1P9J

Solution structure and dynamics of the EGF/TGF-alpha chimera T1E

Summary for 1P9J

Descriptorchimera of Epidermal growth factor(EGF) and Transforming growth factor alpha (TGF-alpha) (1 entity in total)
Functional Keywordschimera, egf, tgf-alpha, erbb1, erbb3, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight6339.22
Authors
Wingens, M.,Walma, T.,Van Ingen, H.,Stortelers, C.,Van Leeuwen, J.E.,Van Zoelen, E.J.,Vuister, G.W. (deposition date: 2003-05-12, release date: 2003-10-07, Last modification date: 2020-02-05)
Primary citation
Wingens, M.,Walma, T.,Van Ingen, H.,Stortelers, C.,Van Leeuwen, J.E.,Van Zoelen, E.J.,Vuister, G.W.
Structural Analysis of an Epidermal Growth Factor/Transforming Growth Factor-alpha Chimera with Unique ErbB Binding Specificity.
J.Biol.Chem., 278:39114-39123, 2003
PubMed: 12869572 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M305603200
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers0 1.6% 5.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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171916
PDB entries from 2020-12-02