PDB: 661 resultsInfo pagesStatus searchChemie searchBIRD

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3SHU	Crystal structure of ZO-1 PDZ3 Descriptor: Tight junction protein ZO-1 Authors: Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M. Deposit date: 2011-06-17 Release date: 2011-09-28 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core To be Published
6X1N	Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ3 (mbDLG-3) Descriptor: GLYCEROL, mbDLG-3 protein Authors: Mackley, I, Amacher, J.F. Deposit date: 2020-05-19 Release date: 2020-11-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis. Protein Sci., 29, 2020
6LCB	Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 Descriptor: 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid, SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 Authors: Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. Deposit date: 2019-11-18 Release date: 2020-11-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 To Be Published
6XA8	Crystal Structure of Human Scribble PDZ1:Vangl2 complex Descriptor: 1,2-ETHANEDIOL, C-terminal peptide of Vangl2, PHOSPHATE ION, ... Authors: How, J.Y, Kvansakul, M. Deposit date: 2020-06-04 Release date: 2021-03-24 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis of the human Scribble-Vangl2 association in health and disease. Biochem.J., 478, 2021
6XA6	Crystal Structure of Human Scribble PDZ3:Vangl2 Complex Descriptor: 1,2-ETHANEDIOL, Protein scribble homolog, Vang-like protein 2 Authors: How, J.Y, Kvansakul, M. Deposit date: 2020-06-04 Release date: 2021-03-24 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural basis of the human Scribble-Vangl2 association in health and disease. Biochem.J., 478, 2021
6XA7	Crystal Structure of Human Scribble PDZ2:Vangl2 complex Descriptor: 1,2-ETHANEDIOL, Protein scribble homolog, Vang-like protein 2 Authors: How, J.Y, Kvansakul, M. Deposit date: 2020-06-04 Release date: 2021-03-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis of the human Scribble-Vangl2 association in health and disease. Biochem.J., 478, 2021
6KZ1	Complex structure of Whirlin and Myosin XVa Descriptor: Myosin XVa, Whirlin Authors: Lin, L, Wang, M, Shi, Y, Zhu, J, Zhang, R. Deposit date: 2019-09-22 Release date: 2020-09-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.694 Å) Cite: Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. Cell Rep, 34, 2021
6LCA	Crystal structure of human Dishevelled1 PDZ domain homotrimer Descriptor: SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 Authors: Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. Deposit date: 2019-11-18 Release date: 2020-11-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of human Dishevelled1 PDZ domain homotrimer To Be Published
6X20	PDZ domain from choanoflagellate GIPC (mbGIPC) bound to B1AR peptide Descriptor: mbGIPC protein Authors: Gao, M, Amacher, J.F. Deposit date: 2020-05-19 Release date: 2020-11-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.402 Å) Cite: Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis. Protein Sci., 29, 2020
3VQF	Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein Descriptor: E3 ubiquitin-protein ligase LNX Authors: Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H. Deposit date: 2012-03-22 Release date: 2013-03-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.199 Å) Cite: Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase To be Published
6JUE	The complex of PDZ and PBM Descriptor: Partitioning defective 3 homolog, SULFATE ION, THR-ILE-ILE-THR-LEU Authors: Liu, Z. Deposit date: 2019-04-13 Release date: 2020-04-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.549 Å) Cite: Par complex cluster formation mediated by phase separation. Nat Commun, 11, 2020
3SFJ	Crystal Structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36 inhibitor peptide Descriptor: Tax1-binding protein 3, decameric peptide iCAL36 Authors: Amacher, J.F, Madden, D.R. Deposit date: 2011-06-13 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.24 Å) Cite: A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR To be Published
6MTU	Crystal structure of human Scribble PDZ1:pMCC complex Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ... Authors: Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. Deposit date: 2018-10-22 Release date: 2019-08-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.141 Å) Cite: Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
3TSV	crystal structure of the third PDZ domain of the human ZO-1 MAGUK protein Descriptor: Tight junction protein ZO-1 Authors: Nomme, J, Lavie, A. Deposit date: 2011-09-13 Release date: 2011-10-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.989 Å) Cite: The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1. J.Biol.Chem., 286, 2011
6MTV	Crystal structure of human Scribble PDZ1:MCC complex Descriptor: Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, Protein scribble homolog, ... Authors: Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. Deposit date: 2018-10-22 Release date: 2019-08-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.597 Å) Cite: Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
3VQG	Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein Descriptor: C-terminal peptide from Immunoglobulin superfamily member 5, E3 ubiquitin-protein ligase LNX, SULFATE ION Authors: Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H. Deposit date: 2012-03-23 Release date: 2013-03-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase To be Published
6Y38	Crystal structure of Whirlin PDZ3 in complex with Myosin 15a C-terminal PDZ binding motif peptide Descriptor: Chains: C,D, Whirlin Authors: Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. Deposit date: 2020-02-17 Release date: 2020-10-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.697 Å) Cite: Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
6Y9Q	Crystal structure of Whirlin PDZ3_C-ter in complex with Taperin internal PDZ binding motif peptide Descriptor: Taperin, Whirlin Authors: Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. Deposit date: 2020-03-10 Release date: 2020-10-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.315 Å) Cite: Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
6Y9N	Crystal structure of Whirlin PDZ3_C-ter in complex with Myosin 15a C-terminal PDZ binding motif peptide Descriptor: Unconventional myosin-XV, Whirlin Authors: Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. Deposit date: 2020-03-10 Release date: 2020-10-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
6Y9O	Crystal structure of Whirlin PDZ3_C-ter in complex with CASK internal PDZ binding motif peptide Descriptor: Peripheral plasma membrane protein CASK, Whirlin Authors: Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. Deposit date: 2020-03-10 Release date: 2020-10-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.632 Å) Cite: Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
6ZBQ	Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling Descriptor: 5-fluoranyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... Authors: Roske, Y, Heinemann, U, Oschkinat, H. Deposit date: 2020-06-09 Release date: 2021-06-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
6ZBZ	Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling Descriptor: 1,2-ETHANEDIOL, 2-[(3,4-dimethylphenyl)sulfonylamino]-5-fluoranyl-benzoic acid, Dishevelled, ... Authors: Roske, Y, Heinemann, U, Oschkinat, H. Deposit date: 2020-06-09 Release date: 2021-06-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
6ZC7	Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling Descriptor: 5-bromanyl-2-[(phenylmethyl)sulfonylamino]benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... Authors: Roske, Y, Heinemann, U, Oschkinat, H. Deposit date: 2020-06-09 Release date: 2021-06-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
6ZC3	Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling Descriptor: 1,2-ETHANEDIOL, 5-fluoranyl-2-(methylsulfonylamino)benzoic acid, Dishevelled, ... Authors: Roske, Y, Heinemann, U, Oschkinat, H. Deposit date: 2020-06-09 Release date: 2021-06-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
6ZC6	Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling Descriptor: 1,2-ETHANEDIOL, 5-bromanyl-2-(naphthalen-2-ylsulfonylamino)benzoic acid, Segment polarity protein dishevelled homolog DVL-3 Authors: Roske, Y, Heinemann, U, Oschkinat, H. Deposit date: 2020-06-09 Release date: 2021-06-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021

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