1ARL
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CARBOXYPEPTIDASE A WITH ZN REMOVED
Descriptor:APO-CARBOXYPEPTIDASE A=ALPHA= (COX)
Authors:Greenblatt, H.M., Feinberg, H., Tucker, P.A., Shoham, G.
Deposit date:1994-11-22
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
1ARM
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CARBOXYPEPTIDASE A WITH ZN REPLACED BY HG
Descriptor:HG-CARBOXYPEPTIDASE A=ALPHA= (COX), MERCURY (II) ION, COPPER (II) ION, ...
Authors:Greenblatt, H.M., Feinberg, H., Tucker, P.A., Shoham, G.
Deposit date:1994-11-22
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
1BAV
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CARBOXYPEPTIDASE A COMPLEXED WITH 2-BENZYL-3-IODO-PROPANOIC ACID (BIP)
Descriptor:CARBOXYPEPTIDASE A, ZINC ION, 2-BENZYL-3-IODOPROPANOIC ACID
Authors:Martin, P., Edwards, B.
Deposit date:1996-11-14
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic and computational insight on the mechanism of zinc-ion-dependent inactivation of carboxypeptidase a by 2-benzyl-3-iodopropanoate.
J.Am.Chem.Soc., 118, 1996
1CBX
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND THE BIPRODUCT ANALOG INHIBITOR L-BENZYLSUCCINATE AT 2.0 ANGSTROMS RESOLUTION
Descriptor:CARBOXYPEPTIDASE A, ZINC ION, L-BENZYLSUCCINIC ACID
Authors:Mangani, S., Carloni, P., Orioli, P.
Deposit date:1991-10-31
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the complex between carboxypeptidase A and the biproduct analog inhibitor L-benzylsuccinate at 2.0 A resolution.
J.Mol.Biol., 223, 1992
1CPS
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STRUCTURAL COMPARISON OF SULFODIIMINE AND SULFONAMIDE INHIBITORS IN THEIR COMPLEXES WITH ZINC ENZYMES
Descriptor:CARBOXYPEPTIDASE A, ZINC ION, S-(2-CARBOXY-3-PHENYLPROPYL)THIODIIMINE-S-METHANE
Authors:Cappalonga, A.M., Alexander, R.S., Christianson, D.W.
Deposit date:1992-02-18
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural comparison of sulfodiimine and sulfonamide inhibitors in their complexes with zinc enzymes.
J.Biol.Chem., 267, 1992
1CPX
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BETA FORM OF CARBOXYPEPTIDASE A (RESIDUES 3-307) FROM BOVINE PANCREAS IN AN ORTHORHOMBIC CRYSTAL FORM WITH TWO ZINC IONS IN THE ACTIVE SITE.
Descriptor:PROTEIN (CARBOXYPEPTIDASE A), ZINC ION, HYDROXIDE ION
Authors:Bukrinsky, J.T., Bjerrum, M.J., Kadziola, A.
Deposit date:1998-07-27
Release date:1998-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Native carboxypeptidase A in a new crystal environment reveals a different conformation of the important tyrosine 248.
Biochemistry, 37, 1998
1DTD
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2)
Descriptor:CARBOXYPEPTIDASE A2, METALLOCARBOXYPEPTIDASE INHIBITOR, ZINC ION, ...
Authors:Reverter, D., Fernandez-Catalan, C., Bode, W., Holak, T.A., Aviles, F.X.
Deposit date:2000-01-12
Release date:2000-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7, 2000
1EE3
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CADMIUM-SUBSTITUTED BOVINE PANCREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 7.5 AND 2 MM CHLORIDE IN MONOCLINIC CRYSTAL FORM
Descriptor:PROTEIN (CARBOXYPEPTIDASE A), CADMIUM ION
Authors:Jensen, F., Bukrinsky, T., Bjerrum, J., Larsen, S.
Deposit date:2000-01-30
Release date:2002-06-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function
J.BIOL.INORG.CHEM., 7, 2002
1ELL
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CADMIUM-SUBSTITUTED BOVINE PANCREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 7.5 AND 0.25 M CHLORIDE IN MONOCLINIC CRYSTAL FORM.
