3SVK
 
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6PCA
 | | Crystal structure of beta-ketoadipyl-CoA thiolase | | Descriptor: | ACETATE ION, Beta-ketoadipyl-CoA thiolase, CHLORIDE ION, ... | | Authors: | Sukritee, B, Panjikar, S. | | Deposit date: | 2019-06-17 | | Release date: | 2020-05-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase.
J Struct Biol X, 4, 2020
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6PCB
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1DLU
 | | UNLIGANDED BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BIOSYNTHETIC THIOLASE, SULFATE ION | | Authors: | Modis, Y, Wierenga, R.K. | | Deposit date: | 1999-12-12 | | Release date: | 2000-04-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase.
J.Mol.Biol., 297, 2000
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1DM3
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6PCC
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7XLY
 | | Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis | | Descriptor: | Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION | | Authors: | Singh, R, Kundu, P, Singh, B.K, Bhattacharyya, S, Das, A.K. | | Deposit date: | 2022-04-23 | | Release date: | 2023-04-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties.
Febs J., 290, 2023
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6BJB
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1DLV
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6BN2
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6HSJ
 | | Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA | | Descriptor: | ACETATE ION, COENZYME A, GLYCEROL, ... | | Authors: | Wierenga, R.K, Kiema, T.R, Thapa, C.J. | | Deposit date: | 2018-10-01 | | Release date: | 2019-01-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
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7VTR
 | | 3-ketoacyl-CoA thiolase Tfu_0875 | | Descriptor: | Thiolase | | Authors: | Liu, L.X, Zhou, S.H, Deng, Y. | | Deposit date: | 2021-10-30 | | Release date: | 2022-11-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Rational Design of the Substrate Tunnel of beta-Ketothiolase Reveals a Local Cationic Domain Modulated Rule that Improves the Efficiency of Claisen Condensation
Acs Catalysis, 13, 2023
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6HRV
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6DV2
 | | Crystal Structure of Human Mitochondrial Trifunctional Protein | | Descriptor: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | | Authors: | Fu, Z, Xia, C, Battaile, K.P, Kim, J.P. | | Deposit date: | 2018-06-22 | | Release date: | 2018-09-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Crystal structure of human mitochondrial trifunctional protein, a fatty acid beta-oxidation metabolon.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6HSP
 | | Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA and octanoyl-CoA | | Descriptor: | COENZYME A, GLYCEROL, OCTANOYL-COENZYME A, ... | | Authors: | Wierenga, R.K, Kiema, T.R, Thapa, C.J. | | Deposit date: | 2018-10-01 | | Release date: | 2019-01-02 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
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7YXM
 | | Benzoylsuccinyl-CoA thiolase with coenzyme A | | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Benzoylsuccinyl-CoA thiolase subunit, ... | | Authors: | Ermler, U, Heider, J, Weidenweber, S. | | Deposit date: | 2022-02-16 | | Release date: | 2022-04-06 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism.
Febs J., 289, 2022
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4W61
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7YVY
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4WYS
 | | Crystal structure of thiolase from Escherichia coli | | Descriptor: | Acetyl-CoA acetyltransferase | | Authors: | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | | Deposit date: | 2014-11-18 | | Release date: | 2015-10-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
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4O9C
 | | Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16 | | Descriptor: | Acetyl-CoA acetyltransferase, COENZYME A | | Authors: | Kim, E.J, Kim, J, Kim, S, Kim, K.J. | | Deposit date: | 2014-01-02 | | Release date: | 2014-12-17 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
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4WYR
 | | Crystal structure of thiolase mutation (V77Q,N153Y,A286K) from Clostridium acetobutylicum | | Descriptor: | Acetyl-CoA acetyltransferase, DI(HYDROXYETHYL)ETHER, GLYCEROL | | Authors: | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | | Deposit date: | 2014-11-18 | | Release date: | 2015-10-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
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4XL4
 | | Crystal structure of thiolase from Clostridium acetobutylicum in complex with CoA | | Descriptor: | Acetyl-CoA acetyltransferase, COENZYME A, GLYCEROL | | Authors: | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | | Deposit date: | 2015-01-13 | | Release date: | 2015-10-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
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2C7Z
 | | Plant enzyme crystal form II | | Descriptor: | 3-KETOACYL-COA THIOLASE 2 | | Authors: | Sundaramoorthy, R, Micossi, E, Alphey, M.S, Leonard, G.A, Hunter, W.N. | | Deposit date: | 2005-11-30 | | Release date: | 2006-05-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | The Crystal Structure of a Plant 3-Ketoacyl-Coa Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid Beta-Oxidation.
J.Mol.Biol., 359, 2006
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2C7Y
 | | plant enzyme | | Descriptor: | 3-KETOACYL-COA THIOLASE 2 | | Authors: | Sundaramoorthy, R, Micossi, E, Alphey, M.S, Germain, V, Bryce, J.H, Smith, S.M, Leonard, G.A, Hunter, W.N. | | Deposit date: | 2005-11-30 | | Release date: | 2006-05-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Crystal Structure of a Plant 3-Ketoacyl-Coa Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid Beta-Oxidation.
J.Mol.Biol., 359, 2006
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5LOT
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