1NXM
  • Download 1nxm
  • View 1nxm
Molmil generated image of 1nxm
THE HIGH RESOLUTION STRUCTURES OF RMLC FROM STREPTOCOCCUS SUIS
Descriptor:dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
Authors:Dong, C., Major, L.L., Allen, A., Blankenfeldt, W., Maskell, D., Naismith, J.H.
Deposit date:2003-02-11
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-Resolution Structures of RmlC from Streptococcus suis in Complex with Substrate Analogs Locate the Active Site of This Class of Enzyme
Structure, 11, 2003
1OFN
  • Download 1ofn
  • View 1ofn
Molmil generated image of 1ofn
PURIFICATION, CRYSTALLISATION AND PRELIMINARY STRUCTURAL STUDIES OF DTDP-4-KETO-6-DEOXY-GLUCOSE-5-EPIMERASE (EVAD) FROM AMYCOLATOPSIS ORIENTALIS; THE FOURTH ENZYME IN THE DTDP-L-EPIVANCOSAMINE BIOSYNTHETIC PATHWAY.
Descriptor:PCZA361.16, GLYCEROL
Authors:Merkel, A.B., Naismith, J.H.
Deposit date:2003-04-17
Release date:2004-04-15
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Purification, Crystallization and Preliminary Structural Studies of Dtdp-4-Keto-6-Deoxy-Glucose-5-Epimerase (Evad) from Amycolatopsis Orientalis, the Fourth Enzyme in the Dtdp-L-Epivancosamine Biosynthetic Pathway.
Acta Crystallogr.,Sect.D, 58, 2002
1PM7
  • Download 1pm7
  • View 1pm7
Molmil generated image of 1pm7
RMLC (DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE)STRUCTURE FROM MYCOBACTERIUM TUBERCULOSIS AND INHIBITOR DESIGN. THE APO STRUCTURE.
Descriptor:RFBC, ACETATE ION, GLYCEROL
Authors:Dong, C., Naismith, J.H., TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-06-10
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis.
Bioorg.Med.Chem.Lett., 13, 2003
1RTV
  • Download 1rtv
  • View 1rtv
Molmil generated image of 1rtv
RMLC (DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE) CRYSTAL STRUCTURE FROM PSEUDOMONAS AERUGINOSA, APO STRUCTURE
Descriptor:dTDP-4-dehydrorhamnose 3,5-epimerase, S,R MESO-TARTARIC ACID
Authors:Dong, C.J., Naismith, J.H.
Deposit date:2003-12-10
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:RmlC (dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase) crystal structure from Pseudomonas aeruginosa, apo structure
TO BE PUBLISHED
1UPI
  • Download 1upi
  • View 1upi
Molmil generated image of 1upi
MYCOBACTERIUM TUBERCULOSIS RMLC EPIMERASE (RV3465)
Descriptor:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE
Authors:Kim, C.-Y., Naranjo, C., Waldo, G.S., Lekin, T., Segelke, B.W., Kantardjieff, K.A., Zemla, A., Terwilliger, T., Rupp, B., TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-10-05
Release date:2003-10-07
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mycobacterium Tuberculosis Rmlc Epimerase (Rv3465): A Promising Drug-Target Structure in the Rhamnose Pathway
Acta Crystallogr.,Sect.D, 60, 2004
1WA4
  • Download 1wa4
  • View 1wa4
Molmil generated image of 1wa4
CRYSTAL STRUCTURE OF THE M131F L135A EVAD DOUBLE MUTANT
Descriptor:PCZA361.16, GLYCEROL
Authors:Merkel, A.B., Naismith, J.H.
Deposit date:2004-10-22
Release date:2007-01-30
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the M131F L135A Evad Double Mutant
To be Published
1WLT
  • Download 1wlt
  • View 1wlt
Molmil generated image of 1wlt
CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE HOMOLOGUE FROM SULFOLOBUS TOKODAII
Descriptor:176aa long hypothetical dTDP-4-dehydrorhamnose 3,5-epimerase
Authors:Watanabe, N., Sakai, N., Zilian, Z., Kawarabayasi, Y., Tanaka, I.
Deposit date:2004-06-29
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of dTDP-4-dehydrorhamnose 3,5-epimerase homologue
to be published
2C0Z
  • Download 2c0z
  • View 2c0z
Molmil generated image of 2c0z
THE 1.6 A RESOLUTION CRYSTAL STRUCTURE OF NOVW: A 4-KETO-6-DEOXY SUGAR EPIMERASE FROM THE NOVOBIOCIN BIOSYNTHETIC GENE CLUSTER OF STREPTOMYCES SPHEROIDES
Descriptor:NOVW, SULFATE ION, 1,2-ETHANEDIOL
Authors:Jakimowicz, P., Tello, M., Freel-Meyers, C.L., Walsh, C.T., Buttner, M.J., Field, R.A., Lawson, D.M.
