PDB: 77 resultsInfo pagesStatus searchChemie searchBIRD

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7LF3	C1B domain of Protein kinase C in complex with diacylglycerol-lactone AJH-836 Descriptor: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... Authors: Katti, S.S, Krieger, I.V. Deposit date: 2021-01-15 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.13 Å) Cite: Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
6UWA	Mouse PKC C1B and C2 domains Descriptor: CITRIC ACID, LEAD (II) ION, Protein kinase C, ... Authors: Aggarwal, A, Mire, J, Sacchettini, J.C, Igumenova, T. Deposit date: 2019-11-04 Release date: 2020-12-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Mouse PKC C1B and C2 domains To Be Published
3UFF	Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cdelta Descriptor: PHOSPHATE ION, Protein kinase C delta type, ZINC ION Authors: Shanmugasundararaj, S, Stehle, T, Miller, K.W. Deposit date: 2011-11-01 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta Biophys.J., 103, 2012
3UEJ	Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cdelta Descriptor: PHOSPHATE ION, Protein kinase C delta type, ZINC ION Authors: Shanmugasundararaj, S, Stehle, T, Miller, K.W. Deposit date: 2011-10-30 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.301 Å) Cite: Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta Biophys.J., 103, 2012
3UEY	Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cdelta Descriptor: PHOSPHATE ION, Protein kinase C delta type, ZINC ION Authors: Shanmugasundararaj, S, Stehle, T, Miller, K.W. Deposit date: 2011-10-31 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.301 Å) Cite: Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta Biophys.J., 103, 2012
3UGL	Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta Descriptor: PHOSPHATE ION, Proteine kinase C delta type, ZINC ION, ... Authors: Shanmugasundararaj, S, Stehle, T, Miller, K.W. Deposit date: 2011-11-02 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.357 Å) Cite: Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta Biophys.J., 103, 2012
3UGI	Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta Descriptor: (methoxymethyl)cyclopropane, PHOSPHATE ION, Protein kinase C delta type, ... Authors: Shanmugasundararaj, S, Stehle, T, Miller, K.W. Deposit date: 2011-11-02 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.361 Å) Cite: Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta Biophys.J., 103, 2012
7KND	C1B domain of Protein kinase C in apo form Descriptor: Protein kinase C delta type, ZINC ION Authors: Katti, S.S, Krieger, I. Deposit date: 2020-11-04 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
3UGD	Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, Protein kinase C delta type, ... Authors: Shanmugasundararaj, S, Stehle, T, Miller, K.W. Deposit date: 2011-11-02 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta Biophys.J., 103, 2012
7KNJ	C1B domain of Protein kinase C in complex with Phorbol ester and Phosphatidylcholine Descriptor: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Phorbol 12,13-dibutyrate, Protein kinase C delta type, ... Authors: Katti, S.S, Krieger, I. Deposit date: 2020-11-04 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
4FKD	Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta Descriptor: Protein kinase C theta type, ZINC ION Authors: Rahman, G.M, Shanker, S, Lewin, N.E, Prasad, B.V.V, Blumberg, P.M, Das, J. Deposit date: 2012-06-13 Release date: 2013-01-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.633 Å) Cite: Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta. Biochem.J., 451, 2013
7LEO	C1B domain of Protein kinase C in complex with diacylglycerol-lactone (AJH-836) and 1,2-diheptanoyl-sn-glycero-3-phosphocholine Descriptor: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... Authors: Katti, S.S, Krieger, I. Deposit date: 2021-01-14 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
7LCB	C1B domain of Protein kinase C in complex with prostratin and phosphatidylcholine Descriptor: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... Authors: Katti, S.S, Krieger, I.V. Deposit date: 2021-01-10 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
7L92	C1B domain of Protein kinase C in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate Descriptor: DIACYL GLYCEROL, ETHANOL, Protein kinase C delta type, ... Authors: Katti, S.S, Krieger, I.V. Deposit date: 2021-01-01 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
7KO6	C1B domain of Protein kinase C in complex with ingenol-3-angelate and phosphocholine Descriptor: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... Authors: Katti, S.S, Krieger, I.V. Deposit date: 2020-11-06 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
2VRW	Critical structural role for the PH and C1 domains of the Vav1 exchange factor Descriptor: PROTO-ONCOGENE VAV, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, ZINC ION Authors: Rapley, J, Tybulewicz, V, Rittinger, K. Deposit date: 2008-04-16 Release date: 2008-06-17 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor. Embo Rep., 9, 2008
6XI7	Crystal Structure of wild-type KRAS (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF (crystal form I) Descriptor: CHLORIDE ION, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... Authors: Chan, A.H, Tran, T.H, Dharmaiah, S, Simanshu, D.K. Deposit date: 2020-06-19 Release date: 2021-01-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
1PTQ	PROTEIN KINASE C DELTA CYS2 DOMAIN Descriptor: PROTEIN KINASE C DELTA TYPE, ZINC ION Authors: Zhang, G, Hurley, J.H. Deposit date: 1995-05-11 Release date: 1995-07-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester. Cell(Cambridge,Mass.), 81, 1995
6XGV	Crystal Structure of KRAS-G13D (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF Descriptor: CHLORIDE ION, GLYCEROL, GTPase KRas, ... Authors: Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. Deposit date: 2020-06-18 Release date: 2021-01-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.11 Å) Cite: KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
7Z6E	Structure of the C1-PH-CNH regulatory module of MRCK1 Descriptor: Serine/threonine-protein kinase mrck-1, ZINC ION Authors: Truebestein, L, Leonard, T.A. Deposit date: 2022-03-11 Release date: 2023-02-22 Last modified: 2023-04-19 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase. Structure, 31, 2023
4B6D	Structure of the atypical C1 domain of MgcRacGAP Descriptor: GLYCEROL, RAC GTPASE-ACTIVATING PROTEIN 1, ZINC ION Authors: Pye, V.E, Lekomtsev, S, Petronczki, M, Cherepanov, P. Deposit date: 2012-08-09 Release date: 2012-12-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Centralspindlin Links the Mitotic Spindle to the Plasma Membrane During Cytokinesis. Nature, 492, 2012
1PTR	PROTEIN KINASE C DELTA CYS2 DOMAIN COMPLEXED WITH PHORBOL-13-ACETATE Descriptor: 13-ACETYLPHORBOL, PROTEIN KINASE C DELTA TYPE, ZINC ION Authors: Zhang, G, Hurley, J.H. Deposit date: 1995-05-11 Release date: 1995-07-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester. Cell(Cambridge,Mass.), 81, 1995
6RA0	A ubiquitin-like dimerization domain controls protein kinase D activation by trans-autophosphorylation Descriptor: Serine/threonine-protein kinase dkf-1, ZINC ION Authors: Elsner, D.J, Leonard, T.A. Deposit date: 2019-04-05 Release date: 2019-08-14 Last modified: 2019-10-09 Method: X-RAY DIFFRACTION (2.26 Å) Cite: A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation. J.Biol.Chem., 294, 2019
6NEW	Apo structure of the activated truncation of Vav1 Descriptor: Proto-oncogene vav, ZINC ION Authors: Knapp, M.S, Elling, R.A, Ornelas, E. Deposit date: 2018-12-18 Release date: 2019-12-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity To Be Published
6XHB	Crystal Structure of wild-type KRAS (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF (crystal form II) Descriptor: CHLORIDE ION, GLYCEROL, GTPase KRas, ... Authors: Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. Deposit date: 2020-06-18 Release date: 2021-01-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021

 

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