Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1LGR
DownloadVisualize
BU of 1lgr by Molmil
INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE SYNTHETASE, MANGANESE (II) ION
Authors:Liaw, S.-H, Eisenberg, D.
Deposit date:1994-08-05
Release date:1994-11-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Interactions of nucleotides with fully unadenylylated glutamine synthetase from Salmonella typhimurium.
Biochemistry, 33, 1994
1F1H
DownloadVisualize
BU of 1f1h by Molmil
CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Gill, H.S, Eisenberg, D.
Deposit date:2000-05-19
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition.
Biochemistry, 40, 2001
1F52
DownloadVisualize
BU of 1f52 by Molmil
CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE SYNTHETASE, ...
Authors:Gill, H.S, Pfluegl, G.M.U, Eisenberg, D.
Deposit date:2000-06-12
Release date:2000-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition.
Biochemistry, 40, 2001
2D3B
DownloadVisualize
BU of 2d3b by Molmil
Crystal Structure of the Maize Glutamine Synthetase complexed with AMPPNP and Methionine sulfoximine
Descriptor: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M.
Deposit date:2005-09-26
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY
J.Biol.Chem., 281, 2006
2D3A
DownloadVisualize
BU of 2d3a by Molmil
Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Methionine sulfoximine Phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MANGANESE (II) ION, ...
Authors:Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M.
Deposit date:2005-09-26
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY
J.Biol.Chem., 281, 2006
2D3C
DownloadVisualize
BU of 2d3c by Molmil
Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Phosphinothricin Phosphate
Descriptor: (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M.
Deposit date:2005-09-26
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.81 Å)
Cite:Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY
J.Biol.Chem., 281, 2006
2BVC
DownloadVisualize
BU of 2bvc by Molmil
Crystal structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ...
Authors:Krajewski, W.W, Jones, T.A, Mowbray, S.L.
Deposit date:2005-06-23
Release date:2005-07-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Mycobacterium Tuberculosis Glutamine Synthetase in Complex with a Transition-State Mimic Provides Functional Insights.
Proc.Natl.Acad.Sci.USA, 102, 2005
4ACF
DownloadVisualize
BU of 4acf by Molmil
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH IMIDAZOPYRIDINE INHIBITOR ((4-(6-BROMO-3-(BUTYLAMINO)IMIDAZO(1,2-A)PYRIDIN-2-YL)PHENOXY) ACETIC ACID) AND L-METHIONINE-S-SULFOXIMINE PHOSPHATE.
Descriptor: CHLORIDE ION, GLUTAMINE SYNTHETASE 1, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Nilsson, M.T, Mowbray, S.L.
Deposit date:2011-12-15
Release date:2012-10-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis, Biological Evaluation and X-Ray Crystallographic Studies of Imidazo(1,2-A)Pyridine-Based Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors
Medchemcomm, 3, 2012
8PVG
DownloadVisualize
BU of 8pvg by Molmil
Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV
Descriptor: Glutamine synthetase
Authors:McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J.
Deposit date:2023-07-17
Release date:2023-11-29
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure determination by cryoEM at 100 keV.
Proc.Natl.Acad.Sci.USA, 120, 2023
3ZXR
DownloadVisualize
BU of 3zxr by Molmil
Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (3-(2-tert-butyl- 5-(pyridin-4-yl)-1H-imidazol-4-yl)quinoline) and L-methionine-S- sulfoximine phosphate.
Descriptor: 3-(2-TERT-BUTYL-5-(PYRIDIN-4-YL)-1H-IMIDAZOL-4-YL)QUINOLINE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ...
Authors:Nilsson, M.T, Mowbray, S.L.
Deposit date:2011-08-15
Release date:2012-04-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Trisubstituted Imidazoles as Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors.
J.Med.Chem., 55, 2012
3ZXV
DownloadVisualize
BU of 3zxv by Molmil
Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (4-(2-tert-butyl- 4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridin-2-amine) and L- methionine-S-sulfoximine phosphate
Descriptor: 4-(2-TERT-BUTYL-4-(6-METHOXYNAPHTHALEN-2-YL)-3H-IMIDAZOL-4-YL)PYRIDIN-2-AMINE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ...
Authors:Nilsson, M.T, Mowbray, S.L.
Deposit date:2011-08-16
Release date:2012-04-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Trisubstituted Imidazoles as Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors.
J.Med.Chem., 55, 2012
8OOX
DownloadVisualize
BU of 8oox by Molmil
Glutamine synthetase from Methermicoccus shengliensis at a resolution of 3.09 A
Descriptor: CITRIC ACID, GLYCEROL, Glutamine synthetase, ...
Authors:Mueller, M.-C, Lemaire, O.N, Wagner, T.
Deposit date:2023-04-06
Release date:2024-01-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations.
Commun Biol, 7, 2024
8OOW
DownloadVisualize
BU of 8oow by Molmil
Glutamine synthetase from Methermicoccus shengliensis at a resolution of 2.64 A
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Glutamine synthetase, ...
Authors:Mueller, M.-C, Lemaire, O.N, Wagner, T.
Deposit date:2023-04-06
Release date:2024-01-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations.
Commun Biol, 7, 2024
8OOZ
DownloadVisualize
BU of 8ooz by Molmil
Glutamine synthetase from Methermicoccus shengliensis in complex with MgATP at 2.7 A resolution
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, FORMIC ACID, GLYCEROL, ...
Authors:Mueller, M.-C, Lemaire, O.N, Wagner, T.
Deposit date:2023-04-06
Release date:2024-01-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations.
Commun Biol, 7, 2024
4BAX
DownloadVisualize
BU of 4bax by Molmil
Crystal structure of glutamine synthetase from Streptomyces coelicolor
Descriptor: GLUTAMINE SYNTHETASE, SODIUM ION
Authors:Zeth, K.
Deposit date:2012-09-16
Release date:2013-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of Glutamine Synthetase from Streptomyces Coelicolor
To be Published
4LNK
DownloadVisualize
BU of 4lnk by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-glutamate-AMPPCP complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Glutamine synthetase, ...
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
4LNF
DownloadVisualize
BU of 4lnf by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-Q
Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.949 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
7V4L
DownloadVisualize
BU of 7v4l by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State III
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4J
DownloadVisualize
BU of 7v4j by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State I
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4I
DownloadVisualize
BU of 7v4i by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb decamer assembly
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4K
DownloadVisualize
BU of 7v4k by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State II
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
4LNN
DownloadVisualize
BU of 4lnn by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of apo form of GS
Descriptor: Glutamine synthetase, MAGNESIUM ION, SULFATE ION
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
4LNI
DownloadVisualize
BU of 4lni by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5793 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
4LNO
DownloadVisualize
BU of 4lno by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: form two of GS-1
Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
8TFK
DownloadVisualize
BU of 8tfk by Molmil
Cryo-EM structure of the Methanosarcina mazei glutamine synthetase (GS) with Met-Sox-P and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A.
Deposit date:2023-07-11
Release date:2023-11-15
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon