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5A9W
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BU of 5a9w by Molmil
Structure of GDPCP BipA
Descriptor: GTP-BINDING PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.
Deposit date:2015-07-23
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
2D74
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BU of 2d74 by Molmil
Crystal structure of translation initiation factor aIF2betagamma heterodimer
Descriptor: Translation initiation factor 2 beta subunit, Translation initiation factor 2 gamma subunit, ZINC ION
Authors:Sokabe, M, Yao, M, Sakai, N, Toya, S, Tanaka, I.
Deposit date:2005-11-16
Release date:2006-07-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.
Proc.Natl.Acad.Sci.USA, 103, 2006
5H7K
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BU of 5h7k by Molmil
Crystal structure of Elongation factor 2 GDP-form
Descriptor: Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
Authors:Tanzawa, T, Kato, K, Uchiumi, T, Yao, M.
Deposit date:2016-11-18
Release date:2018-02-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
5HXB
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BU of 5hxb by Molmil
Cereblon in complex with DDB1, CC-885, and GSPT1
Descriptor: 1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ...
Authors:Chamberlain, P.P, Matyskiela, M, Pagarigan, B.
Deposit date:2016-01-30
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Nature, 535, 2016
5IMR
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BU of 5imr by Molmil
Structure of ribosome bound to cofactor at 5.7 angstrom resolution
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G.
Deposit date:2016-03-06
Release date:2016-05-18
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome
J.Biol.Chem., 291, 2016
5HAU
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BU of 5hau by Molmil
Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
Deposit date:2015-12-30
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
5IMQ
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BU of 5imq by Molmil
Structure of ribosome bound to cofactor at 3.8 angstrom resolution
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G.
Deposit date:2016-03-06
Release date:2016-05-18
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome
J.Biol.Chem., 291, 2016
5I4R
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BU of 5i4r by Molmil
Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified)
Descriptor: Contact-dependent inhibitor A, Contact-dependent inhibitor I, Elongation factor Tu, ...
Authors:Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2016-02-12
Release date:2017-06-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
5H7L
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BU of 5h7l by Molmil
Complex of Elongation factor 2-50S ribosomal protein L12
Descriptor: 50S ribosomal protein L12, Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Tanzawa, T, Kato, K, Uchiumi, T, Yao, M.
Deposit date:2016-11-18
Release date:2018-02-21
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
5H7J
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BU of 5h7j by Molmil
Crystal structure of Elongation factor 2
Descriptor: Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Tanzawa, T, Kato, K, Uchiumi, T, Yao, M.
Deposit date:2016-11-18
Release date:2018-02-21
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
5IZL
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BU of 5izl by Molmil
The crystal structure of human eEFSec in complex with GDPCP
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Selenocysteine-specific elongation factor
Authors:Dobosz-Bartoszek, M, Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5I4Q
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BU of 5i4q by Molmil
Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3)
Descriptor: CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ...
Authors:Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2016-02-12
Release date:2017-06-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
5IZM
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BU of 5izm by Molmil
The crystal structure of human eEFSec in complex with GDPNP
Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Selenocysteine-specific elongation factor
Authors:Dobosz-Bartoszek, M, Otwinowski, Z, Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5J8B
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BU of 5j8b by Molmil
Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Lin, J, Steitz, T.A.
Deposit date:2016-04-07
Release date:2016-05-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Elongation factor 4 remodels the A-site tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IZK
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BU of 5izk by Molmil
The crystal structure of human eEFSec in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Selenocysteine-specific elongation factor
Authors:Dobosz-Bartoszek, M, Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
6FEC
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BU of 6fec by Molmil
Human cap-dependent 48S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schaffitzel, C, Schaffitzel, C.
Deposit date:2017-12-31
Release date:2018-03-14
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structure of a human cap-dependent 48S translation pre-initiation complex.
Nucleic Acids Res., 46, 2018
3WXM
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BU of 3wxm by Molmil
Crystal structure of archaeal Pelota and GTP-bound EF1 alpha complex
Descriptor: Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kobayashi, K, Ishitani, R, Nureki, O.
Deposit date:2014-08-04
Release date:2014-09-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1 alpha complex
Proc.Natl.Acad.Sci.USA, 107, 2010
8EWH
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BU of 8ewh by Molmil
Salmonella typhimurium GTPase BIPA
Descriptor: 50S ribosomal subunit assembly factor BipA, SODIUM ION
Authors:Brown, R.S, deLivron, M.A, Robinson, V.L.
Deposit date:2022-10-23
Release date:2022-11-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystallographic and Biochemical Characterization of the GTPase and Ribosome Binding Properties of Salmonella typhimuirum BipA
J Biomol Struct Dyn., 24:6, 2007
6FYY
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BU of 6fyy by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
3WYA
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BU of 3wya by Molmil
Crystal structure of GDP-bound EF1alpha from Pyrococcus horikoshii
Descriptor: Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE
Authors:Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T.
Deposit date:2014-08-22
Release date:2014-12-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha.
Nucleic Acids Res., 42, 2014
4ACA
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BU of 4aca by Molmil
CRYSTAL STRUCTURE OF TRANSLATION ELONGATION FACTOR SELB FROM METHANOCOCCUS MARIPALUDIS, APO FORM
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Leibundgut, M, Frick, C, Thanbichler, M, Boeck, A, Ban, N.
Deposit date:2011-12-14
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Selenocysteine tRNA-Specific Elongation Factor Selb is a Structural Chimaera of Elongation and Initiation Factors.
Embo J., 24, 2005
6GSN
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BU of 6gsn by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA (1798-MER), 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6GXP
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BU of 6gxp by Molmil
Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP(RF3-only)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GQ1
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BU of 6gq1 by Molmil
Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y.
Deposit date:2018-06-07
Release date:2018-07-11
Last modified:2018-08-08
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
4ACB
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BU of 4acb by Molmil
CRYSTAL STRUCTURE OF TRANSLATION ELONGATION FACTOR SELB FROM METHANOCOCCUS MARIPALUDIS IN COMPLEX WITH THE GTP ANALOGUE GPPNHP
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Leibundgut, M, Frick, C, Thanbichler, M, Boeck, A, Ban, N.
Deposit date:2011-12-14
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Selenocysteine tRNA-Specific Elongation Factor Selb is a Structural Chimaera of Elongation and Initiation Factors.
Embo J., 24, 2005

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PDB entries from 2024-09-18

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