5ZYP
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STRUCTURE OF THE YEAST CTR9/PAF1 COMPLEX
Descriptor:RNA polymerase-associated protein CTR9,RNA polymerase II-associated protein 1, NICKEL (II) ION
Authors:Xie, Y., Zheng, M., Zhou, H., Long, J.
Deposit date:2018-05-28
Release date:2018-09-26
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
5ZYQ
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THE STRUCTURE OF HUMAN PAF1/CTR9 COMPLEX
Descriptor:RNA polymerase-associated protein CTR9 homolog,RNA polymerase II-associated factor 1 homolog
Authors:Xie, Y., Zheng, M., Zhou, H., Long, J.
Deposit date:2018-05-28
Release date:2018-09-26
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.531 Å)
Cite:Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
4M6T
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STRUCTURE OF HUMAN PAF1 AND LEO1 COMPLEX
Descriptor:RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ...
Authors:Shen, Y., Qin, X.
Deposit date:2013-08-11
Release date:2013-10-02
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structural insights into Paf1 complex assembly and histone binding
Nucleic Acids Res., 41, 2013
6AF0
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STRUCTURE OF CTR9, PAF1 AND CDC73 TERNARY COMPLEX FROM MYCELIOPHTHORA THERMOPHILA
Descriptor:Ctr9 protein, Paf1 protein, Cdc73 protein
Authors:Wang, Z., Deng, P., Zhou, Y.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3V46
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CRYSTAL STRUCTURE OF YEAST CDC73 C-TERMINAL DOMAIN
Descriptor:Cell division control protein 73
Authors:Amrich, C.G., VanDemark, A.P.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin.
J.Biol.Chem., 287, 2012
6GMH
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STRUCTURE OF ACTIVATED TRANSCRIPTION COMPLEX POL II-DSIF-PAF-SPT6
Descriptor:RPB1, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit C, ...
Authors:Vos, S.M., Farnung, L., Boehing, M., Linden, A., Wigge, C., Urlaub, H., Cramer, P.
Deposit date:2018-05-26
Release date:2018-08-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
4L1P
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CRYSTAL STRUCTURE OF HUMAN RTF1 PLUS3 DOMAIN
Descriptor:RNA polymerase-associated protein RTF1 homolog, GLYCEROL
Authors:Wier, A.D., Heroux, A., VanDemark, A.P.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L1U
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CRYSTAL STRUCTURE OF HUMAN RTF1 PLUS3 DOMAIN IN COMPLEX WITH SPT5 CTR PHOSPHOPEPTIDE
Descriptor:RNA polymerase-associated protein RTF1 homolog, Transcription elongation factor SPT5, SULFATE ION, ...
Authors:Wier, A.D., Heroux, A., VanDemark, A.P.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.424 Å)
Cite:Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
5E8B
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CRYSTAL STRUCTURE OF THE S. CEREVISIAE RTF1 HISTONE MODIFICATION DOMAIN MUTANT R126A
Descriptor:RNA polymerase-associated protein RTF1, SODIUM ION, BENZAMIDINE
Authors:Wier, A.D., Heroux, A., VanDemark, A.P.
Deposit date:2015-10-14
Release date:2016-11-09
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol. Cell, 64, 2016
5EMX
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CRYSTAL STRUCTURE OF THE S. CEREVISIAE RTF1 HISTONE MODIFICATION DOMAIN MUTANT R124A R126A R128A
Descriptor:RNA polymerase-associated protein RTF1
Authors:Wier, A.D., Heroux, A., VanDemark, A.P.
Deposit date:2015-11-06
Release date:2016-10-26
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol.Cell, 64, 2016
2DB9
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SOLUTION STRUCTURE OF THE PLUS-3 DOMAIN OF HUMAN KIAA0252 PROTEIN
Descriptor:Paf1/RNA polymerase II complex component
Authors:Yoneyama, M., Kigawa, T., Tochio, N., Nameki, N., Koshiba, S., Inoue, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-15
Release date:2006-06-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the plus-3 domain of human KIAA0252 protein
To be Published
6TED
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STRUCTURE OF COMPLETE, ACTIVATED TRANSCRIPTION COMPLEX POL II-DSIF-PAF-SPT6 UNCOVERS ALLOSTERIC ELONGATION ACTIVATION BY RTF1
Descriptor:DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit C, ...
Authors:Vos, S.M., Farnung, L., Cramer, P.
Deposit date:2019-11-11
Release date:2020-07-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
2BZE
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NMR STRUCTURE OF HUMAN RTF1 PLUS3 DOMAIN.
Descriptor:KIAA0252 PROTEIN
Authors:Truffault, V., Diercks, T., Ab, E., De Jong, R.N., Daniels, M.A., Kaptein, R., Folkers, G.E., Structural Proteomics in Europe (SPINE)
Deposit date:2005-08-16
Release date:2007-01-03
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Structure and DNA Binding of the Human Rtf1 Plus3 Domain.
Structure, 16, 2008
4DM4
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THE CONSERVED DOMAIN OF YEAST CDC73
Descriptor:Cell division control protein 73
Authors:Chen, H., Shi, N., Gao, Y., Li, X., Niu, L., Teng, M.
Deposit date:2012-02-06
Release date:2012-08-22
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystallographic analysis of the conserved C-terminal domain of transcription factor Cdc73 from Saccharomyces cerevisiae reveals a GTPase-like fold.
Acta Crystallogr.,Sect.D, 68, 2012
3OW8
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CRYSTAL STRUCTURE OF THE WD REPEAT-CONTAINING PROTEIN 61
Descriptor:WD repeat-containing protein 61, UNKNOWN ATOM OR ION
Authors:Tempel, W., Li, Z., Chao, X., Lam, R., Wernimont, A.K., He, H., Seitova, A., Pan, P.W., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-09-17
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
3U1U
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CRYSTAL STRUCTURE OF RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG PLUS-3 DOMAIN
Descriptor:RNA polymerase-associated protein RTF1 homolog, SULFATE ION, GLYCEROL, ...
Authors:Guo, Y., Tempel, W., Bian, C., Wernimont, A.K., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-09-30
Release date:2012-04-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of RNA polymerase-associated protein RTF1 homolog Plus-3 domain
to be published
4B8C
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NUCLEASE MODULE OF THE YEAST CCR4-NOT COMPLEX
Descriptor:POLY(A) RIBONUCLEASE POP2, GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GLUCOSE-REPRESSIBLE ALCOHOL DEHYDROGENASE TRANSCRIPTIONAL EFFECTOR
Authors:Basquin, J., Conti, E.
Deposit date:2012-08-26
Release date:2012-11-21
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
5YDE
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CRYSTAL STRUCTURE OF A DISEASE-RELATED GENE, HCDC73(1-111)
Descriptor:Parafibromin
Authors:Sun, W., Kuang, X.L., Liu, Y.P., Tian, L.F., Yan, X.X., Xu, W.Q.
Deposit date:2017-09-13
Release date:2017-12-20
Method:X-RAY DIFFRACTION (1.023 Å)
Cite:Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
5YDF
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CRYSTAL STRUCTURE OF A DISEASE-RELATED GENE, HCDC73(1-100)
Descriptor:Parafibromin
Authors:Sun, W., Kuang, X.L., Liu, Y.P., Tian, L.F., Yan, X.X., Xu, W.Q.
Deposit date:2017-09-13
Release date:2017-12-20
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
171916
PDB entries from 2020-12-02