Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

9PAI
DownloadVisualize
BU of 9pai by Molmil
CLEAVED SUBSTRATE VARIANT OF PLASMINOGEN ACTIVATOR INHIBITOR-1
Descriptor: PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-1) residues 19-364, PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-1) residues 365-397
Authors:Aertgeerts, K, De Bondt, H.L, De Ranter, C.J, Declerck, P.J.
Deposit date:1999-03-11
Release date:1999-03-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1.
Nat.Struct.Biol., 2, 1995
9API
DownloadVisualize
BU of 9api by Molmil
THE S VARIANT OF HUMAN ALPHA1-ANTITRYPSIN, STRUCTURE AND IMPLICATIONS FOR FUNCTION AND METABOLISM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA 1-ANTITRYPSIN, ...
Authors:Loebermann, H, Tokuoka, R, Deisenhofer, J, Huber, R.
Deposit date:1988-09-08
Release date:1990-10-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism.
Protein Eng., 2, 1989
8W18
DownloadVisualize
BU of 8w18 by Molmil
The crystal structure of the Michaelis-Menten complex of a C1s/C1-INH at 3.94 Angstroms
Descriptor: Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain, Plasma protease C1 inhibitor
Authors:Garrigues, R.J, Garcia, B.L.
Deposit date:2024-02-15
Release date:2024-06-26
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (3.94 Å)
Cite:The Crystal Structure of the Michaelis-Menten Complex of C1 Esterase Inhibitor and C1s Reveals Novel Insights into Complement Regulation.
J Immunol., 213, 2024
8PI2
DownloadVisualize
BU of 8pi2 by Molmil
Native alpha-1-antitrypsin at 1.5 Angstrom (Cys232Ser)
Descriptor: 1,2-ETHANEDIOL, Alpha-1-antitrypsin, DIMETHYL SULFOXIDE, ...
Authors:Wang, M, Irving, J.A.
Deposit date:2023-06-20
Release date:2023-07-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural determinants of instability in alpha-1-antitrypsin
To Be Published
8P4U
DownloadVisualize
BU of 8p4u by Molmil
Alpha-1-antitrypsin - Sydney variant (G192C)
Descriptor: Alpha-1-antitrypsin
Authors:Kamuda, K, Lomas, D.A, Irving, J.A.
Deposit date:2023-05-23
Release date:2024-04-03
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate.
Febs J., 291, 2024
8P4J
DownloadVisualize
BU of 8p4j by Molmil
Alpha-1-antitrypsin - Sydney variant (G192C)
Descriptor: Alpha-1-antitrypsin
Authors:Kamuda, K, Lomas, D.A, Irving, J.A.
Deposit date:2023-05-22
Release date:2024-04-03
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate.
Febs J., 291, 2024
8H55
DownloadVisualize
BU of 8h55 by Molmil
The structure of zebrafish angiotensinogen
Descriptor: Angiotensinogen, SULFATE ION
Authors:Zhou, A, Wei, H.
Deposit date:2022-10-12
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:BIOLOGICAL IMPLICATIONS OF A 2 ANGSTROMS STRUCTURE OF DIMERIC ANGIOTENSINOGEN
To Be Published
8H4X
DownloadVisualize
BU of 8h4x by Molmil
Structure of cleaved Serpin B9
Descriptor: 1,2-ETHANEDIOL, Serpin B9, ZINC ION
Authors:Zhou, A, Yan, T.
Deposit date:2022-10-11
Release date:2023-10-25
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Expression, purification and crystallization of cleaved Serpin B9
To Be Published
8GXV
DownloadVisualize
BU of 8gxv by Molmil
Structure of a bacterial serpin Choloropin derived from Cholorobium limicola
Descriptor: GLYCEROL, Proteinase inhibitor I4 serpin, ZINC ION
Authors:Zhou, A, Xu, J.
