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8IVD
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BU of 8ivd by Molmil
COMPLEX STRUCTURE OF CD93-IGFBP7
Descriptor: Insulin-like growth factor-binding protein 7,Complement component C1q receptor
Authors:Xu, Y.M, Song, G.J.
Deposit date:2023-03-27
Release date:2024-01-17
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural insight into CD93 recognition by IGFBP7.
Structure, 32, 2024
8S9P
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BU of 8s9p by Molmil
1:1:1 agrin/LRP4/MuSK complex
Descriptor: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
Authors:Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
Deposit date:2023-03-29
Release date:2023-05-17
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
7QE9
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BU of 7qe9 by Molmil
Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 N34S (SPINK1 N34S)
Descriptor: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
Authors:Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
Deposit date:2021-12-01
Release date:2022-03-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7QE8
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BU of 7qe8 by Molmil
Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)
Descriptor: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
Authors:Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
Deposit date:2021-12-01
Release date:2022-03-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7E50
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BU of 7e50 by Molmil
Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
Descriptor: AAEL006007-PA, GLYCEROL, Plasminogen, ...
Authors:Varsha, A.W, Jobichen, C, Mok, Y.K.
Deposit date:2021-02-16
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor.
Protein Sci., 31, 2022
6KBR
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BU of 6kbr by Molmil
Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex
Descriptor: GLYCEROL, K41043, Kallikrein-4
Authors:Kawaguchi, Y, Nishimiya, D.
Deposit date:2019-06-26
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.
Sci Rep, 9, 2019
5YHN
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BU of 5yhn by Molmil
Solution structure of the LEKTI Domain 4
Descriptor: cDNA FLJ60407, highly similar to Serine protease inhibitor Kazal-type 5
Authors:Mok, Y.K, Ramesh, K.
Deposit date:2017-09-29
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity.
Structure, 26, 2018
2N71
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BU of 2n71 by Molmil
NMR structure of CmPI-II, a serin protease inhibitor isolated from mollusk Cenchitis muricatus
Descriptor: Protease inhibitor 2
Authors:Cabrera-Munoz, A, Rojas, L, Alonso del Rivero Antigua, M, Pires, J.
Deposit date:2015-09-01
Release date:2016-09-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of CmPI-II, a non-classical Kazal protease inhibitor: Understanding its conformational dynamics and subtilisin A inhibition.
J.Struct.Biol., 206, 2019
5DAE
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Kazal type inhibitor from salivary glands of Aedes aegypti mosquito
Descriptor: AAEL006007-PA
Authors:Torquato, R.J.S, Pereira, P.J.B, Tanaka, A.S.
Deposit date:2015-08-19
Release date:2016-09-07
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti.
Acta Crystallogr F Struct Biol Commun, 73, 2017
2N52
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BU of 2n52 by Molmil
The solution structure of the kallikrein inhibitor SPINK6
Descriptor: Serine protease inhibitor Kazal-type 6
Authors:Grotzinger, J.
Deposit date:2015-07-06
Release date:2016-03-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The solution structure of the kallikrein-related peptidases inhibitor SPINK6.
Biochem.Biophys.Res.Commun., 471, 2016
2M5X
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BU of 2m5x by Molmil
Novel method of protein purification for structural research. Example of ultra high resolution structure of SPI-2 inhibitor by X-ray and NMR spectroscopy.
Descriptor: Silk protease inhibitor 2
Authors:Lenarcic Zivkovic, M, Dvornyk, A, Kludkiewicz, B, Kopera, E, Zagorski-Ostoja, W, Grzelak, K, Zhukov, I, Bal, W.
Deposit date:2013-03-12
Release date:2014-03-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
4HGU
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BU of 4hgu by Molmil
Crystal Structure of Galleria mellonella Silk Protease Inhibitor 2
Descriptor: SODIUM ION, Silk protease inhibitor 2
Authors:Krzywda, S, Jaskolski, M, Dvornyk, A, Kludkiewicz, B, Grzelak, K, Zagorski, W, Bal, W, Kopera, E.
Deposit date:2012-10-08
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
2LEO
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BU of 2leo by Molmil
Solution structure of esophageal cancer-related gene 2
Descriptor: Serine protease inhibitor Kazal-type 7
Authors:Feng, Y, Geng, Y, Wang, J.
Deposit date:2011-06-20
Release date:2012-05-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure note: human esophageal cancer-related gene 2
J.Biomol.Nmr, 53, 2012
3TJQ
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BU of 3tjq by Molmil
N-domain of HtrA1
Descriptor: CHLORIDE ION, GLYCEROL, PLATINUM (II) ION, ...
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2011-08-24
Release date:2012-05-16
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural and Functional Analysis of HtrA1 and Its Subdomains.
Structure, 20, 2012
3QTL
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BU of 3qtl by Molmil
Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
Descriptor: Kazal-type serine protease inhibitor SPI-1, Subtilisin-like serin protease
Authors:Shenoy, R.T, Sivaraman, J.
Deposit date:2011-02-23
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for dual-inhibition mechanism of a non-classical kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin.
Plos One, 6, 2011
3PIS
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BU of 3pis by Molmil
Crystal Structure of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1
Descriptor: Kazal-type serine protease inhibitor SPI-1
Authors:Giri, P.K, Tang, X.H, Sivaraman, J.
Deposit date:2010-11-08
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin
To be Published
2KMP
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BU of 2kmp by Molmil
Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMQ
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BU of 2kmq by Molmil
Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMO
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BU of 2kmo by Molmil
Solution structure of native Leech-derived tryptase inhibitor, LDTI
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMR
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BU of 2kmr by Molmil
Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2V53
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BU of 2v53 by Molmil
Crystal structure of a SPARC-collagen complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COLLAGEN ALPHA-1(III) CHAIN, ...
Authors:Hohenester, E, Sasaki, T, Giudici, C, Farndale, R.W, Bachinger, H.P.
Deposit date:2008-10-01
Release date:2008-11-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis of Sequence-Specific Collagen Recognition by Sparc.
Proc.Natl.Acad.Sci.USA, 105, 2008
2JXD
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BU of 2jxd by Molmil
NMR structure of human Serine protease inhibitor Kazal type II (SPINK2)
Descriptor: Serine protease inhibitor Kazal-type 2
Authors:Chen, T, Lee, T.-R, Lyu, P.-C.
Deposit date:2007-11-15
Release date:2008-11-18
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Identification of trypsin-inhibitory site and structure determination of human SPINK2 serine proteinase inhibitor
Proteins, 77, 2009
2GKV
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BU of 2gkv by Molmil
Crystal structure of the SGPB:P14'-Ala32 OMTKY3-del(1-5) complex
Descriptor: Ovomucoid, Streptogrisin B
Authors:Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-04-03
Release date:2007-02-13
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007
2GKT
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BU of 2gkt by Molmil
Crystal structure of the P14'-Ala32 variant of the N-terminally truncated OMTKY3-del(1-5)
Descriptor: Ovomucoid
Authors:Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-04-03
Release date:2007-02-13
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007
2GKR
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BU of 2gkr by Molmil
Crystal structure of the N-terminally truncated OMTKY3-del(1-5)
Descriptor: CHLORIDE ION, Ovomucoid
Authors:Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-04-03
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007

 

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