2YZS
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3GOD
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4W8K
| Crystal structure of a putative Cas1 enzyme from Vibrio phage ICP1 | Descriptor: | Cas1 protein, POTASSIUM ION | Authors: | Stogios, P.J, Wawrzak, Z, Onopriyeno, O, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-08-25 | Release date: | 2014-09-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | To be published To Be Published
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4XTK
| Structure of TM1797, a CAS1 protein from Thermotoga maritima | Descriptor: | CRISPR-associated endonuclease Cas1 | Authors: | Petit, P, Beloglazova, N, Skarina, T, Chang, C, Edwards, A, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-01-23 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and nuclease activity of tm1797, a cas1 protein from thermotoga maritima To Be Published
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4WJ0
| Structure of PH1245, a cas1 from Pyrococcus horikoshii | Descriptor: | CHLORIDE ION, CRISPR-associated endonuclease Cas1 | Authors: | Petit, P, Brown, G, Savchenko, A, Yakunin, A.F. | Deposit date: | 2014-09-29 | Release date: | 2014-10-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure of PH1245, a cas1 from Pyrococcus horikoshii To Be Published
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6OPM
| Casposase bound to integration product | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, DNA 21-mer, ... | Authors: | Dyda, F, Hickman, A.B, Kailasan, S. | Deposit date: | 2019-04-25 | Release date: | 2020-02-12 | Last modified: | 2020-08-26 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas. Elife, 9, 2020
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6KE1
| Crystal structure of TtCas1 | Descriptor: | CRISPR-associated endonuclease Cas1 2 | Authors: | Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y. | Deposit date: | 2019-07-03 | Release date: | 2019-12-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Crystal structure of Cas1 in complex with branched DNA. Sci China Life Sci, 63, 2020
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4N06
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3NKD
| Structure of CRISP-associated protein Cas1 from Escherichia coli str. K-12 | Descriptor: | CRISPR-associated protein Cas1 | Authors: | Nocek, B, Skarina, T, Beloglazova, N, Savchenko, A, Joachimiak, A, Yakunin, A. | Deposit date: | 2010-06-18 | Release date: | 2010-08-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol.Microbiol., 79, 2011
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3NKE
| High resolution structure of the C-terminal domain CRISP-associated protein Cas1 from Escherichia coli str. K-12 | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, SULFITE ION, ... | Authors: | Nocek, B, Skarina, T, Beloglazova, N, Savchenko, A, Joachimiak, A, Yakunin, A. | Deposit date: | 2010-06-18 | Release date: | 2010-08-25 | Last modified: | 2014-12-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol.Microbiol., 79, 2011
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6KDV
| Crystal structure of TtCas1-DNA complex | Descriptor: | CRISPR-associated endonuclease Cas1 2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*GP*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*AP*GP*CP*AP*TP*CP*GP*AP*CP*TP*C)-3') | Authors: | Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y. | Deposit date: | 2019-07-02 | Release date: | 2019-12-18 | Last modified: | 2020-05-06 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Crystal structure of Cas1 in complex with branched DNA. Sci China Life Sci, 63, 2020
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8K25
| Structure of Cas1-Cas2-dsDNA complex | Descriptor: | Cas1, DNA (5'-D(P*CP*AP*AP*TP*TP*TP*AP*AP*AP*TP*AP*GP*GP*GP*AP*AP*G)-3'), DNA (5'-D(P*TP*TP*CP*CP*CP*TP*AP*TP*TP*TP*AP*AP*AP*TP*TP*GP*C)-3'), ... | Authors: | Zhang, L.X, Feng, Y. | Deposit date: | 2023-07-12 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of Cas1-Cas2 complex bound dsDNA To Be Published
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8K21
| Cas1-Cas2-dsDNA subregion in ICP1 Csy-DNA-Cas1-2/3 complex | Descriptor: | Cas1, DNA (5'-D(*AP*TP*CP*TP*TP*CP*CP*CP*TP*AP*TP*TP*TP*AP*AP*AP*TP*TP*GP*CP*T)-3'), DNA (5'-D(P*AP*GP*CP*AP*AP*TP*TP*TP*AP*AP*AP*TP*AP*GP*GP*GP*AP*AP*GP*AP*T)-3'), ... | Authors: | Zhang, L.X, Feng, Y. | Deposit date: | 2023-07-12 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of csy complex with short DNA To Be Published
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8K26
| Structure of Cas1-Cas2 complex | Descriptor: | Cas1, HD Cas3-type domain-containing protein | Authors: | Zhang, L.X, Feng, Y. | Deposit date: | 2023-07-12 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of csy complex with short DNA To Be Published
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5FCL
| Crystal structure of Cas1 from Pectobacterium atrosepticum | Descriptor: | CRISPR-associated endonuclease Cas1 | Authors: | Wilkinson, M.E, Nakatani, Y, Opel-Reading, H.K, Fineran, P.C, Krause, K.L. | Deposit date: | 2015-12-15 | Release date: | 2016-03-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system. Biochem.J., 473, 2016
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4QDL
| Crystal structure of E.coli Cas1-Cas2 complex | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 | Authors: | Tamulaitiene, G, Sinkunas, T, Silanskas, A, Gasiunas, G, Grazulis, S, Siksnys, V. | Deposit date: | 2014-05-14 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of E.coli Cas1-Cas2 complex To be Published
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4P6I
| Crystal structure of the Cas1-Cas2 complex from Escherichia coli | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 | Authors: | Nunez, J.K, Kranzusch, P.J, Noeske, J, Doudna, J.A. | Deposit date: | 2014-03-24 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity. Nat.Struct.Mol.Biol., 21, 2014
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7CR6
| Synechocystis Cas1-Cas2/prespacer binary complex | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 1, DNA (36-MER) | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2020-08-12 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.72 Å) | Cite: | Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis. Nucleic Acids Res., 49, 2021
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7CR8
| Synechocystis Cas1-Cas2-prespacerL complex | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 1, DNA (36-MER) | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2020-08-12 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis. Nucleic Acids Res., 49, 2021
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6QXT
| Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-08 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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6QY3
| Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-08 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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6QXF
| Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-07 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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7EI1
| Structure of Pyrococcus furiosus Cas1Cas2 complex | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2021-03-30 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | A distinct structure of Cas1-Cas2 complex provides insights into the mechanism for the longer spacer acquisition in Pyrococcus furiosus. Int.J.Biol.Macromol., 183, 2021
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8D3Q
| Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... | Authors: | Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. | Deposit date: | 2022-06-01 | Release date: | 2022-11-02 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Mol.Cell, 82, 2022
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8D3M
| Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/Processed prespacer | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... | Authors: | Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. | Deposit date: | 2022-06-01 | Release date: | 2022-11-02 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Mol.Cell, 82, 2022
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