8HKP

Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry)

Summary for 8HKP

• Entry DOI: 10.2210/pdb8hkp/pdb
• EMDB information: 34856
• Descriptor: Gap junction delta-2 protein, Lauryl Maltose Neopentyl Glycol (2 entities in total)
• Functional Keywords: connexin 36, cx36, gap junction channel, gjd2, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 454988.77

Authors

Lee, S.N.,Cho, H.J.,Jeong, H.,Ryu, B.,Lee, H.J.,Lee, H.H.,Woo, J.S. (deposition date: 2022-11-27, release date: 2023-03-22, Last modification date: 2023-12-13)

• Primary citation: Lee, S.N.,Cho, H.J.,Jeong, H.,Ryu, B.,Lee, H.J.,Kim, M.,Yoo, J.,Woo, J.S.,Lee, H.H.; Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.; Nat Commun, 14:1347-1347, 2023; PubMed: 36906653; DOI: 10.1038/s41467-023-37040-8

Experimental method

ELECTRON MICROSCOPY (3.6 Å)