Deposit date:2022-09-21
Release date:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Climpin, a Novel Bacterial a Serpin inducing a Broad Range of Proteases and Regulated by Heparin and DNA.
To Be Published
8API
DownloadVisualize
BU of 8api by Molmil
THE S VARIANT OF HUMAN ALPHA1-ANTITRYPSIN, STRUCTURE AND IMPLICATIONS FOR FUNCTION AND METABOLISM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-1 ANTITRYPSIN (CHAIN A), ...
Authors:Loebermann, H, Tokuoka, R, Deisenhofer, J, Huber, R.
Deposit date:1988-09-08
Release date:1990-10-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism.
Protein Eng., 2, 1989
7ZBF
DownloadVisualize
BU of 7zbf by Molmil
Crystal structure of native Iripin-4 serpin from tick Ixodes ricinus
Descriptor: Iripin-4 serpin, NICKEL (II) ION
Authors:Kascakova, B, Kuta Smatanova, I, Chmelar, J, Prudnikova, T.
Deposit date:2022-03-23
Release date:2023-04-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational transition of the Ixodes ricinus salivary serpin Iripin-4.
Acta Crystallogr D Struct Biol, 79, 2023
7ZAS
DownloadVisualize
BU of 7zas by Molmil
Crystal structure of cleaved Iripin-4 serpin from tick Ixodes ricinus
Descriptor: CHLORIDE ION, Iripin-4 serpin
Authors:Kascakova, B, Kuta Smatanova, I, Chmelar, J, Prudnikova, T.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational transition of the Ixodes ricinus salivary serpin Iripin-4.
Acta Crystallogr D Struct Biol, 79, 2023
7VLJ
DownloadVisualize
BU of 7vlj by Molmil
Crystal structure of Entamoeba histolytica serine protease inhibitor, Histopin, in the cleaved conformation
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, POTASSIUM ION, ...
Authors:Ali, M.F, Devi, S, Gourinath, S.
Deposit date:2021-10-03
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of Entamoeba histolytica serine protease inhibitor, Histopin, in the cleaved conformation
To Be Published
7RBW
DownloadVisualize
BU of 7rbw by Molmil
Structure of Biliverdin-binding Serpin of Boana punctata (polka-dot tree frog)
Descriptor: BILIVERDINE IX ALPHA, Biliverdin bindin serpin
Authors:Fedorov, E, Manoilov, K.Y, Verkhusha, V, Almo, S.C, Ghosh, A.
Deposit date:2021-07-06
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and Functional Characterization of a Biliverdin-Binding Near-Infrared Fluorescent Protein From the Serpin Superfamily.
J.Mol.Biol., 434, 2021
7QTZ
DownloadVisualize
BU of 7qtz by Molmil
Crystal structure of Iripin-1 serpin from tick Ixodes ricinus
Descriptor: MAGNESIUM ION, Putative salivary serpin
Authors:Kascakova, B, Kuta Smatanova, I, Chmelar, J, Prudnikova, T.
Deposit date:2022-01-17
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules.
Front Immunol, 14, 2023
7QRN
DownloadVisualize
BU of 7qrn by Molmil
Crystal structure of Ovalbumin-related protein X (OVAX) complexed with fondaparinux
Descriptor: 1,2-ETHANEDIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Ovalbumin-related protein X, ...
Authors:Coste, F, Bruneau, G, Rehault-Godbert, S.
Deposit date:2022-01-11
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Antimicrobial Proteins and Peptides in Avian Eggshell: Structural Diversity and Potential Roles in Biomineralization.
Front Immunol, 13, 2022
7QR2
DownloadVisualize
BU of 7qr2 by Molmil
Crystal structure of chicken Ovalbumin-related protein X
Descriptor: 1,2-ETHANEDIOL, Ovalbumin-related protein X, SULFATE ION
Authors:Coste, F, Rehault-Godbert, S.
