5ZEQ
Carboxypeptidase B in complex with DD28
Summary for 5ZEQ
Entry DOI | 10.2210/pdb5zeq/pdb |
Descriptor | Carboxypeptidase B, ZINC ION, (2~{S})-2-[(6-azanyl-5-chloranyl-pyridin-3-yl)methyl]-3-selanyl-propanoic acid, ... (5 entities in total) |
Functional Keywords | selenium, organoselenium, selenol, cpb inhibitor, selectivity, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Sus scrofa (Pig) |
Total number of polymer chains | 1 |
Total formula weight | 35426.12 |
Authors | Itoh, T.,Yoshimoto, N.,Yamamoto, K. (deposition date: 2018-02-27, release date: 2018-06-20, Last modification date: 2018-07-04) |
Primary citation | Itoh, T.,Yoshimoto, N.,Hirano, Y.,Yamamoto, K. Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic group Bioorg. Med. Chem. Lett., 28:2256-2260, 2018 Cited by PubMed: 29859906DOI: 10.1016/j.bmcl.2018.05.042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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