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7W0Q
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BU of 7w0q by Molmil
TRIM7 in complex with C-terminal peptide of 2C
Descriptor: E3 ubiquitin-protein ligase TRIM7, peptide
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2021-11-18
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
6ITA
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BU of 6ita by Molmil
Crystal structure of intracellular B30.2 domain of BTN3A1 mutant
Descriptor: Butyrophilin subfamily 3 member A1
Authors:Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H.
Deposit date:2018-11-20
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
5C33
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BU of 5c33 by Molmil
Crystal Structure of Mouse Ryanodine Receptor 2 SPRY1 Domain
Descriptor: CHLORIDE ION, ISOPROPYL ALCOHOL, Ryanodine receptor 2
Authors:Yuchi, Z, Van Petegem, F.
Deposit date:2015-06-16
Release date:2015-08-05
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.
Nat Commun, 6, 2015
6JWM
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BU of 6jwm by Molmil
Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction
Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2
Authors:Li, K, Kuang, Z.
Deposit date:2019-04-21
Release date:2020-04-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Crystal structure of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction
To Be Published
6KEY
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BU of 6key by Molmil
Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2)
Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2
Authors:Li, K, Kuang, Z.
Deposit date:2019-07-05
Release date:2020-07-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase.
Nitric Oxide, 113-114, 2021
7X70
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BU of 7x70 by Molmil
TRIM7 in complex with C-terminal peptide of NSP8
Descriptor: E3 ubiquitin-protein ligase TRIM7, peptide
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2022-03-08
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
6ISM
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BU of 6ism by Molmil
Crystal structure of intracellular B30.2 domain of BTN3A1 mutant
Descriptor: Butyrophilin subfamily 3 member A1
Authors:Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H.
Deposit date:2018-11-16
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
2VOK
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BU of 2vok by Molmil
Murine TRIM21
Descriptor: 52 KDA RO PROTEIN
Authors:Keeble, A.H, Khan, Z, Forster, A, James, L.C.
Deposit date:2008-02-19
Release date:2008-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved.
Proc.Natl.Acad.Sci.USA, 105, 2008
8PD6
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BU of 8pd6 by Molmil
Crystal structure of the TRIM58 PRY-SPRY domain in complex with TRIM-473
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase TRIM58, ...
Authors:Renatus, M, Hoegenauer, K, Schroeder, M.
Deposit date:2023-06-11
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
Acs Med.Chem.Lett., 14, 2023
5XN3
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BU of 5xn3 by Molmil
Crystal structure of SPSB2 in complex with a rational designed RGD containing cyclic peptide inhibitor of SPSB2-iNOS interaction
Descriptor: SPRY domain-containing SOCS box protein 2, cR8 peptide from NOS2
Authors:You, T, Kuang, Z.
Deposit date:2017-05-17
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Crystal structure of SPSB2 in complex with a rational designed RGD-containing cyclic peptide inhibitor of SPSB2-iNOS interaction.
Biochem. Biophys. Res. Commun., 489, 2017
4P9I
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BU of 4p9i by Molmil
Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253)
Descriptor: Ryanodine receptor 2
Authors:Lau, K, Van Petegem, F.
Deposit date:2014-04-04
Release date:2014-11-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.3401 Å)
Cite:Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
2WL1
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BU of 2wl1 by Molmil
Pyrin PrySpry domain
Descriptor: 1,2-ETHANEDIOL, PYRIN, THIOCYANATE ION
Authors:Weinert, C, Mittl, P.R, Gruetter, M.G.
Deposit date:2009-06-19
Release date:2009-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever.