Descriptor:CARBOXYPEPTIDASE A, CADMIUM ION
Authors:Jensen, F., Bukrinsky, T., Bjerrum, J., Larsen, S.
Deposit date:2000-03-14
Release date:2002-06-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function
J.BIOL.INORG.CHEM., 7, 2002
1ELM
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CADMIUM-SUBSTITUTED BOVINE PACREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 5.5 AND 2 MM CHLORIDE IN MONOCLINIC CRYSTAL FORM.
Descriptor:CARBOXYPEPTIDASE A, CADMIUM ION
Authors:Jensen, F., Bukrinsky, T., Bjerrum, J., Larsen, S.
Deposit date:2000-03-14
Release date:2002-06-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function
J.BIOL.INORG.CHEM., 7, 2002
1F57
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CARBOXYPEPTIDASE A COMPLEX WITH D-CYSTEINE AT 1.75 A
Descriptor:CARBOXYPEPTIDASE A, ZINC ION, D-CYSTEINE
Authors:van Aalten, D.M., Chong, C.R., Joshua-Tor, L.
Deposit date:2000-06-13
Release date:2000-09-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes.
Biochemistry, 39, 2000
1HDQ
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CRYSTAL STRUCTURE OF BOVINE PANCREATIC CARBOXYPEPTIDASE A COMPLEXED WITH D-N-HYDROXYAMINOCARBONYL PHENYLALANINE AT 2.3 A
Descriptor:CARBOXYPEPTIDASE A, D-[(N-HYDROXYAMINO)CARBONYL]PHENYLALANINE, ZINC ION
Authors:Cho, J.H., Ha, N.-C., Chung, S.J., Kim, D.H., Choi, K.Y., Oh, B.-H.
Deposit date:2000-11-17
Release date:2001-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insight Into the Stereochemistry in the Inhibition of Carboxypeptidase a with N-(Hydroxyaminocarbonyl)Phenylalanine: Binding Modes of an Enantiomeric Pair of the Inhibitor to Carboxypeptidase A
Bioorg.Med.Chem., 10, 2002
1HDU
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CRYSTAL STRUCTURE OF BOVINE PANCREATIC CARBOXYPEPTIDASE A COMPLEXED WITH AMINOCARBONYLPHENYLALANINE AT 1.75 A
Descriptor:CARBOXYPEPTIDASE A, ZINC ION, D-[(AMINO)CARBONYL]PHENYLALANINE
Authors:Cho, J.H., Ha, N.-C., Chung, S.J., Kim, D.H., Choi, K.Y., Oh, B.-H.
Deposit date:2000-11-17
Release date:2001-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Insight Into the Stereochemistry in the Inhibition of Carboxypeptidase a with N-(Hydroxyaminocarbonyl)Phenylalanine: Binding Modes of an Enantiomeric Pair of the Inhibitor to Carboxypeptidase A
Bioorg.Med.Chem., 10, 2002
1HEE
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CRYSTAL STRUCTURE OF BOVINE PANCREATIC CARBOXYPEPTIDASE A COMPLEXED WITH L-N-HYDROXYAMINOCARBONYL PHENYLALANINE AT 2.3 A
Descriptor:CARBOXYPEPTIDASE A, ZINC ION, L-[(N-HYDROXYAMINO)CARBONYL]PHENYLALANINE
Authors:Cho, J.H., Ha, N.-C., Chung, S.J., Kim, D.H., Choi, K.Y., Oh, B.-H.
Deposit date:2000-11-22
Release date:2001-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Insight Into the Stereochemistry in the Inhibition of Carboxypeptidase a with N-(Hydroxyaminocarbonyl)Phenylalanine: Binding Modes of an Enantiomeric Pair of the Inhibitor to Carboxypeptidase A
Bioorg.Med.Chem., 10, 2002
1IY7
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CRYSTAL STRUCTURE OF CPA AND SULFAMIDE-BASED INHIBITOR COMPLEX
Descriptor:Carboxypeptidase A, ZINC ION, PHENYLALANINE-N-SULFONAMIDE
Authors:Kim, S.J., Woo, J.R., Park, J.D., Kim, D.H., Ryu, S.E.
Deposit date:2002-07-24
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sulfamide-Based Inhibitors for Carboxypeptidase A. Novel Type Transition State Analogue Inhibitors for Zinc Proteases
J.Med.Chem., 45, 2002
1M4L
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STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION
Descriptor:CARBOXYPEPTIDASE A, ZINC ION
Authors:Kilshtain-Vardi, A., Glick, M., Greenblatt, H.M., Goldblum, A., Shoham, G.
Deposit date:2002-07-03
Release date:2003-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Refined structure of bovine carboxypeptidase A at 1.25 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
1OBR
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CARBOXYPEPTIDASE T
Descriptor:CARBOXYPEPTIDASE T, ZINC ION, CALCIUM ION, ...
Authors:Teplyakov, A., Polyakov, K., Obmolova, G., Osterman, A.
Deposit date:1996-06-22
Release date:1997-01-11
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris.
Eur.J.Biochem., 208, 1992
1YME
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STRUCTURE OF CARBOXYPEPTIDASE
Descriptor:CARBOXYPEPTIDASE A ALPHA, ZINC ION
Authors:Greenblatt, H.M., Tucker, P.A., Shoham, G.
Deposit date:1996-07-15
Release date:1997-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
1Z5R
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CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B
Descriptor:procarboxypeptidase B, ZINC ION
Authors:Adler, M., Bryant, J., Buckman, B., Islam, I., Larsen, B., Finster, S., Kent, L., May, K., Mohan, R., Yuan, S., Whitlow, M.
Deposit date:2005-03-18
Release date:2005-07-12
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG7
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CRYSTAL STRUCTURE OF 2-(5-{[AMINO(IMINO)METHYL]AMINO}-2-CHLOROPHENYL)-3-SULFANYLPROPANOIC ACID BOUND TO ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B
Descriptor:procarboxypeptidase B, ZINC ION, 2-(5-{[AMINO(IMINO)METHYL]AMINO}-2-CHLOROPHENYL)-3-SULFANYLPROPANOIC ACID
Authors:Adler, M., Bryant, J., Buckman, B., Islam, I., Larsen, B., Finster, S., Kent, L., May, K., Mohan, R., Yuan, S., Whitlow, M.
Deposit date:2005-04-20
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG8
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CRYSTAL STRUCTURE OF (R)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-SULFANYLPROPANOIC ACID BOUND TO ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B
Descriptor:procarboxypeptidase B, ZINC ION, (2R)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-SULFANYLPROPANOIC ACID
Authors:Adler, M., Bryant, J., Buckman, B., Islam, I., Larsen, B., Finster, S., Kent, L., May, K., Mohan, R., Yuan, S., Whitlow, M.
Deposit date:2005-04-20
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG9
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CRYSTAL STRUCTURE OF 5-{[AMINO(IMINO)METHYL]AMINO}-2-(SULFANYLMETHYL)PENTANOIC ACID BOUND TO ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B
Descriptor:procarboxypeptidase B, ZINC ION, 5-{[AMINO(IMINO)METHYL]AMINO}-2-(SULFANYLMETHYL)PENTANOIC ACID
Authors:Adler, M., Bryant, J., Buckman, B., Islam, I., Larsen, B., Finster, S., Kent, L., May, K., Mohan, R., Yuan, S., Whitlow, M.
Deposit date:2005-04-20
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZLH
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CRYSTAL STRUCTURE OF THE TICK CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH BOVINE CARBOXYPEPTIDASE A
Descriptor:Carboxypeptidase A1, carboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L., Popowicz, G.M., Lorenzo, J., Sommerhoff, C.P., Huber, R., Aviles, F.X., Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZLI
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CRYSTAL STRUCTURE OF THE TICK CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH HUMAN CARBOXYPEPTIDASE B
Descriptor:Carboxypeptidase B, carboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L., Popowicz, G.M., Lorenzo, J., Sommerhoff, C.P., Huber, R., Aviles, F.X., Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
2ABZ
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CRYSTAL STRUCTURE OF C19A/C43A MUTANT OF LEECH CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH BOVINE CARBOXYPEPTIDASE A
Descriptor:Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L., Popowicz, G.M., Bronsoms, S., Aviles, F.X., Huber, R., Holak, T.A., Ventura, S.
Deposit date:2005-07-18
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
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