1CDZ
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BRCT DOMAIN FROM DNA-REPAIR PROTEIN XRCC1
Descriptor:PROTEIN (DNA-REPAIR PROTEIN XRCC1)
Authors:Zhang, X., Morera, S., Bates, P., Whitehead, P., Coffer, A., Hainbucher, K., Nash, R., Sternberg, M., Lindahl, T., Freemont, P.
Deposit date:1999-03-04
Release date:2000-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.
EMBO J., 17, 1998
1JNX
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CRYSTAL STRUCTURE OF THE BRCT REPEAT REGION FROM THE BREAST CANCER ASSOCIATED PROTEIN, BRCA1
Descriptor:BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, NICKEL (II) ION
Authors:Williams, R.S., Green, R., Glover, J.N.M.
Deposit date:2001-07-26
Release date:2001-09-21
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1.
Nat.Struct.Biol., 8, 2001
1L0B
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CRYSTAL STRUCTURE OF RAT BRCA1 TANDEM-BRCT REGION
Descriptor:BRCA1
Authors:Joo, W.S., Jeffrey, P.D., Cantor, S.B., Finnin, M.S., Livingston, D.M., Pavletich, N.P.
Deposit date:2002-02-08
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
Genes Dev., 16, 2002
1L7B
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SOLUTION NMR STRUCTURE OF BRCT DOMAIN OF T. THERMOPHILUS: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET WR64TT
Descriptor:DNA LIGASE
Authors:Sahota, G., Dixon, B.L., Huang, Y.P., Aramini, J., Monleon, D., Bhattacharya, D., Swapna, G.V.T., Yin, C., Xiao, R., Anderson, S., Tejero, R., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-03-14
Release date:2003-09-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of the Brct Domain from Thermus Thermophilus DNA Ligase
To be Published
1N5O
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STRUCTURAL CONSEQUENCES OF A CANCER-CAUSING BRCA1-BRCT MISSENSE MUTATION
Descriptor:Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S., Glover, J.N.M.
Deposit date:2002-11-06
Release date:2002-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
J.Biol.Chem., 278, 2003
1OQA
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SOLUTION STRUCTURE OF THE BRCT-C DOMAIN FROM HUMAN BRCA1
Descriptor:Breast cancer type 1 susceptibility protein
Authors:Gaiser, O.J., Ball, L.J., Schmieder, P., Leitner, D., Strauss, H., Wahl, M., Kuhne, R., Oschkinat, H., Heinemann, U.
Deposit date:2003-03-07
Release date:2004-06-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.
Biochemistry, 43, 2004
1T15
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CRYSTAL STRUCTURE OF THE BRCA1 BRCT DOMAINS IN COMPLEX WITH THE PHOSPHORYLATED INTERACTING REGION FROM BACH1 HELICASE
Descriptor:Breast cancer type 1 susceptibility protein, BRCA1 interacting protein C-terminal helicase 1
Authors:Clapperton, J.A., Manke, I.A., Lowery, D.M., Ho, T., Haire, L.F., Yaffe, M.B., Smerdon, S.J.
Deposit date:2004-04-15
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
Nat.Struct.Mol.Biol., 11, 2004
1T29
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CRYSTAL STRUCTURE OF THE BRCA1 BRCT REPEATS BOUND TO A PHOSPHORYLATED BACH1 PEPTIDE
Descriptor:Breast cancer type 1 susceptibility protein, BACH1 phosphorylated peptide
Authors:Shiozaki, E.N., Gu, L., Yan, N., Shi, Y.
Deposit date:2004-04-20
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling.
Mol.Cell, 14, 2004
1T2U
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STRUCTURAL BASIS OF PHOSPHOPEPTIDE RECOGNITION BY THE BRCT DOMAIN OF BRCA1: STRUCTURE OF BRCA1 MISSENSE VARIANT V1809F
Descriptor:Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S., Lee, M.S., Duong, D.D., Glover, J.N.M.
Deposit date:2004-04-22
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1T2V
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STRUCTURAL BASIS OF PHOSPHO-PEPTIDE RECOGNITION BY THE BRCT DOMAIN OF BRCA1, STRUCTURE WITH PHOSPHOPEPTIDE
Descriptor:Breast cancer type 1 susceptibility protein, BRCTide-7PS
Authors:Williams, R.S., Lee, M.S., Hau, D.D., Glover, J.N.M.
Deposit date:2004-04-22
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1WF6
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THE THIRD BRCA1 C-TERMINUS (BRCT) DOMAIN OF SIMILAR TO S.POMBE RAD4+/CUT5+ PRODUCT
Descriptor:Similar to S.pombe -rad4+/cut5+product (A40727)
Authors:Nagashima, T., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-26
Release date:2004-11-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
TO BE PUBLISHED
1Y98
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STRUCTURE OF THE BRCT REPEATS OF BRCA1 BOUND TO A CTIP PHOSPHOPEPTIDE.
Descriptor:Breast cancer type 1 susceptibility protein, CtIP PHOSPHORYLATED PEPTIDE, COBALT (II) ION, ...
Authors:Varma, A.K., Brown, R.S., Birrane, G., Ladias, J.A.A.
