8XQC

Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated PAF15 and hemimethylated DNA analog

This is a non-PDB format compatible entry.

Summary for 8XQC

• Entry DOI: 10.2210/pdb8xqc/pdb
• EMDB information: 38573
• Descriptor: DNA (cytosine-5)-methyltransferase 1, DNA (5'-D(*AP*CP*TP*TP*AP*(5CM)P*GP*GP*AP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*TP*CP*(C55)P*GP*TP*AP*AP*GP*T)-3'), ... (5 entities in total)
• Functional Keywords: dna methyltransferase, protein-dna complex, replication factor, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 151479.69

Authors

Kikuchi, A.,Hayashi, G.,Kori, S.,Arita, K. (deposition date: 2024-01-05, release date: 2025-01-15, Last modification date: 2025-06-25)

• Primary citation: Hayashi, G.,Takahashi, Y.,Kikuchi, A.,Kori, S.,Arita, K.,Murakami, H.; Activation of DNMT1 by Chemically Synthesized Dual monoubiquitinated PAF15 Protein; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.25 Å)