PDB: 69 resultsInfo pagesStatus searchChemie searchBIRD

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8IYG	Human neuronal gap junction channel connexin 36 Descriptor: CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, Gap junction delta-2 protein Authors: Mao, W.X, Chen, S.S. Deposit date: 2023-04-04 Release date: 2024-04-10 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Assembly mechanisms of the neuronal gap junction channel connexin 36 elucidated by Cryo-EM. Arch.Biochem.Biophys., 754, 2024
2ZW3	Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution Descriptor: Gap junction beta-2 protein Authors: Maeda, S, Nakagawa, S, Suga, M, Yamashita, E, Oshima, A, Fujiyoshi, Y, Tsukihara, T. Deposit date: 2008-12-01 Release date: 2009-04-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structure of the connexin 26 gap junction channel at 3.5 A resolution Nature, 458, 2009
5ERA	Human Connexin-26 (Calcium-free) Descriptor: Gap junction beta-2 protein Authors: Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J. Deposit date: 2015-11-13 Release date: 2016-01-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.8 Å) Cite: An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. Nat Commun, 7, 2016
3IZ1	C-alpha model fitted into the EM structure of Cx26M34A Descriptor: Gap junction beta-2 protein Authors: Oshima, A, Tani, K, Toloue, M.M, Hiroaki, Y, Smock, A, Inukai, S, Cone, A, Nicholson, B.J, Sosinsky, G.E, Fujiyoshi, Y. Deposit date: 2010-08-19 Release date: 2010-11-03 Last modified: 2024-02-21 Method: ELECTRON CRYSTALLOGRAPHY (6 Å) Cite: Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels. J.Mol.Biol., 405, 2011
5ER7	Connexin-26 Bound to Calcium Descriptor: CALCIUM ION, Gap junction beta-2 protein Authors: Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J. Deposit date: 2015-11-13 Release date: 2016-01-27 Last modified: 2019-12-04 Method: X-RAY DIFFRACTION (3.286 Å) Cite: An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. Nat Commun, 7, 2016
3IZ2	C-alpha model fitted into the EM structure of Cx26M34Adel2-7 Descriptor: Gap junction beta-2 protein Authors: Oshima, A, Tani, K, Toloue, M.M, Hiroaki, Y, Smock, A, Inukai, S, Cone, A, Nicholson, B.J, Sosinsky, G.E, Fujiyoshi, Y. Deposit date: 2010-08-19 Release date: 2010-11-03 Last modified: 2024-02-21 Method: ELECTRON CRYSTALLOGRAPHY (10 Å) Cite: Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels. J.Mol.Biol., 405, 2011
6UVS	Human Connexin-26 (Low pH open conformation) Descriptor: Gap junction beta-2 protein Authors: Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M. Deposit date: 2019-11-04 Release date: 2020-04-29 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels. Cell Rep, 31, 2020
6UVR	Human Connexin-26 (Neutral pH open conformation) Descriptor: Gap junction beta-2 protein Authors: Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M. Deposit date: 2019-11-04 Release date: 2020-04-29 Last modified: 2020-05-06 Method: ELECTRON MICROSCOPY (4 Å) Cite: A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels. Cell Rep, 31, 2020
6UVT	Human Connexin-26 (Low pH closed conformation) Descriptor: Gap junction beta-2 protein Authors: Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M. Deposit date: 2019-11-04 Release date: 2020-04-29 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (7.5 Å) Cite: A Steric 'Ball-and-Chain' Mechanism for pH-Mediated Regulation of Gap Junction Channels Cell Rep, 31, 2020
8GN8	structure of human connexin 40.1 pentameric hemichannel by cryoEM Descriptor: Gap junction delta-4 protein Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: structure of human connexin 40.1 intercellular gap junction channel by cryoEM To Be Published
8GN7	structure of human connexin 40.1 intercellular gap junction channel by cryoEM Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, Gap junction delta-4 protein, ... Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3 Å) Cite: structure of human connexin 40.1 intercellular gap junction channel by cryoEM To Be Published
8GNB	structure of human connexin 40.1 side-by-side decamer channel by cryoEM Descriptor: Gap junction delta-4 protein Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: structure of human connexin 40.1 side-by-side decamer channel by cryoEM To Be Published
8HKP	Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry) Descriptor: Gap junction delta-2 protein, Lauryl Maltose Neopentyl Glycol Authors: Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. Deposit date: 2022-11-27 Release date: 2023-03-22 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
6L3T	Human Cx31.3/GJC3 connexin hemichannel in the absence of calcium Descriptor: Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol Authors: Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. Deposit date: 2019-10-15 Release date: 2020-09-09 Last modified: 2020-10-14 Method: ELECTRON MICROSCOPY (2.34 Å) Cite: Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
6L3V	The R15G mutant of human Cx31.3/GJC3 connexin hemichannel Descriptor: Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol Authors: Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. Deposit date: 2019-10-15 Release date: 2020-09-09 Last modified: 2020-10-14 Method: ELECTRON MICROSCOPY (2.63 Å) Cite: Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
6L3U	Human Cx31.3/GJC3 connexin hemichannel in the presence of calcium Descriptor: CALCIUM ION, Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol Authors: Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. Deposit date: 2019-10-15 Release date: 2020-09-09 Last modified: 2020-10-14 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
6MHQ	Structure of connexin-46 intercellular gap junction channel at 3.4 angstrom resolution by cryoEM Descriptor: Gap junction alpha-3 protein, connexin-46 Authors: Myers, J.B, Reichow, S.L. Deposit date: 2018-09-18 Release date: 2018-12-12 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of native lens connexin 46/50 intercellular channels by cryo-EM. Nature, 564, 2018
8QA2	Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8QA1	Cryo-EM structure of Cx26 solubilised in LMNG - Hemichannel classification NFlex conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8Q9Z	Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel) Descriptor: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8QA3	Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; NFlex conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8QA0	Cryo-EM structure of Cx26 solubilised in LMNG - hemichannel classification - NConst conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
8R7Q	human connexin-36 gap junction channel in complex with quinine Descriptor: Gap junction delta-2 protein, Quinine Authors: Ding, X.Y, Blum, T.B, Korkhov, V.M. Deposit date: 2023-11-27 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: Structural basis of connexin-36 gap junction channel inhibition. Cell Discov, 10, 2024
8R7P	human connexin-36 gap junction channel Descriptor: Gap junction delta-2 protein Authors: Ding, X.Y, Blum, T.B, Korkhov, V.M. Deposit date: 2023-11-27 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Structural basis of connexin-36 gap junction channel inhibition. Cell Discov, 10, 2024
8QOJ	human connexin-36 gap junction channel in complex with mefloquine Descriptor: Gap junction delta-2 protein, Mefloquine Authors: Ding, X.Y, Blum, T.B, Korkhov, V.M. Deposit date: 2023-09-29 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (2.13 Å) Cite: Structural basis of connexin-36 gap junction channel inhibition. Cell Discov, 10, 2024

 

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