Deposit date:2004-12-14
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005
1Z56
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CO-CRYSTAL STRUCTURE OF LIF1P-LIG4P
Descriptor:Ligase interacting factor 1, DNA ligase IV
Authors:Dore, A.S., Furnham, N., Davies, O.R., Sibanda, B.L., Chirgadze, D.Y., Jackson, S.P., Pellegrini, L., Blundell, T.L.
Deposit date:2005-03-17
Release date:2006-01-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode.
DNA REPAIR, 5, 2006
2COE
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SOLUTION STRUCTURE OF BRCT DOMAIN OF TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE
Descriptor:deoxynucleotidyltransferase, terminal variant
Authors:Nagashima, T., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-17
Release date:2005-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of BRCT domain of terminal deoxynucleotidyltransferase
To be Published
2COU
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SOLUTION STRUCTURE OF THE SECOND BRCT DOMAIN OF EPITHELIAL CELL TRANSFORMING 2
Descriptor:ECT2 protein
Authors:Nagashima, T., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-18
Release date:2005-11-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the second BRCT domain of epithelial cell transforming 2
To be published
2D8M
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SOLUTION STRUCTURE OF THE FIRST BRCT DOMAIN OF DNA-REPAIR PROTEIN XRCC1
Descriptor:DNA-repair protein XRCC1
Authors:Nagashima, T., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-06
Release date:2006-06-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the first BRCT domain of DNA-repair protein XRCC1
To be published
2E2W
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SOLUTION STRUCTURE OF THE FIRST BRCT DOMAIN OF HUMAN DNA LIGASE IV
Descriptor:DNA ligase 4
Authors:Nagashima, T., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-11-17
Release date:2006-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the first BRCT domain of human DNA ligase IV
TO BE PUBLISHED
2EBU
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SOLUTION STRUCTURE OF THE BRCT DOMAIN FROM HUMAN REPLICATION FACTOR C LARGE SUBUNIT 1
Descriptor:Replication factor C subunit 1
Authors:Nagashima, T., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-09
Release date:2007-08-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the BRCT domain from human replication factor C large subunit 1
To be Published
2ING
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X-RAY STRUCTURE OF THE BRCA1 BRCT MUTANT M1775K
Descriptor:Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Birrane, G., Soni, A., Ladias, J.A.A.
Deposit date:2006-10-07
Release date:2007-09-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
2K6G
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SOLUTION STRUCTURE OF THE DNA BINDING BRCT DOMAIN FROM THE LARGE SUBUNIT OF HUMAN REPLICATION FACTOR C
Descriptor:Replication factor C subunit 1
Authors:Kobayashi, M., Siegal, G., Ab, E., Bonvin, A.M.J.J.
Deposit date:2008-07-09
Release date:2009-09-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the DNA bound BRCT domain from human Replication Factor C p140
To be Published
2K7F
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HADDOCK CALCULATED MODEL OF THE COMPLEX BETWEEN THE BRCT REGION OF RFC P140 AND DSDNA
Descriptor:Replication factor C subunit 1, 5'-D(P*DCP*DGP*DAP*DCP*DCP*DTP*DCP*DGP*DAP*DGP*DAP*DTP*DCP*DA)-3', 5'-D(P*DCP*DTP*DCP*DGP*DAP*DGP*DGP*DTP*DCP*DG)-3'
Authors:Kobayashi, M., Ab, E., Bonvin, A., Siegal, G.
Deposit date:2008-08-10
Release date:2009-09-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex.
J.Biol.Chem., 285, 2010
2XNH
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STRUCTURE AND FUNCTION OF THE RAD9-BINDING REGION OF THE DNA DAMAGE CHECKPOINT ADAPTOR TOPBP1
Descriptor:DNA TOPOISOMERASE 2-BINDING PROTEIN 1, IODIDE ION
Authors:Rappas, M., Oliver, A.W., Pearl, L.H.
Deposit date:2010-08-02
Release date:2010-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and Function of the Rad9-Binding Region of the DNA-Damage Checkpoint Adaptor Topbp1.
Nucleic Acids Res., 39, 2011
2XNK
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STRUCTURE AND FUNCTION OF THE RAD9-BINDING REGION OF THE DNA DAMAGE CHECKPOINT ADAPTOR TOPBP1
Descriptor:DNA TOPOISOMERASE 2-BINDING PROTEIN 1, GLYCEROL
Authors:Rappas, M., Oliver, A.W., Pearl, L.H.
Deposit date:2010-08-03
Release date:2010-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Function of the Rad9-Binding Region of the DNA-Damage Checkpoint Adaptor Topbp1.
Nucleic Acids Res., 39, 2011
3COJ
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CRYSTAL STRUCTURE OF THE BRCT DOMAINS OF HUMAN BRCA1 IN COMPLEX WITH A PHOSPHORYLATED PEPTIDE FROM HUMAN ACETYL-COA CARBOXYLASE 1
Descriptor:Breast cancer type 1 susceptibility protein, Acetyl-CoA carboxylase 1
Authors:Shen, Y., Tong, L.
Deposit date:2008-03-28
Release date:2008-05-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1
Biochemistry, 47, 2008
3JVE
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CRYSTAL STRUCTURE OF THE SIXTH BRCT DOMAIN OF TOPBP1
Descriptor:DNA topoisomerase 2-binding protein 1
Authors:Leung, C.C., Kellogg, E., Baker, D., Glover, J.N.M.
Deposit date:2009-09-16
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
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