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4M63
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BU of 4m63 by Molmil
Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
Authors:Tomchick, D.R, Zahm, J.A, Rosen, M.K.
Deposit date:2013-08-08
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
4CJ7
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BU of 4cj7 by Molmil
Structure of Crenactin, an archeal actin-like protein
Descriptor: ACTIN/ACTIN FAMILY PROTEIN, ADENOSINE-5'-DIPHOSPHATE
Authors:Izore, T, Duman, R.E, Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2013-12-19
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crenactin from Pyrobaculum Calidifontis is Closely Related to Actin in Structure and Forms Steep Helical Filaments.
FEBS Lett., 588, 2014
3J8I
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BU of 3j8i by Molmil
Near-Atomic Resolution for One State of F-Actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Galkin, V.E.
Deposit date:2014-11-06
Release date:2015-01-14
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Near-atomic resolution for one state of f-actin.
Structure, 23, 2015
1LCU
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BU of 1lcu by Molmil
Polylysine Induces an Antiparallel Actin Dimer that Nucleates Filament Assembly: Crystal Structure at 3.5 A Resolution
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Bubb, M.R, Govindasamy, L, Yarmola, E.G, Vorobiev, S.M, Almo, S.C, Somasundaram, T, Chapman, M.S, Agbandje-Mckenna, M, Mckenna, R.
Deposit date:2002-04-06
Release date:2002-05-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
J.Biol.Chem., 277, 2002
3QB0
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BU of 3qb0 by Molmil
Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION
Authors:Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P.
Deposit date:2011-01-12
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.404 Å)
Cite:Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin.
Embo J., 30, 2011
1WUA
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BU of 1wua by Molmil
The structure of Aplyronine A-actin complex
Descriptor: (8R,9R,10R,11R,14S,18S,20S,24S)-24-{(1R,2S,3R,6R,7R,8R,9S,10E)-8-(ACETYLOXY)-6-[(N,N-DIMETHYLALANYL)OXY]-11-[FORMYL(MET HYL)AMINO]-2-HYDROXY-1,3,7,9-TETRAMETHYLUNDEC-10-ENYL}-10-HYDROXY-14,20-DIMETHOXY-9,11,15,18-TETRAMETHYL-2-OXOOXACYCLOTE TRACOSA-3,5,15,21-TETRAEN-8-YL N,N,O-TRIMETHYLSERINATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Hirata, K, Muraoka, S, Suenaga, K, Kuroda, T, Kato, K, Tanaka, H, Yamamoto, M, Takata, M, Yamada, K, Kigoshi, H.
Deposit date:2004-12-03
Release date:2006-02-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure basis for antitumor effect of aplyronine a
J.Mol.Biol., 356, 2006
4WYB
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BU of 4wyb by Molmil
Structure of the Bud6 flank domain in complex with actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Eck, M.J, Park, E, Zheng, W.
Deposit date:2014-11-17
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.493 Å)
Cite:Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif.
Structure, 23, 2015
5LY3
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BU of 5ly3 by Molmil
P. calidifontis crenactin in complex with arcadin-2 C-terminal peptide
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein, Actin/actin family protein
Authors:Izore, T, Lowe, J.
Deposit date:2016-09-23
Release date:2016-11-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crenactin forms actin-like double helical filaments regulated by arcadin-2.
Elife, 5, 2016
6WVT
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BU of 6wvt by Molmil
Structural basis of alphaE-catenin - F-actin catch bond behavior
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Xu, X.P, Pokutta, S, Torres, M, Swift, M.F, Hanein, D, Volkmann, N, Weis, W.I.
Deposit date:2020-05-06
Release date:2020-10-07
Last modified:2025-04-02
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural basis of alpha E-catenin-F-actin catch bond behavior.
Elife, 9, 2020
5MW1
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BU of 5mw1 by Molmil
cryoEM structure of crenactin double helical filament at 3.8A resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin/actin family protein
Authors:Izore, T, Lowe, J.
Deposit date:2017-01-17
Release date:2017-02-08
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Crenactin forms actin-like double helical filaments regulated by arcadin-2.
Elife, 5, 2016
5MVA
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BU of 5mva by Molmil
Structure of the thin filament at high calcium concentration
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle
Authors:Paul, D.M, Squire, J.M, Morris, E.P.
Deposit date:2017-01-16
Release date:2017-11-29
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (27.700001 Å)
Cite:Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism.
J. Struct. Biol., 197, 2017
5JLF
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BU of 5jlf by Molmil
Structure of the F-actin-tropomyosin complex (Reprocessed)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:von der Ecken, J, Raunser, S.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.
Nature, 534, 2016
6QRI
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BU of 6qri by Molmil
Structure of rabbit G-actin in complex with chivosazole A
Descriptor: (2~{R},3~{R},5~{S},6~{E},8~{E},10~{Z},12~{S},13~{R},16~{Z},18~{E},20~{Z},22~{E},24~{R},25~{S},26~{E},28~{Z})-13-[(2~{S},3~{S},5~{S})-3,5-bis(oxidanyl)hexan-2-yl]-25-[(2~{R},3~{R},4~{S},5~{R},6~{R})-3,4-dimethoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-3-methoxy-2,12,22,24-tetramethyl-5-oxidanyl-14,32-dioxa-33-azabicyclo[28.2.1]tritriaconta-1(33),6,8,10,16,18,20,22,26,28,30-undecaen-15-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Schneider, S, Wang, S, Zahler, S.
Deposit date:2019-02-19
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Chivosazole A Modulates Protein-Protein Interactions of Actin.
J.Nat.Prod., 82, 2019
9B3R
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BU of 9b3r by Molmil
The structure of human cardiac F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A.
Deposit date:2024-03-20
Release date:2024-05-29
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The hypertrophic cardiomyopathy-associated A331P actin variant enhances basal contractile activity and elicits resting muscle dysfunction.
Iscience, 28, 2025
9B3Q
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BU of 9b3q by Molmil
The structure of the human cardiac F-actin mutant A331P
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A.
Deposit date:2024-03-20
Release date:2024-05-29
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of human cardiac actin
To Be Published
6T24
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BU of 6t24 by Molmil
Cryo-EM structure of jasplakinolide-stabilized F-actin (aged)
Descriptor: (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
Authors:Pospich, S, Merino, F, Raunser, S.
Deposit date:2019-10-07
Release date:2020-03-04
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments.
Structure, 28, 2020
6T20
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BU of 6t20 by Molmil
Cryo-EM structure of phalloidin-stabilized F-actin (aged)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Pospich, S, Merino, F, Raunser, S.
Deposit date:2019-10-07
Release date:2020-03-04
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments.
Structure, 28, 2020
1J6Z
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BU of 1j6z by Molmil
UNCOMPLEXED ACTIN
Descriptor: ACTIN ALPHA 1, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Otterbein, L.R, Graceffa, P, Dominguez, R.
Deposit date:2001-05-15
Release date:2001-08-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The crystal structure of uncomplexed actin in the ADP state.
Science, 293, 2001
1IJJ
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BU of 1ijj by Molmil
THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Vorobiev, S.M, Bubb, M.R, Almo, S.C.
Deposit date:2001-04-26
Release date:2002-04-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution
J.Biol.Chem., 277, 2002
7K21
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BU of 7k21 by Molmil
Cryo-EM structure of pyrene-labeled ADP-Pi-actin filaments
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chou, S.Z, Pollard, T.D.
Deposit date:2020-09-08
Release date:2020-11-04
Last modified:2025-04-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-electron microscopy structures of pyrene-labeled ADP-P i - and ADP-actin filaments.
Nat Commun, 11, 2020
7K20
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BU of 7k20 by Molmil
Cryo-EM structure of pyrene-labeled ADP-actin filaments
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chou, S.Z, Pollard, T.D.
Deposit date:2020-09-08
Release date:2020-11-04
Last modified:2025-04-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-electron microscopy structures of pyrene-labeled ADP-P i - and ADP-actin filaments.
Nat Commun, 11, 2020
8R3H
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BU of 8r3h by Molmil
Phalloidin bound F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Yuan, B, Paraschiakos, T, Windhorst, S, Marlovits, T.C.
Deposit date:2023-11-09
Release date:2025-05-21
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Phalloidin bound F-actin
To Be Published
8RU0
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BU of 8ru0 by Molmil
Structure of the undecorated barbed end of F-actin.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P.
Deposit date:2024-01-29
Release date:2024-04-10
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
6MGO
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BU of 6mgo by Molmil
Structure of rabbit actin in complex with Mycalolide B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Allingham, J.S, Trofimova, D.
Deposit date:2018-09-14
Release date:2018-11-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Truncated Actin-Targeting Macrolide Derivative Blocks Cancer Cell Motility and Invasion of Extracellular Matrix.
J.Am.Chem.Soc., 2021
7BTI
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BU of 7bti by Molmil
Phalloidin bound F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kumari, A, Ragunath, V.K, Sirajuddin, M.
Deposit date:2020-04-01
Release date:2020-05-20
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into actin filament recognition by commonly used cellular actin markers.
Embo J., 39, 2020

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PDB entries from 2025-07-09

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