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8PSP
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BU of 8psp by Molmil
Asymmetric unit of the yeast fatty acid synthase in rotated state with ACP at the acetyl transferase domain (FASx sample)
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PSM
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BU of 8psm by Molmil
Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the malonyl/palmitoyl transferase domain (FASx sample)
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PSL
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BU of 8psl by Molmil
Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the ketosynthase domain (FASx sample)
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PSK
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BU of 8psk by Molmil
Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosynthase domain (FASx sample)
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PSJ
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BU of 8psj by Molmil
Asymmetric unit of the yeast fatty acid synthase in the semi rotated state with ACP at the acetyl transferase domain (FASx sample)
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PSG
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BU of 8psg by Molmil
Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the acetyl transferase domain (FASx sample)
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PSF
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BU of 8psf by Molmil
Asymmetric unit of the yeast fatty acid synthase in non-rotated state with ACP at the acetyl transferase domain (FASx sample)
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PSA
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BU of 8psa by Molmil
Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the ketosynthase domain (FASam sample)
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PS9
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BU of 8ps9 by Molmil
Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosynthase domain (FASam sample)
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PS8
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BU of 8ps8 by Molmil
Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the enoyl reductase domain (FASam sample)
Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-26
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PS2
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BU of 8ps2 by Molmil
Asymmetric unit of the yeast fatty acid synthase with ACP at the enoyl reductase domain (FASam sample)
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PS1
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BU of 8ps1 by Molmil
Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosynthase domain (FASamn sample)
Descriptor: COENZYME A, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PRW
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BU of 8prw by Molmil
Cryo-EM structure of the yeast fatty acid synthase at 1.9 angstrom resolution
Descriptor: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, COENZYME A, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-12
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PRV
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BU of 8prv by Molmil
Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosreductase domain (FASamn sample)
Descriptor: COENZYME A, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
Deposit date:2023-07-12
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8GKF
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BU of 8gkf by Molmil
Phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis in complex with Raltitrexed.
Descriptor: 4'-phosphopantetheinyl transferase PptT, TOMUDEX
Authors:Krieger, I.V, Singh, A, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2023-03-18
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.
Sci Adv, 10, 2024
7W58
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BU of 7w58 by Molmil
Crystal structure of acyl-carrier protein synthase from Mycobacterium smegmatis
Descriptor: 1,2-ETHANEDIOL, 4'-phosphopantetheinyl transferase, NICKEL (II) ION
Authors:Yadav, S, Bhatia, I, Biswal, B.K.
Deposit date:2021-11-29
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Identification, structure determination and analysis of Mycobacterium smegmatis acyl-carrier protein synthase (AcpS) crystallized serendipitously.
Acta Crystallogr.,Sect.F, 78, 2022
7TUI
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BU of 7tui by Molmil
Structure of C. albicans FAS in an inhibited state
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Lou, J.W, Mazhab-Jafari, M.T.
Deposit date:2022-02-02
Release date:2023-02-15
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structure of C. albicans FAS in an inhibited state.
To Be Published
7R49
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BU of 7r49 by Molmil
Crystal structure of the L. plantarum acyl carrier protein synthase (AcpS)in complex with D-alanyl carrier protein (DltC1)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4'-PHOSPHOPANTETHEINE, D-alanyl carrier protein 1, ...
Authors:Nikolopoulos, N, Ravaud, S, Simorre, J.P, Grangeasse, C.
Deposit date:2022-02-08
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid D-alanylation pathway of Lactiplantibacillus plantarum.
Sci Rep, 12, 2022
7Q5S
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BU of 7q5s by Molmil
Protein community member fatty acid synthase complex from C. thermophilum
Descriptor: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 3-oxoacyl-[acyl-carrier-protein] reductase
Authors:Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L.
Deposit date:2021-11-04
Release date:2022-02-02
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (4.47 Å)
Cite:Cryo-EM and artificial intelligence visualize endogenous protein community members.
Structure, 30, 2022
7N8M
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BU of 7n8m by Molmil
PptT PAP(CoA) 8978B complex
Descriptor: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2021-06-15
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
7N8L
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BU of 7n8l by Molmil
PptT PAP(CoA) 9016 complex
Descriptor: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2021-06-15
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
7N8E
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BU of 7n8e by Molmil
PptT PAP(CoA) 9056 complex
Descriptor: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2021-06-14
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
7ED2
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BU of 7ed2 by Molmil
Transferase from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase, ADENOSINE-3'-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Kim, D.-G, Lee, B.-J, Lee, S.J.
Deposit date:2021-03-15
Release date:2022-03-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Transferase from Mycobacterium tuberculosis
To Be Published
7ED1
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BU of 7ed1 by Molmil
Transferase from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase, CALCIUM ION, COENZYME A, ...
Authors:Kim, D.-G, Lee, B.-J, Lee, S.J.
Deposit date:2021-03-15
Release date:2022-03-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Transferase from Mycobacterium tuberculosis
To Be Published
7ED0
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BU of 7ed0 by Molmil
Transferase from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase superfamily protein, COENZYME A, SULFATE ION
Authors:Kim, D.-G, Lee, B.-J, Lee, S.J.
Deposit date:2021-03-15
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Transferase from Mycobacterium tuberculosis
To Be Published

 

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