8QLD
| Bacteriophage T5 dUTPase mutant with loop deletion (30-35 aa) | Descriptor: | CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL, ... | Authors: | Gabdulkhakov, A.G, Dzhus, U.F, Selikhanov, G.K, Glukhov, A.S. | Deposit date: | 2023-09-19 | Release date: | 2024-01-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Bacteriophage T5 dUTPase: Combination of Common Enzymatic and Novel Functions. Int J Mol Sci, 25, 2024
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8QKY
| Bacteriophage T5 dUTPase | Descriptor: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL | Authors: | Gabdulkhakov, A.G, Dzhus, U.F, Selikhanov, G.K, Glukhov, A.S. | Deposit date: | 2023-09-18 | Release date: | 2024-01-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Bacteriophage T5 dUTPase: Combination of Common Enzymatic and Novel Functions. Int J Mol Sci, 25, 2024
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8K6W
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8HRV
| dutpase of helicobacter pylori 26695 | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Kumari, K, Gourinath, S. | Deposit date: | 2022-12-16 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | dutpase of helicobacter pylori 26695 To Be Published
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8CGA
| Structure of Mycobacterium tuberculosis dUTPase delta 133A-137S mutant | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Toth, Z.S, Benedek, A, Leveles, I, Vertessy, B.G. | Deposit date: | 2023-02-03 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of Mycobacterium tuberculosis dUTPase delta 133A-137S mutant To Be Published
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8C8I
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7PWX
| dUTPase from M. tuberculosis in complex with Stl | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Marina, A, Sanz-Frasquet, C. | Deposit date: | 2021-10-07 | Release date: | 2022-12-28 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Bacteriophage-Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases. Microbiol Spectr, 11, 2023
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7PWJ
| dUTPase from human in complex with Stl | Descriptor: | 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, ... | Authors: | Sanz-Frasquet, C, Marina, A. | Deposit date: | 2021-10-06 | Release date: | 2022-12-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.944 Å) | Cite: | The Bacteriophage-Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases. Microbiol Spectr, 11, 2023
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7N6S
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7N56
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7DLV
| shrimp dUTPase in complex with Stl | Descriptor: | CALCIUM ION, Orf20, SULFATE ION, ... | Authors: | Ma, Q, Wang, F. | Deposit date: | 2020-11-30 | Release date: | 2021-12-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.525 Å) | Cite: | Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase. Int.J.Biol.Macromol., 184, 2021
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7BPD
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6MJK
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6MAO
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6MAI
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6LJO
| African swine fever virus dUTPase | Descriptor: | E165R | Authors: | Liang, R, Peng, G.Q. | Deposit date: | 2019-12-17 | Release date: | 2020-11-11 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development. J.Biol.Chem., 296, 2020
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6LJJ
| Swine dUTPase in complex with alpha,beta-iminodUTP and magnesium ion | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 1, ... | Authors: | Liang, R, Peng, G.Q. | Deposit date: | 2019-12-16 | Release date: | 2020-11-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development. J.Biol.Chem., 296, 2020
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6LJ3
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6LIS
| ASFV dUTPase in complex with dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R | Authors: | Liang, R, Peng, G.Q. | Deposit date: | 2019-12-12 | Release date: | 2020-11-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development. J.Biol.Chem., 296, 2020
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6KZ6
| Crystal structure of ASFV dUTPase | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R, MAGNESIUM ION | Authors: | Guo, Y, Chen, C, Li, G.B, Cao, L, Wang, C.W. | Deposit date: | 2019-09-23 | Release date: | 2019-11-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.187 Å) | Cite: | Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family. J.Virol., 94, 2020
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6KY9
| Crystal structure of ASFV dUTPase and UMP complex | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
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6KY8
| Crystal structure of ASFV dUTPase | Descriptor: | E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
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6HDE
| Structure of Escherichia coli dUTPase Q93H mutant | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION | Authors: | Benedek, A, Vertessy, B.G, Leveles, I. | Deposit date: | 2018-08-17 | Release date: | 2019-08-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | The Role of a Key Amino Acid Position in Species-Specific Proteinaceous dUTPase Inhibition. Biomolecules, 9, 2019
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6H4C
| A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature. | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, NICKEL (II) ION, ... | Authors: | Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A. | Deposit date: | 2018-07-20 | Release date: | 2019-08-28 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature. Nat Commun, 10, 2019
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5Y5Q
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