8J2G
| Human ZnT1-D47N/D255N mutant | Descriptor: | Proton-coupled zinc antiporter SLC30A1 | Authors: | Sun, L, Liu, X, Sun, C, He, B. | Deposit date: | 2023-04-14 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the human ZnT1-D47N/D255N double mutant To Be Published
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8ZSZ
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8ZSB
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7Y5G
| Cryo-EM structure of a eukaryotic ZnT8 in the presence of zinc | Descriptor: | ZINC ION, Zinc transporter 8 | Authors: | Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X. | Deposit date: | 2022-06-17 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism. J.Struct.Biol., 215, 2022
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7Y5H
| Cryo-EM structure of a eukaryotic ZnT8 at a low pH | Descriptor: | ZINC ION, Zinc transporter 8 | Authors: | Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X. | Deposit date: | 2022-06-17 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism. J.Struct.Biol., 215, 2022
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6XPE
| Cryo-EM structure of human ZnT8 WT, in the presence of zinc, determined in outward-facing conformation | Descriptor: | ZINC ION, Zinc transporter 8 | Authors: | Bai, X.C, Xue, J, Jiang, Y.X. | Deposit date: | 2020-07-08 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations. Elife, 9, 2020
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6XPF
| Cryo-EM structure of human ZnT8 WT, in the absence of zinc, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation | Descriptor: | ZINC ION, Zinc transporter 8 | Authors: | Bai, X.C, Xue, J, Jiang, Y.X. | Deposit date: | 2020-07-08 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations. Elife, 9, 2020
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6XPD
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8J7W
| Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-bound conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7X
| Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7V
| Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J80
| Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-unbound conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7U
| Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7T
| Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7Y
| Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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2QFI
| Structure of the zinc transporter YiiP | Descriptor: | Ferrous-iron efflux pump fieF, ZINC ION | Authors: | Lu, M. | Deposit date: | 2007-06-27 | Release date: | 2007-10-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of the zinc transporter YiiP. Science, 317, 2007
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5VRF
| CryoEM Structure of the Zinc Transporter YiiP from helical crystals | Descriptor: | Cadmium and zinc efflux pump FieF, ZINC ION | Authors: | Coudray, N, Lopez-Redondo, M, Zhang, Z, Alexopoulos, J, Stokes, D.L, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) | Deposit date: | 2017-05-10 | Release date: | 2018-03-14 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis for the alternating access mechanism of the cation diffusion facilitator YiiP. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7KZX
| Cryo-EM structure of YiiP-Fab complex in Apo state | Descriptor: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain | Authors: | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | Deposit date: | 2020-12-10 | Release date: | 2021-01-06 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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7KZZ
| Cryo-EM structure of YiiP-Fab complex in Holo state | Descriptor: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain, ... | Authors: | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | Deposit date: | 2020-12-10 | Release date: | 2021-01-06 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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3H90
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3J1Z
| Inward-Facing Conformation of the Zinc Transporter YiiP revealed by Cryo-electron Microscopy | Descriptor: | Cation efflux family protein | Authors: | Coudray, N, Valvo, S, Hu, M, Lasala, R, Kim, C, Vink, M, Zhou, M, Provasi, D, Filizola, M, Tao, J, Fang, J, Penczek, P.A, Ubarretxena-Belandia, I, Stokes, D.L, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) | Deposit date: | 2012-07-24 | Release date: | 2012-10-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy. Proc.Natl.Acad.Sci.USA, 110, 2013
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8F6H
| Cryo-EM structure of a Zinc-loaded asymmetrical TMD D70A mutant of the YiiP-Fab complex | Descriptor: | Cadmium and zinc efflux pump FieF, Fab2r heavy chain, Fab2r light chain, ... | Authors: | Lopez-Redondo, M.L, Hussein, A.K, Stokes, D.L. | Deposit date: | 2022-11-16 | Release date: | 2023-02-08 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Energy coupling and stoichiometry of Zn 2+ /H + antiport by the prokaryotic cation diffusion facilitator YiiP. Elife, 12, 2023
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8F6E
| Cryo-EM structure of a Zinc-loaded wild-type YiiP-Fab complex | Descriptor: | Cadmium and zinc efflux pump FieF, Fab heavy chain, Fab light chain, ... | Authors: | Lopez-Redondo, M.L, Hussein, A.K, Stokes, D.L. | Deposit date: | 2022-11-16 | Release date: | 2023-02-08 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Energy coupling and stoichiometry of Zn 2+ /H + antiport by the prokaryotic cation diffusion facilitator YiiP. Elife, 12, 2023
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8F6K
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8F6F
| Cryo-EM structure of a Zinc-loaded D51A mutant of the YiiP-Fab complex | Descriptor: | Cadmium and zinc efflux pump FieF, Fab2r heavy chain, Fab2r light chain, ... | Authors: | Lopez-Redondo, M.L, Hussein, A.K, Stokes, D.L. | Deposit date: | 2022-11-16 | Release date: | 2023-02-08 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Energy coupling and stoichiometry of Zn 2+ /H + antiport by the prokaryotic cation diffusion facilitator YiiP. Elife, 12, 2023
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