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7N0T
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NMR structure of EpI[Y(SO)315Y]-OH
Descriptor: Alpha-conotoxin EpI
Authors:Conibear, A.C, Rosengren, K.J, Lee, H.S.
Deposit date:2021-05-26
Release date:2021-11-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Posttranslational modifications of alpha-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding.
Rsc Med Chem, 12, 2021
1M2C
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THREE-DIMENSIONAL STRUCTURE OF ALPHA-CONOTOXIN MII, NMR, 14 STRUCTURES
Descriptor: ALPHA-CONOTOXIN MII
Authors:Shon, K.J, Koerber, S.C, Rivier, J.E, Olivera, B.M, Mcintosh, J.M.
Deposit date:1997-09-15
Release date:1998-12-09
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors.
J.Biol.Chem., 271, 1996
1MTQ
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID BY NMR SPECTROSCOPY
Descriptor: alpha-conotoxin GID
Authors:Nicke, A, Loughnan, M.L, Millard, E.L, Alewood, P.F, Adams, D.J, Daly, N.L, Craik, D.J, Lewis, R.J.
Deposit date:2002-09-22
Release date:2003-02-11
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:Isolation, Structure, and Activity of GID, a Novel alpha 4/7-Conotoxin with an Extended N-terminal Sequence
J.BIOL.CHEM., 278, 2003
1MXN
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Solution structure of alpha-conotoxin AuIB
Descriptor: alpha-conotoxin AuIB
Authors:Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J.
Deposit date:2002-10-02
Release date:2002-12-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
2MG6
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Non-reducible analogues of alpha-conotoxin Vc1.1: [3,16]-trans dicarba Vc1.1
Descriptor: Alpha-conotoxin Vc1A
Authors:Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S.
Deposit date:2013-10-28
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2MFY
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Non-reducible analogues of alpha-conotoxin Vc1.1: [2,8]-trans dicarba Vc1.1
Descriptor: Alpha-conotoxin Vc1A
Authors:Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S.
Deposit date:2013-10-24
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2MFX
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Non-reducible analogues of alpha-conotoxin Vc1.1: [2,8]-cis dicarba Vc1.1
Descriptor: Alpha-conotoxin Vc1A
Authors:Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S.
Deposit date:2013-10-24
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2MDQ
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A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors
Descriptor: Alpha-conotoxin-like
Authors:Schroeder, C.I.
Deposit date:2013-09-16
Release date:2014-02-12
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:A novel alpha 4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha 3 beta 2 vs. alpha 6/ alpha 3 beta 2 beta 3 nicotinic acetylcholine receptors.
Faseb J., 28, 2014
2LZ5
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Solution structure of a Novel Alpha-Conotoxin TxIB
Descriptor: Conotoxin_TxIB
Authors:Luo, S, Zhangsun, D, Wu, Y, Zhu, X, Hu, Y, McIntyre, M, Christensen, S, Akcan, M, Craik, D, McIntosh, J.
Deposit date:2012-09-23
Release date:2012-12-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Characterization of a novel alpha-conotoxin from conus textile that selectively targets alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors.
J.Biol.Chem., 288, 2013
2MD6
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NMR SOLUTION STRUCTURE OF ALPHA CONOTOXIN LO1A FROM Conus longurionis
Descriptor: ALPHA CONOTOXIN LO1A
Authors:Maiti, M, Lescrinier, E, Herdewijn, P, Lebbe, E.K.M, Peigneur, S, D'Souza, L, Tytgat, J.
Deposit date:2013-09-01
Release date:2014-03-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-Function Elucidation of a New alpha-Conotoxin, Lo1a, from Conus longurionis.
J.Biol.Chem., 289, 2014
2M3I
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Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors
Descriptor: Alpha-conotoxin
Authors:Luo, S, Zhangsun, D, Zhu, X, Wu, Y, Hu, Y, Christensen, S, Akcan, M, Craik, D.J, McIntosh, J.M.
Deposit date:2013-01-20
Release date:2013-12-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Characterization of a Novel alpha-Conotoxin TxID from Conus textile That Potently Blocks Rat alpha 3 beta 4 Nicotinic Acetylcholine Receptors.
