8QCB
| CryoEM structure of a S. Cerevisiae Ski2387 complex in the open state | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, Superkiller protein 3, ... | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | Deposit date: | 2023-08-25 | Release date: | 2023-11-08 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
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8QCA
| CryoEM structure of a S. Cerevisiae Ski2387 complex in the closed state bound to RNA | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | Deposit date: | 2023-08-25 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
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8Q9T
| CryoEM structure of a S. Cerevisiae Ski238 complex bound to RNA | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | Deposit date: | 2023-08-21 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
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8J8Q
| Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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8J8P
| Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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8OEW
| Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | Deposit date: | 2023-03-13 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8OF0
| Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | Deposit date: | 2023-03-13 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8OEU
| Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | Deposit date: | 2023-03-13 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8OEV
| Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure, structure 3) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | Deposit date: | 2023-03-13 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8A40
| Structure of mammalian Pol II-TFIIS elongation complex | Descriptor: | DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | Authors: | Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. | Deposit date: | 2022-06-09 | Release date: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
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7XTI
| RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-17 | Release date: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XTD
| RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-16 | Release date: | 2022-09-07 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XT7
| RNA polymerase II elongation complex transcribing a nucleosome (EC49B) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-16 | Release date: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XSZ
| RNA polymerase II elongation complex transcribing a nucleosome (EC115) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-15 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XSX
| RNA polymerase II elongation complex transcribing a nucleosome (EC49) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-15 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XSE
| RNA polymerase II elongation complex transcribing a nucleosome (EC42) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-13 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XN7
| RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C | Descriptor: | Chromatin elongation factor SPT5, Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-04-28 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7UND
| Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | Authors: | Filipovski, M, Vos, S.M, Farnung, L. | Deposit date: | 2022-04-10 | Release date: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of nucleosome retention during transcription elongation. Science, 376, 2022
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7UNC
| Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | Authors: | Filipovski, M, Vos, S.M, Farnung, L. | Deposit date: | 2022-04-10 | Release date: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of nucleosome retention during transcription elongation. Science, 376, 2022
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7QDZ
| 80S-bound human SKI complex in the closed state | Descriptor: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-12-01 | Release date: | 2022-02-09 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDY
| RNA-bound human SKI complex | Descriptor: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-12-01 | Release date: | 2022-02-09 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDS
| Apo human SKI complex in the open state | Descriptor: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | Authors: | Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. | Deposit date: | 2021-11-30 | Release date: | 2022-02-02 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7QDR
| Apo human SKI complex in the closed state | Descriptor: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-11-29 | Release date: | 2022-02-02 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7PKS
| Structural basis of Integrator-mediated transcription regulation | Descriptor: | DNA Template, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Fianu, I, Chen, Y, Dienemann, C, Cramer, P. | Deposit date: | 2021-08-26 | Release date: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of Integrator-mediated transcription regulation. Science, 374, 2021
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7V2Y
| cryo-EM structure of yeast THO complex with Sub2 | Descriptor: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ... | Authors: | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2021-08-10 | Release date: | 2022-07-27 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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