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7TDV
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BU of 7tdv by Molmil
Crystal structure of S. aureus glutamine synthetase in Met-Sox-P/ADP transition state complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A.
Deposit date:2022-01-03
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TDP
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BU of 7tdp by Molmil
Structure of Paenibacillus polymyxa GS bound to Met-Sox-P-ADP (Transition state complex) to 1.98 Angstom
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A.
Deposit date:2022-01-02
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7W85
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BU of 7w85 by Molmil
Structural of the filamentous Escherichia coli glutamine synthetase
Descriptor: Glutamine synthetase, NICKEL (II) ION
Authors:Huang, P.-C, Chen, S.-K, Wu, K.-P.
Deposit date:2021-12-07
Release date:2022-04-06
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural basis for the helical filament formation of Escherichia coli glutamine synthetase.
Protein Sci., 31, 2022
7V4J
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BU of 7v4j by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State I
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4I
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BU of 7v4i by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb decamer assembly
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4H
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BU of 7v4h by Molmil
Cryo-EM Structure of Glycine max glutamine synthetase GmGS Beta2
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4K
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BU of 7v4k by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State II
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Method:ELECTRON MICROSCOPY
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4L
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BU of 7v4l by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State III
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7EVT
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BU of 7evt by Molmil
Crystal structure of the N-terminal degron-truncated human glutamine synthetase
Descriptor: Glutamine synthetase
Authors:Chek, M.F, Kim, S.Y, Mori, T, Hakoshima, T.
Deposit date:2021-05-22
Release date:2021-11-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of N-terminal degron-truncated human glutamine synthetase.
Acta Crystallogr.,Sect.F, 77, 2021
7CQQ
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BU of 7cqq by Molmil
GmaS in complex with AMPPNP and MetSox
Descriptor: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Li, C.Y, Zhang, Y.Z.
Deposit date:2020-08-11
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQL
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BU of 7cql by Molmil
Apo GmaS without ligand
Descriptor: Type III glutamate--ammonia ligase
Authors:Li, C.Y, Zhang, Y.Z.
Deposit date:2020-08-11
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQN
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BU of 7cqn by Molmil
GmaS in complex with AMPPCP
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Type III glutamate--ammonia ligase
Authors:Li, C.Y, Zhang, Y.Z.
Deposit date:2020-08-11
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.962 Å)
Cite:Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQU
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BU of 7cqu by Molmil
GmaS/ADP/MetSox-P complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MAGNESIUM ION, ...
Authors:Li, C.Y, Zhang, Y.Z.
Deposit date:2020-08-11
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQX
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BU of 7cqx by Molmil
GmaS/ADP complex-Conformation 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase
Authors:Li, C.Y, Zhang, Y.Z.
Deposit date:2020-08-11
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQW
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BU of 7cqw by Molmil
GmaS/ADP complex-Conformation 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase
Authors:Li, C.Y, Zhang, Y.Z.
Deposit date:2020-08-11
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CPR
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BU of 7cpr by Molmil
glutamine synthetase from Drosophila
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase 2 cytoplasmic
Authors:Yin, H.S, Chen, W.T.
Deposit date:2020-08-07
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural Insight into the Contributions of the N-Terminus and Key Active-Site Residues to the Catalytic Efficiency of Glutamine Synthetase 2.
Biomolecules, 10, 2020
6PEW
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BU of 6pew by Molmil
CryoEM Plasmodium falciparum glutamine synthetase
Descriptor: Glutamine synthetase
Authors:Ho, C.M, Lai, M, Zhou, Z.H.
Deposit date:2019-06-21
Release date:2019-12-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu.
Nat.Methods, 17, 2020
5ZLP
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BU of 5zlp by Molmil
Crystal structure of glutamine synthetase from helicobacter pylori
Descriptor: (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Joo, H.K, Lee, J.Y.
Deposit date:2018-03-29
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Sci Rep, 8, 2018
5ZLI
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BU of 5zli by Molmil
Crystal structure of glutamine synthetase from helicobacter pylori
Descriptor: Glutamine synthetase
Authors:Joo, H.K, Lee, J.Y.
Deposit date:2018-03-28
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Sci Rep, 8, 2018
5LDF
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BU of 5ldf by Molmil
Maltose binding protein genetically fused to dodecameric glutamine synthetase
Descriptor: Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Coscia, F, Petosa, C, Schoehn, G.
Deposit date:2016-06-25
Release date:2016-08-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein.
Sci Rep, 6, 2016
5DM3
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BU of 5dm3 by Molmil
Crystal Structure of Glutamine Synthetase from Chromohalobacter salexigens DSM 3043(Csal_0679, TARGET EFI-550015) with bound ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, L-glutamine synthetase
Authors:Yadava, U, Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2015-09-07
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Glutamine Synthetase from Chromohalobacter salexigens DSM 3043(Csal_0679, TARGET EFI-550015) with bound ADP
To be published
4XYC
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BU of 4xyc by Molmil
NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES
Descriptor: 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, Glutamine synthetase 1
Authors:Couturier, C, Silve, S, Morales, R, Ppessegue, B, Llopart, S, Nair, A, Bauer, A, Scheiper, B, poeverlein, c, Ganzhorn, A, Lagrange, S, Bacque, E.
Deposit date:2015-02-02
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies.
Bioorg.Med.Chem.Lett., 25, 2015
4S17
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BU of 4s17 by Molmil
The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
Descriptor: ACETATE ION, Glutamine synthetase, MAGNESIUM ION
Authors:Cuff, M, Tan, K, Mack, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2015-01-08
Release date:2015-01-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
To be Published
4S0R
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BU of 4s0r by Molmil
Structure of GS-TnrA complex
Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
Authors:Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K.
Deposit date:2015-01-04
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
4LNK
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BU of 4lnk by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-glutamate-AMPPCP complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Glutamine synthetase, ...
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013

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