J.Mol.Biol., 394, 2009
7X6Y
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BU of 7x6y by Molmil
TRIM7 in complex with C-terminal peptide of NSP5
Descriptor: E3 ubiquitin-protein ligase TRIM7, peptide
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2022-03-08
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
6DN7
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BU of 6dn7 by Molmil
SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor
Descriptor: CHLORIDE ION, SPRY domain-containing SOCS box protein 4, WDINNN(BAL) Cyclic peptide inhibitor
Authors:Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
Deposit date:2018-06-06
Release date:2019-04-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
8IZE
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BU of 8ize by Molmil
Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 4-HMBPP
Descriptor: Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, [(E)-3-(hydroxymethyl)pent-2-enyl] phosphono hydrogen phosphate
Authors:Yang, Y.Y, Yi, S.M, Huang, J.W, Chen, C.C, Guo, R.T.
Deposit date:2023-04-07
Release date:2023-09-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
7W0S
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BU of 7w0s by Molmil
TRIM7 in complex with C-terminal peptide of 2C
Descriptor: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase TRIM7, GLYCEROL, ...
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2021-11-18
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
4N7I
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BU of 4n7i by Molmil
Crystal Structure of Intracellular B30.2 Domain of BTN3A1
Descriptor: BETA-MERCAPTOETHANOL, Butyrophilin subfamily 3 member A1, CHLORIDE ION, ...
Authors:Sandstrom, A, Adams, E.J.
Deposit date:2013-10-15
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4015 Å)
Cite:The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human V gamma 9V delta 2 T Cells.
Immunity, 40, 2014
7X6Z
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BU of 7x6z by Molmil
TRIM7 in complex with C-terminal peptide of NSP12
Descriptor: E3 ubiquitin-protein ligase TRIM7, peptide
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2022-03-08
Release date:2022-08-10
Last modified:2022-11-09
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
4P9L
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BU of 4p9l by Molmil
Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253) disease mutant A1107M
Descriptor: Ryanodine receptor 2
Authors:Lau, K, Van Petegem, F.
Deposit date:2014-04-04
Release date:2014-11-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4361 Å)
Cite:Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
5VSN
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BU of 5vsn by Molmil
Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L
Descriptor: GLYCEROL, POTASSIUM ION, Ryanodine receptor 2
Authors:Yuchi, Z, Van Petegem, F.
Deposit date:2017-05-12
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.439 Å)
Cite:Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2.
JCI Insight, 5, 2019
6J6L
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BU of 6j6l by Molmil
Crystal structure of mouse Ryanodine Receptor 2 SPRY1 Domain (650-844) disease mutant I784F
Descriptor: ISOPROPYL ALCOHOL, Ryanodine receptor 2
Authors:Ma, R, Lin, L, Yuchi, Z.
Deposit date:2019-01-15
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:A SPRY1 domain cardiac ryanodine receptor variant associated with short-coupled torsade de pointes.
Sci Rep, 11, 2021
4N7U
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BU of 4n7u by Molmil
Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP
Descriptor: Butyrophilin subfamily 3 member A1, GLYCEROL, [(E)-4-methyl-5-oxidanyl-pent-3-enyl]-phosphonooxy-phosphinic acid
Authors:Sandstrom, A, Adams, E.J.
Deposit date:2013-10-16
Release date:2014-04-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4598 Å)
Cite:The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human V gamma 9V delta 2 T Cells.
Immunity, 40, 2014
7B2S
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BU of 7b2s by Molmil
Crystal structure of SPRY domain of TRIM9
Descriptor: E3 ubiquitin-protein ligase TRIM9, SULFATE ION
Authors:Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2020-11-27
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of SPRY domain of TRIM9
To Be Published
8JYA
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BU of 8jya by Molmil
Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with IPP
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Butyrophylin 3, SULFATE ION
Authors:Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T.
Deposit date:2023-07-03
Release date:2023-09-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
6SJH
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BU of 6sjh by Molmil
Structure of the PRY-SPRY domain of human Trim16L/Trim70
Descriptor: Tripartite motif-containing protein 16-like protein
Authors:Mikkelsen, J.H, Andersen, C.B.F.
Deposit date:2019-08-13
Release date:2021-02-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the PRY-SPRY domain of human Trim16L/Trim70
To Be Published

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