Deposit date:2005-09-09
Release date:2006-01-25
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The 1.6 A Resolution Crystal Structure of Novw: A 4-Keto-6-Deoxy Sugar Epimerase from the Novobiocin Biosynthetic Gene Cluster of Streptomyces Spheroides
Proteins, 63, 2006
2IXC
  • Download 2ixc
  • View 2ixc
Molmil generated image of 2ixc
RMLC M. TUBERCULOSIS WITH DTDP-RHAMNOSE
Descriptor:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC, 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE
Authors:Dong, C., Naismith, J.H.
Deposit date:2006-07-07
Release date:2006-10-26
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXH
  • Download 2ixh
  • View 2ixh
Molmil generated image of 2ixh
RMLC P AERUGINOSA WITH DTDP-RHAMNOSE
Descriptor:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE
Authors:Dong, C., Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-10-26
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation.
J. Mol. Biol., 365, 2007
2IXI
  • Download 2ixi
  • View 2ixi
Molmil generated image of 2ixi
RMLC P AERUGINOSA WITH DTDP-XYLOSE
Descriptor:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, THYMIDINE-5'-DIPHOSPHATE, S,R MESO-TARTARIC ACID
Authors:Dong, C., Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXJ
  • Download 2ixj
  • View 2ixj
Molmil generated image of 2ixj
RMLC P AERUGINOSA NATIVE
Descriptor:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, S,R MESO-TARTARIC ACID
Authors:Dong, C., Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXK
  • Download 2ixk
  • View 2ixk
Molmil generated image of 2ixk
RMLC P AERUGINOSA WITH DTDP-4-KETO RHAMNNOSE (THE PRODUCT OF THE REACTION)
Descriptor:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, DTDP-4-KETO-L-RHAMNOSE
Authors:Dong, C., Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXL
  • Download 2ixl
  • View 2ixl
Molmil generated image of 2ixl
RMLC S. SUIS WITH DTDP-RHAMNOSE
Descriptor:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, NICKEL (II) ION
Authors:Dong, C., Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
3RYK
  • Download 3ryk
  • View 3ryk
Molmil generated image of 3ryk
1.63 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (RFBC) FROM BACILLUS ANTHRACIS STR. AMES WITH TDP AND PPI BOUND
Descriptor:dTDP-4-dehydrorhamnose 3,5-epimerase, PYROPHOSPHATE 2-, THYMIDINE-5'-DIPHOSPHATE
Authors:Halavaty, A.S., Kuhn, M., Minasov, G., Shuvalova, L., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-05-11
Release date:2011-05-25
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.631 Å)
Cite:Structure of the Bacillus anthracis dTDP-L-rhamnose-biosynthetic enzyme dTDP-4-dehydrorhamnose 3,5-epimerase (RfbC).
Acta Crystallogr F Struct Biol Commun, 73, 2017
5BUV
  • Download 5buv
  • View 5buv
Molmil generated image of 5buv
X-RAY STRUCTURE OF WBCA FROM YERSINIA ENTEROCOLITICA
Descriptor:Putative epimerase, PHOSPHATE ION, 6-AMINOPYRIMIDIN-2(1H)-ONE, ...
Authors:Holden, H.M., Salinger, A.J., Brown, H.A., Thoden, J.B.
Deposit date:2015-06-04
Release date:2015-08-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Biochemical studies on WbcA, a sugar epimerase from Yersinia enterocolitica.
Protein Sci., 24, 2015
6C46
  • Download 6c46
  • View 6c46
Molmil generated image of 6c46
CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM ELIZABETHKINGIA ANOPHELIS NUHP1
Descriptor:dTDP-4-dehydrorhamnose 3,5-epimerase, CALCIUM ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-11
Release date:2018-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of dTDP-4-dehydrorhamnose 3,5-epimerase from Elizabethkingia anophelis NUHP1
To be Published
6DIN
  • Download 6din
  • View 6din
Molmil generated image of 6din
HIGH RESOLUTIONSTRUCTURE OF APO DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE
Descriptor:dTDP-4-dehydrorhamnose 3,5-epimerase, SULFATE ION
Authors:Chang, C., Jedrzejczak, R., Chhor, G., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-05-23
Release date:2018-05-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High resolutionstructure of apo dTDP-4-dehydrorhamnose 3,5-epimerase
To Be Published
7AN4
  • Download 7an4
  • View 7an4
Molmil generated image of 7an4
MLGHB, GDP-MANNOHEPTOSE C3,5 EPIMERASE FROM CAMPYLOBACTER JEJUNI COMPLEX WITH GDP-MANNOSE
Descriptor:Thymidine diphospho-4-keto-rhamnose 3,5-epimerase, GUANOSINE-5'-DIPHOSPHATE
Authors:Naismith, J.H., Woodward, L.
Deposit date:2020-10-10
Release date:2020-10-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:MghlB with GDP
To Be Published
171313
PDB entries from 2020-11-18