J.Med.Chem., 56, 2013
2NAY
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BU of 2nay by Molmil
The structure of the Bt1.8 peptide synthesized by solid-phase method
Descriptor: Conotoxin Bt1.8
Authors:Chenyun, G, Biling, H.
Deposit date:2016-01-14
Release date:2016-02-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure of the Bt1.8 peptide synthesized by solid-phase method
To be Published
2N07
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Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1
Descriptor: Alpha-conotoxin Vc1A
Authors:Yu, R, Seymour, V, Berecki, G, Jia, X, Akcan, M, Adams, D, Kaas, Q, Craik, D.
Deposit date:2015-03-04
Release date:2016-04-13
Method:SOLUTION NMR
Cite:Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1.
To be Published
1P1P
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BU of 1p1p by Molmil
[PRO7,13] AA-CONOTOXIN PIVA, NMR, 12 STRUCTURES
Descriptor: AA-CONOTOXIN PIVA
Authors:Han, K.-H, Hwang, K.-J, Kim, S.-M, Kim, S.-K, Gray, W.R, Olivera, B.M, Rivier, J, Shon, K.J.
Deposit date:1996-12-06
Release date:1997-07-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR structure determination of a novel conotoxin, [Pro 7,13] alpha A-conotoxin PIVA.
Biochemistry, 36, 1997
5XGL
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BU of 5xgl by Molmil
Co-crystal structure of Ac-AChBPP in complex with alpha-conotoxin LvIA
Descriptor: Alpha-conotoxin LvIA, Soluble acetylcholine receptor
Authors:Wang, X.Q, Xu, M.Y, Luo, S.L, Zhu, X.P.
Deposit date:2017-04-14
Release date:2018-06-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.439 Å)
Cite:The crystal structure of Ac-AChBP in complex with alpha-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
Protein Cell, 8, 2017
5JME
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BU of 5jme by Molmil
Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin PeIA
Descriptor: Soluble acetylcholine receptor, alpha-conotoxin PeIA from Conus pergrandis
Authors:Bobango, J, Sankaran, B, McIntosh, J.M, Talley, T.T.
Deposit date:2016-04-28
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.336 Å)
Cite:Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin PeIA
To Be Published
5CO5
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BU of 5co5 by Molmil
Crystal structure of Ac-AChBP in complex with conotoxin GIC
Descriptor: Alpha-conotoxin GIC, Soluble acetylcholine receptor
Authors:Wang, X.Q, Xu, M.Y, Luo, S.L, Lin, B.
Deposit date:2015-07-19
Release date:2016-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Ac-AChBP in complex with conotoxin GIC
To Be Published
6M4X
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Co-crystal structure of Ac-AChBPP in complex with [N9A]LvIA
Descriptor: Alpha-conotoxin LvIA, Soluble acetylcholine receptor
Authors:Wang, X.Q, Pan, S, Luo, S.L, Zhu, X.P.
Deposit date:2020-03-09
Release date:2021-03-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.998 Å)
Cite:The crystal structure of Ac-AChBP in complex with LvIA analogs reveals the mechanism of its selectivity towards different nAChR subtypes
To Be Published
6M4Z
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Co-crystal structure of Ac-AChBPP in complex with alpha-conotoxin [D11A]LvIA
Descriptor: Alpha-conotoxin LvIA, Soluble acetylcholine receptor
Authors:Wang, X.Q, Pan, S, Luo, S.L, Zhu, X.P.
Deposit date:2020-03-09
Release date:2021-03-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:The crystal structure of Ac-AChBP in complex with LvIA analogs reveals the mechanism of its selectivity towards different nAChR subtypes
To Be Published
7N43
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Alpha-conotoxin OmIA with unusual pharmacological properties at alpha7 nicotinic receptors
Descriptor: Acetylcholine-binding protein, Alpha-conotoxin OmIA
Authors:Ho, T.N.T, Abraham, N, Lewis, R.J.
Deposit date:2021-06-03
Release date:2021-12-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Unique Pharmacological Properties of alpha-Conotoxin OmIA at alpha 7 nAChRs.
Front Pharmacol, 12, 2021
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