5ZYP | | STRUCTURE OF THE YEAST CTR9/PAF1 COMPLEX | | Descriptor: | RNA polymerase-associated protein CTR9,RNA polymerase II-associated protein 1, NICKEL (II) ION | | Authors: | Xie, Y., Zheng, M., Zhou, H., Long, J. | | Deposit date: | 2018-05-28 | | Release date: | 2018-09-26 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (2.532 Å) | | Cite: | Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
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5ZYQ | | THE STRUCTURE OF HUMAN PAF1/CTR9 COMPLEX | | Descriptor: | RNA polymerase-associated protein CTR9 homolog,RNA polymerase II-associated factor 1 homolog | | Authors: | Xie, Y., Zheng, M., Zhou, H., Long, J. | | Deposit date: | 2018-05-28 | | Release date: | 2018-09-26 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (2.531 Å) | | Cite: | Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
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4M6T | | STRUCTURE OF HUMAN PAF1 AND LEO1 COMPLEX | | Descriptor: | RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ... | | Authors: | Shen, Y., Qin, X. | | Deposit date: | 2013-08-11 | | Release date: | 2013-10-02 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (2.498 Å) | | Cite: | Structural insights into Paf1 complex assembly and histone binding
Nucleic Acids Res., 41, 2013
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6AF0 | | STRUCTURE OF CTR9, PAF1 AND CDC73 TERNARY COMPLEX FROM MYCELIOPHTHORA THERMOPHILA | | Descriptor: | Ctr9 protein, Paf1 protein, Cdc73 protein | | Authors: | Wang, Z., Deng, P., Zhou, Y. | | Deposit date: | 2018-08-07 | | Release date: | 2018-09-19 | | Last modified: | 2018-10-17 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3V46 | | CRYSTAL STRUCTURE OF YEAST CDC73 C-TERMINAL DOMAIN | | Descriptor: | Cell division control protein 73 | | Authors: | Amrich, C.G., VanDemark, A.P. | | Deposit date: | 2011-12-14 | | Release date: | 2012-02-15 | | Last modified: | 2013-07-03 | | Method: | X-RAY DIFFRACTION (1.549 Å) | | Cite: | Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin.
J.Biol.Chem., 287, 2012
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6GMH | | STRUCTURE OF ACTIVATED TRANSCRIPTION COMPLEX POL II-DSIF-PAF-SPT6 | | Descriptor: | RPB1, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit C, ... | | Authors: | Vos, S.M., Farnung, L., Boehing, M., Linden, A., Wigge, C., Urlaub, H., Cramer, P. | | Deposit date: | 2018-05-26 | | Release date: | 2018-08-22 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
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4L1P | |
4L1U | | CRYSTAL STRUCTURE OF HUMAN RTF1 PLUS3 DOMAIN IN COMPLEX WITH SPT5 CTR PHOSPHOPEPTIDE | | Descriptor: | RNA polymerase-associated protein RTF1 homolog, Transcription elongation factor SPT5, SULFATE ION, ... | | Authors: | Wier, A.D., Heroux, A., VanDemark, A.P. | | Deposit date: | 2013-06-03 | | Release date: | 2013-10-02 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.424 Å) | | Cite: | Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
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5E8B | |
5EMX | |
2DB9 | | SOLUTION STRUCTURE OF THE PLUS-3 DOMAIN OF HUMAN KIAA0252 PROTEIN | | Descriptor: | Paf1/RNA polymerase II complex component | | Authors: | Yoneyama, M., Kigawa, T., Tochio, N., Nameki, N., Koshiba, S., Inoue, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-12-15 | | Release date: | 2006-06-15 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the plus-3 domain of human KIAA0252 protein
To be Published
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6TED | | STRUCTURE OF COMPLETE, ACTIVATED TRANSCRIPTION COMPLEX POL II-DSIF-PAF-SPT6 UNCOVERS ALLOSTERIC ELONGATION ACTIVATION BY RTF1 | | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit C, ... | | Authors: | Vos, S.M., Farnung, L., Cramer, P. | | Deposit date: | 2019-11-11 | | Release date: | 2020-07-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
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2BZE | | NMR STRUCTURE OF HUMAN RTF1 PLUS3 DOMAIN. | | Descriptor: | KIAA0252 PROTEIN | | Authors: | Truffault, V., Diercks, T., Ab, E., De Jong, R.N., Daniels, M.A., Kaptein, R., Folkers, G.E., Structural Proteomics in Europe (SPINE) | | Deposit date: | 2005-08-16 | | Release date: | 2007-01-03 | | Last modified: | 2020-01-15 | | Method: | SOLUTION NMR | | Cite: | Structure and DNA Binding of the Human Rtf1 Plus3 Domain.
Structure, 16, 2008
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4DM4 | | THE CONSERVED DOMAIN OF YEAST CDC73 | | Descriptor: | Cell division control protein 73 | | Authors: | Chen, H., Shi, N., Gao, Y., Li, X., Niu, L., Teng, M. | | Deposit date: | 2012-02-06 | | Release date: | 2012-08-22 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Crystallographic analysis of the conserved C-terminal domain of transcription factor Cdc73 from Saccharomyces cerevisiae reveals a GTPase-like fold.
Acta Crystallogr.,Sect.D, 68, 2012
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3OW8 | | CRYSTAL STRUCTURE OF THE WD REPEAT-CONTAINING PROTEIN 61 | | Descriptor: | WD repeat-containing protein 61, UNKNOWN ATOM OR ION | | Authors: | Tempel, W., Li, Z., Chao, X., Lam, R., Wernimont, A.K., He, H., Seitova, A., Pan, P.W., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC) | | Deposit date: | 2010-09-17 | | Release date: | 2010-09-29 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
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3U1U | | CRYSTAL STRUCTURE OF RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG PLUS-3 DOMAIN | | Descriptor: | RNA polymerase-associated protein RTF1 homolog, SULFATE ION, GLYCEROL, ... | | Authors: | Guo, Y., Tempel, W., Bian, C., Wernimont, A.K., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC) | | Deposit date: | 2011-09-30 | | Release date: | 2012-04-04 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of RNA polymerase-associated protein RTF1 homolog Plus-3 domain
to be published
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4B8C | | NUCLEASE MODULE OF THE YEAST CCR4-NOT COMPLEX | | Descriptor: | POLY(A) RIBONUCLEASE POP2, GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GLUCOSE-REPRESSIBLE ALCOHOL DEHYDROGENASE TRANSCRIPTIONAL EFFECTOR | | Authors: | Basquin, J., Conti, E. | | Deposit date: | 2012-08-26 | | Release date: | 2012-11-21 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
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5YDE | | CRYSTAL STRUCTURE OF A DISEASE-RELATED GENE, HCDC73(1-111) | | Descriptor: | Parafibromin | | Authors: | Sun, W., Kuang, X.L., Liu, Y.P., Tian, L.F., Yan, X.X., Xu, W.Q. | | Deposit date: | 2017-09-13 | | Release date: | 2017-12-20 | | Method: | X-RAY DIFFRACTION (1.023 Å) | | Cite: | Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
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5YDF | | CRYSTAL STRUCTURE OF A DISEASE-RELATED GENE, HCDC73(1-100) | | Descriptor: | Parafibromin | | Authors: | Sun, W., Kuang, X.L., Liu, Y.P., Tian, L.F., Yan, X.X., Xu, W.Q. | | Deposit date: | 2017-09-13 | | Release date: | 2017-12-20 | | Method: | X-RAY DIFFRACTION (1.399 Å) | | Cite: | Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
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