwards, A., Joachimiak, A., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2015-01-23
Release date:2015-02-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and nuclease activity of tm1797, a cas1 protein from thermotoga maritima
To Be Published
4ZKJ
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CRYSTAL STRUCTURE OF CRISPR-ASSOCIATED PROTEIN
Descriptor:CRISPR-associated protein Cas1, GLYCEROL
Authors:Ka, D., Bae, E.
Deposit date:2015-04-30
Release date:2016-01-13
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Streptococcus pyogenes Cas1 and Its Interaction with Csn2 in the Type II CRISPR-Cas System
Structure, 24, 2016
5DLJ
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CRYSTAL STRUCTURE OF CAS-DNA-N1 COMPLEX
Descriptor:CRISPR-associated endonuclease Cas1, 39-mer DNA N1-F, 39-mer DNA N1-R, ...
Authors:Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
Deposit date:2015-09-05
Release date:2015-11-11
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5FCL
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CRYSTAL STRUCTURE OF CAS1 FROM PECTOBACTERIUM ATROSEPTICUM
Descriptor:CRISPR-associated endonuclease Cas1
Authors:Wilkinson, M.E., Nakatani, Y., Opel-Reading, H.K., Fineran, P.C., Krause, K.L.
Deposit date:2015-12-15
Release date:2016-03-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system.
Biochem.J., 473, 2016
4QDL
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CRYSTAL STRUCTURE OF E.COLI CAS1-CAS2 COMPLEX
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2
Authors:Tamulaitiene, G., Sinkunas, T., Silanskas, A., Gasiunas, G., Grazulis, S., Siksnys, V.
Deposit date:2014-05-14
Release date:2014-05-28
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of E.coli Cas1-Cas2 complex
To be Published
5DQT
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CRYSTAL STRUCTURE OF CAS-DNA-22 COMPLEX
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (34-MER), ...
Authors:Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
Deposit date:2015-09-15
Release date:2015-11-11
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5DQU
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CRYSTAL STRUCTURE OF CAS-DNA-10 COMPLEX
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*TP*TP*TP*T)-3'), ...
Authors:Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
Deposit date:2015-09-15
Release date:2015-11-11
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5DQZ
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CRYSTAL STRUCTURE OF CAS-DNA-PAM COMPLEX
Descriptor:CRISPR-associated endonuclease Cas1, DNA (36-MER), CRISPR-associated endoribonuclease Cas2, ...
Authors:Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
Deposit date:2015-09-15
Release date:2015-11-11
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5DS4
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CRYSTAL STRUCTURE THE ESCHERICHIA COLI CAS1-CAS2 COMPLEX BOUND TO PROTOSPACER DNA
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER)
Authors:Nunez, J.K., Harrington, L.B., Kranzusch, P.J., Engelman, A.N., Doudna, J.A.
Deposit date:2015-09-16
Release date:2015-10-28
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nature, 527, 2015
5DS5
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CRYSTAL STRUCTURE THE ESCHERICHIA COLI CAS1-CAS2 COMPLEX BOUND TO PROTOSPACER DNA AND MG
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ...
Authors:Nunez, J.K., Harrington, L.B., Kranzusch, P.J., Engelman, A.N., Doudna, J.A.
Deposit date:2015-09-16
Release date:2015-10-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nature, 527, 2015
5DS6
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CRYSTAL STRUCTURE THE ESCHERICHIA COLI CAS1-CAS2 COMPLEX BOUND TO PROTOSPACER DNA WITH SPLAYED ENDS
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (29-MER), ...
Authors:Nunez, J.K., Harrington, L.B., Kranzusch, P.J., Engelman, A.N., Doudna, J.A.
Deposit date:2015-09-16
Release date:2015-10-28
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.352 Å)
Cite:Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nature, 527, 2015
5VVJ
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CAS1-CAS2 BOUND TO HALF-SITE INTERMEDIATE
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ...
Authors:Wright, A.V., Knott, G.J., Doxzen, K.W., Doudna, J.A.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5VVK
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CAS1-CAS2 BOUND TO FULL-SITE MIMIC
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*CP*CP*CP*CP*AP*GP*TP*AP*GP*C)-3'), ...
Authors:Wright, A.V., Knott, G.J., Doxzen, K.D., Doudna, J.A.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5VVL
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CAS1-CAS2 BOUND TO FULL-SITE MIMIC WITH NI
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (11-MER), ...
Authors:Wright, A.V., Knott, G.J., Doxzen, K.D., Doudna, J.A.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5WFE
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CAS1-CAS2-IHF-DNA HOLO-COMPLEX
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ...
Authors:Wright, A.V., Liu, J.J., Nogales, E., Doudna, J.A.
Deposit date:2017-07-11
Release date:2017-08-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5XVN
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E. FAR CAS1-CAS2/PRESPACER BINARY COMPLEX
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ...
Authors:Xiao, Y., Ng, S., Nam, K.H., Ke, A.
Deposit date:2017-06-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
5XVO
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E. FAE CAS1-CAS2/PRESPACER/TARGET TERNARY COMPLEX REVEALING DNA SAMPLING AND HALF-INTEGRATION STATES
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ...
Authors:Xiao, Y., Ng, S., Nam, K.H., Ke, A.
Deposit date:2017-06-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
5XVP
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E. FAE CAS1-CAS2/PRESPACER/TARGET TERNARY COMPLEX REVEALING THE FULLY INTEGRATED STATES
Descriptor:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (73-MER), ...
Authors:Xiao, Y., Ng, S., Nam, K.H., Ke, A.
Deposit date:2017-06-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
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