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5ZYP
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BU of 5zyp by Molmil
Structure of the Yeast Ctr9/Paf1 complex
Descriptor: NICKEL (II) ION, RNA polymerase-associated protein CTR9,RNA polymerase II-associated protein 1
Authors:Xie, Y, Zheng, M, Zhou, H, Long, J.
Deposit date:2018-05-28
Release date:2018-09-26
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
5ZYQ
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BU of 5zyq by Molmil
The Structure of Human PAF1/CTR9 complex
Descriptor: RNA polymerase-associated protein CTR9 homolog,RNA polymerase II-associated factor 1 homolog
Authors:Xie, Y, Zheng, M, Zhou, H, Long, J.
Deposit date:2018-05-28
Release date:2018-09-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.531 Å)
Cite:Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
7DKH
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BU of 7dkh by Molmil
Crystal structure of the Ctr9/Paf1/Cdc73/Rtf1 quaternary complex
Descriptor: Cell division control protein 73, RNA polymerase II-associated protein 1, RNA polymerase-associated protein CTR9, ...
Authors:Chen, F.L, Liu, B.B, Guo, L, Li, D.F, Zhou, H, Long, J.F.
Deposit date:2020-11-24
Release date:2021-11-24
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Core Module of the Yeast Paf1 Complex.
J.Mol.Biol., 434, 2021
4M6T
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BU of 4m6t by Molmil
Structure of human Paf1 and Leo1 complex
Descriptor: RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ...
Authors:Shen, Y, Qin, X.
Deposit date:2013-08-11
Release date:2013-10-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structural insights into Paf1 complex assembly and histone binding
Nucleic Acids Res., 41, 2013
6AF0
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BU of 6af0 by Molmil
Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila
Descriptor: Cdc73 protein, Ctr9 protein, Paf1 protein
Authors:Wang, Z, Deng, P, Zhou, Y.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8J8Q
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BU of 8j8q by Molmil
Structure of the four-component Paf1 complex from Saccharomyces eubayanus
Descriptor: CDC73-like protein, CTR9-like protein, PAF1-like protein, ...
Authors:Wang, Z, Qin, Y, Zhou, Y, Cao, Y.
Deposit date:2023-05-02
Release date:2023-05-24
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus .
Int J Mol Sci, 24, 2023
8J8P
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BU of 8j8p by Molmil
Structure of the four-component Paf1 complex from Saccharomyces eubayanus
Descriptor: CDC73-like protein, CTR9-like protein, PAF1-like protein, ...
Authors:Wang, Z, Qin, Y, Zhou, Y, Cao, Y.
Deposit date:2023-05-02
Release date:2023-05-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus .
Int J Mol Sci, 24, 2023
6IIW
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BU of 6iiw by Molmil
Crystal structure of human UHRF1 PHD finger in complex with PAF15
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase UHRF1, PCNA-associated factor, ...
Authors:Arita, K, Kori, S.
Deposit date:2018-10-07
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
Nat Commun, 11, 2020
3V46
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BU of 3v46 by Molmil
Crystal Structure of Yeast Cdc73 C-Terminal Domain
Descriptor: Cell division control protein 73
Authors:Amrich, C.G, VanDemark, A.P.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin.
J.Biol.Chem., 287, 2012
8A3Y
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BU of 8a3y by Molmil
Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P.
Deposit date:2022-06-09
Release date:2024-07-31
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Mol.Cell, 82, 2022
6GMH
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BU of 6gmh by Molmil
Structure of activated transcription complex Pol II-DSIF-PAF-SPT6
Descriptor: CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ...
Authors:Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P.
Deposit date:2018-05-26
Release date:2018-08-22
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
5E8B
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BU of 5e8b by Molmil
Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R126A
Descriptor: BENZAMIDINE, RNA polymerase-associated protein RTF1, SODIUM ION
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2015-10-14
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol. Cell, 64, 2016
5EMX
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BU of 5emx by Molmil
Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R124A R126A R128A
Descriptor: RNA polymerase-associated protein RTF1
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2015-11-06
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol.Cell, 64, 2016
4L1P
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BU of 4l1p by Molmil
Crystal Structure of Human Rtf1 Plus3 domain
Descriptor: GLYCEROL, RNA polymerase-associated protein RTF1 homolog
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L1U
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BU of 4l1u by Molmil
Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide
Descriptor: GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ...
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.424 Å)
Cite:Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
7XN7
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BU of 7xn7 by Molmil
RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C
Descriptor: Chromatin elongation factor SPT5, Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-04-28
Release date:2022-09-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
9EGY
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BU of 9egy by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Markert, J, Farnung, L.
Deposit date:2024-11-21
Release date:2024-12-18
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EGX
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BU of 9egx by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-hexasome, bp +27
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Markert, J, Farnung, L.
Deposit date:2024-11-21
Release date:2024-12-18
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EGZ
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BU of 9egz by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, bp +27
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Markert, J.W, Farnung, L.
Deposit date:2024-11-21
Release date:2024-12-18
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EH0
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BU of 9eh0 by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 30 bp upstream
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Markert, J, Farnung, L.
Deposit date:2024-11-21
Release date:2024-12-18
Last modified:2025-02-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
9EH2
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BU of 9eh2 by Molmil
RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstream
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Markert, J, Farnung, L.
Deposit date:2024-11-21
Release date:2024-12-18
Last modified:2025-02-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription.
Science, 387, 2025
7UND
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BU of 7und by Molmil
Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Filipovski, M, Vos, S.M, Farnung, L.
Deposit date:2022-04-10
Release date:2022-10-19
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of nucleosome retention during transcription elongation.
Science, 376, 2022
7UNC
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BU of 7unc by Molmil
Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Filipovski, M, Vos, S.M, Farnung, L.
Deposit date:2022-04-10
Release date:2022-10-19
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of nucleosome retention during transcription elongation.
Science, 376, 2022
7FAW
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BU of 7faw by Molmil
Structure of LW domain from Yeast
Descriptor: Transcription elongation factor S-II
Authors:Liao, S, Gao, J, Tu, X.
Deposit date:2021-07-07
Release date:2022-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.438 Å)
Cite:Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
7FAX
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BU of 7fax by Molmil
Complex structure of TbLeo1 and LW domain from Trypanosoma brucei
Descriptor: TbLW, TbLeo1 peptide
Authors:Liao, S, Gao, J, Tu, X.
Deposit date:2021-07-07
Release date:2022-07-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023

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