Deposit date:2022-01-10
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal structure of chicken Ovalbumin-related protein X
To Be Published
7PMU
DownloadVisualize
BU of 7pmu by Molmil
Crystal structure of native Iripin-8
Descriptor: DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, Serpin-8, ...
Authors:Polderdijk, S, Kotal, J, Chmelar, J, Huntington, J.A.
Deposit date:2021-09-02
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Ixodes ricinus Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement.
Int J Mol Sci, 22, 2021
7NPL
DownloadVisualize
BU of 7npl by Molmil
ALPHA-1 ANTITRYPSIN (C232S) COMPLEXED WITH cmpd 11
Descriptor: Alpha-1-antitrypsin, GLYCEROL, N-((1S,2R)-1-(3-chloro-2-methylphenyl)-1-hydroxypentan-2-yl)-2-oxoindoline-4-carboxamide
Authors:Chung, C.
Deposit date:2021-02-27
Release date:2021-04-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The development of highly potent and selective small molecule correctors of Z alpha 1 -antitrypsin misfolding.
Bioorg.Med.Chem.Lett., 41, 2021
7NPK
DownloadVisualize
BU of 7npk by Molmil
ALPHA-1 ANTITRYPSIN C232S COMPLEXED WITH CMPD3
Descriptor: Alpha-1-antitrypsin, GLYCEROL, N-((1S,2R)-1-hydroxy-1-(o-tolyl)pentan-2-yl)-2-oxo-2,3-dihydrobenzo[d]oxazole-5-carboxamide
Authors:Chung, C.
Deposit date:2021-02-27
Release date:2021-04-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:The development of highly potent and selective small molecule correctors of Z alpha 1 -antitrypsin misfolding.
Bioorg.Med.Chem.Lett., 41, 2021
7BFI
DownloadVisualize
BU of 7bfi by Molmil
A double-histidine mutant of HSP47 slows down client release at low pH
Descriptor: 15R8 collagen model peptide, Collagen-binding protein
Authors:Oecal, S, Baumann, U.
Deposit date:2021-01-03
Release date:2021-11-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Collagen's primary structure determines collagen:HSP47 complex stoichiometry.
J.Biol.Chem., 297, 2021
7BEE
DownloadVisualize
BU of 7bee by Molmil
Crystal structure of a Hsp47-collagen peptide complex
Descriptor: 21er collagen model peptide, Collagen-binding protein
Authors:Abraham, E.T, Gebauer, J.M, Baumann, U.
Deposit date:2020-12-23
Release date:2021-11-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.939 Å)
Cite:Collagen's primary structure determines collagen:HSP47 complex stoichiometry.
J.Biol.Chem., 297, 2021
7BDU
DownloadVisualize
BU of 7bdu by Molmil
Crystal structure of a Hsp47-collagen peptide complex
Descriptor: 21er collagen model peptide, Collagen-binding protein
Authors:Abraham, E.T, Gebauer, J.M, Baumann, U.
Deposit date:2020-12-22
Release date:2021-11-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Collagen's primary structure determines collagen:HSP47 complex stoichiometry.
J.Biol.Chem., 297, 2021
7B2T
DownloadVisualize
BU of 7b2t by Molmil
Crystal structure of Iripin-5 serpin from Ixodes ricinus
Descriptor: CHLORIDE ION, MAGNESIUM ION, Serpin-4 precursor, ...
Authors:Kascakova, B, Kuta Smatanova, I.
Deposit date:2020-11-27
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus.
Acta Crystallogr D Struct Biol, 77, 2021
7AQG
DownloadVisualize
BU of 7aqg by Molmil
Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F)
Descriptor: 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid, Plasminogen activator inhibitor 1, VHH-2g-42 (Nb42), ...
Authors:Sillen, M, Strelkov, S.V, Declerck, P.J.
Deposit date:2020-10-21
Release date:2021-02-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484.
Int J Mol Sci, 22, 2021

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon