1A3P
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ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES
Descriptor:EPIDERMAL GROWTH FACTOR
Authors:Barnham, K., Torres, A., Alewood, D., Alewood, P., Domagala, T., Nice, E., Norton, R.
Deposit date:1998-01-22
Release date:1998-07-29
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
1APO
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THREE-DIMENSIONAL STRUCTURE OF THE APO FORM OF THE N-TERMINAL EGF-LIKE MODULE OF BLOOD COAGULATION FACTOR X AS DETERMINED BY NMR SPECTROSCOPY AND SIMULATED FOLDING
Descriptor:EGF-LIKE MODULE OF BLOOD COAGULATION FACTOR X (N-TERMINAL, APO FORM) (NMR, 13 STRUCTURES)
Authors:Ullner, M., Selander, M., Persson, E., Stenflo, J., Drakenberg, T., Teleman, O.
Deposit date:1992-04-21
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional structure of the apo form of the N-terminal EGF-like module of blood coagulation factor X as determined by NMR spectroscopy and simulated folding.
Biochemistry, 31, 1992
1BF9
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N-TERMINAL EGF-LIKE DOMAIN FROM HUMAN FACTOR VII, NMR, 23 STRUCTURES
Descriptor:FACTOR VII
Authors:Muranyi, A., Finn, B.E., Gippert, G.P., Forsen, S., Stenflo, J., Drakenberg, T.
Deposit date:1998-05-28
Release date:1999-02-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal EGF-like domain from human factor VII.
Biochemistry, 37, 1998
1CCF
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HOW AN EPIDERMAL GROWTH FACTOR (EGF)-LIKE DOMAIN BINDS CALCIUM-HIGH RESOLUTION NMR STRUCTURE OF THE CALCIUM FORM OF THE NH2-TERMINAL EGF-LIKE DOMAIN IN COAGULATION FACTOR X
Descriptor:COAGULATION FACTOR X (THE CALCIUM FORM OF THE N-TERMINAL EGF-LIKE MODULE) (NMR, 15 STRUCTURES)
Authors:Selander-Sunnerhagen, M., Ullner, M., Persson, M., Teleman, O., Stenflo, J., Drakenberg, T.
Deposit date:1993-05-19
Release date:1994-05-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2-terminal EGF-like domain in coagulation factor X.
J.Biol.Chem., 267, 1992
1EDM
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EPIDERMAL GROWTH FACTOR-LIKE DOMAIN FROM HUMAN FACTOR IX
Descriptor:FACTOR IX
Authors:Rao, Z., Handford, P., Mayhew, M., Knott, V., Brownlee, G.G., Stuart, D.
Deposit date:1996-03-21
Release date:1996-10-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structure of a Ca(2+)-binding epidermal growth factor-like domain: its role in protein-protein interactions.
Cell(Cambridge,Mass.), 82, 1995
1EGF
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SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY MINIMIZATION WITH RESTRAINTS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) (NMR, 16 STRUCTURES)
Authors:Montelione, G.T., Wuthrich, K., Scheraga, H.A.
Deposit date:1991-10-01
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints.
Biochemistry, 31, 1992
1EPG
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THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 2 SOLUTION (NMR, MINIMIZED MEAN STRUCTURE)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1EPH
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THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 2 SOLUTION (NMR, 10 STRUCTURES)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1EPI
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THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 6.8 SOLUTION (NMR, MINIMIZED MEAN STRUCTURE)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1EPJ
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THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 6.8 SOLUTION (NMR, 5 STRUCTURES)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1F7E
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, 20 STRUCTURES
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1F7M
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII, MINIMIZED
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FF7
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, 20 STRUCTURES
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII (FUCOSYLATED)
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FFM
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII (FUCOSYLATED)
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1HAE
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HEREGULIN-ALPHA EPIDERMAL GROWTH FACTOR-LIKE DOMAIN, NMR, 20 STRUCTURES
Descriptor:HEREGULIN-ALPHA
Authors:Jacobsen, N.E., Skelton, N.J., Fairbrother, W.J.
Deposit date:1995-11-30
Release date:1996-07-11
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:High-resolution solution structure of the EGF-like domain of heregulin-alpha.
Biochemistry, 35, 1996
1HAF
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HEREGULIN-ALPHA EPIDERMAL GROWTH FACTOR-LIKE DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:HEREGULIN-ALPHA
Authors:Jacobsen, N.E., Skelton, N.J., Fairbrother, W.J.
Deposit date:1995-11-30
Release date:1996-07-11
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:High-resolution solution structure of the EGF-like domain of heregulin-alpha.
Biochemistry, 35, 1996
1HRE
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SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4
Descriptor:HEREGULIN-ALPHA (EPIDERMAL GROWTH FACTOR-LIKE DOMAIN) (NMR, MINIMIZED AVERAGE STRUCTURE)
Authors:Nagata, K., Kohda, D., Hatanaka, H., Ichikawa, S., Inagaki, F.
Deposit date:1994-07-21
Release date:1994-10-15
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.
EMBO J., 13, 1994
1HRF
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SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4
Descriptor:HEREGULIN-ALPHA (EPIDERMAL GROWTH FACTOR-LIKE DOMAIN) (NMR, 10 STRUCTURES)
Authors:Nagata, K., Kohda, D., Hatanaka, H., Ichikawa, S., Inagaki, F.
Deposit date:1994-07-21
Release date:1994-10-15
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.
EMBO J., 13, 1994
1IXA
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THE THREE-DIMENSIONAL STRUCTURE OF THE FIRST EGF-LIKE MODULE OF HUMAN FACTOR IX: COMPARISON WITH EGF AND TGF-A
Descriptor:EGF-LIKE MODULE OF HUMAN FACTOR IX (NMR, MINIMIZED AVERAGE STRUCTURE)
Authors:Baron, M., Norman, D.G., Harvey, T.S., Hanford, P.A., Mayhew, M., Tse, A.G.D., Brownlee, G.G., Campbell, I.D.C.
Deposit date:1991-11-14
Release date:1993-10-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha.
Protein Sci., 1, 1992
1JL9
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CRYSTAL STRUCTURE OF HUMAN EPIDERMAL GROWTH FACTOR
Descriptor:EPIDERMAL GROWTH FACTOR
Authors:Lu, H.S., Chai, J.J., Li, M., Huang, B.R., He, C.H., Bi, R.C.
Deposit date:2001-07-16
Release date:2001-10-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human epidermal growth factor and its dimerization
J.Biol.Chem., 276, 2001
2KV4
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EGF
Descriptor:Epidermal growth factor
Authors:Huang, H.W., Mohan, S.K., Yu, C.
Deposit date:2010-03-08
Release date:2011-02-23
Method:SOLUTION NMR
Cite:The NMR solution structure of human epidermal growth factor (hEGF) at physiological pH and its interactions with suramin
Biochem.Biophys.Res.Commun., 402, 2010
2VJ2
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HUMAN JAGGED-1, DOMAINS DSL AND EGFS1-3
Descriptor:JAGGED-1
Authors:Johnson, S., Cordle, J., Tay, J.Z., Roversi, P., Handford, P.A., Lea, S.M.
Deposit date:2007-12-06
Release date:2008-07-29
Modification date:2010-08-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
3EGF
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SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY MINIMIZATION WITH RESTRAINTS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) (NMR, 16 STRUCTURES AFTER ENERGY MINIMIZATION)
Authors:Montelione, G.T., Wuthrich, K., Scheraga, H.A.
Deposit date:1992-08-30
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints.
Biochemistry, 31, 1992
4Z6A
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CRYSTAL STRUCTURE OF A FVIIA-TRYPSIN CHIMERA (YT) IN COMPLEX WITH SOLUBLE TISSUE FACTOR
Descriptor:BLOOD COAGULATION FACTOR VIIA LIGHT CHAIN (E.C.EC: 3.4.21.21), BLOOD COAGULATION FACTOR VIIA HEAVY CHAIN, SOLUBLE TISSUE FACTOR (E.C.EC: 3.4.21.21)
Authors:Sorensen, A.B., Svensson, L.A., Gandhi, P.S.
Deposit date:2015-04-04
Release date:2015-12-30
Modification date:2016-12-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity.
J.Biol.Chem., 291, 2016
5BO1
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CRYSTAL STRUCTURE OF A HUMAN JAG1 FRAGMENT IN COMPLEX WITH AN ANTI-JAG1 FAB
Descriptor:Protein jagged-1, Fab heavy chain, Fab light chain
Authors:Payandeh, J., de Leon-Boenig, G.
Deposit date:2015-05-26
Release date:2015-11-18
Modification date:2015-12-16
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Nature, 528, 2015
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