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3RYR
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BU of 3ryr by Molmil
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator
Authors:Knapp, J, White, M.A, Lee, J.C.
Deposit date:2011-05-11
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Domain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp)
To be Published
1O3Q
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BU of 1o3q by Molmil
PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor: 5'-D(*AP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
1O3R
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BU of 1o3r by Molmil
PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor: 5'-D(*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
1O7F
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BU of 1o7f by Molmil
CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF EPAC2
Descriptor: CAMP-DEPENDENT RAP1 GUANINE-NUCLEOTIDE EXCHANGE FACTOR
Authors:Rehmann, H, Prakash, B, Wolf, E, Rueppel, A, De Rooij, J, Bos, J.L, Wittinghofer, A.
Deposit date:2002-11-04
Release date:2002-11-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Regulation of the Camp-Binding Domains of Epac2
Nat.Struct.Biol., 10, 2002
7PZB
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BU of 7pzb by Molmil
Structure of the Clr-cAMP-DNA complex
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*GP*TP*AP*AP*CP*AP*TP*TP*AP*CP*TP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*TP*AP*AP*TP*GP*TP*TP*AP*C)-3'), ...
Authors:Werel, L, Essen, L.-O.
Deposit date:2021-10-11
Release date:2022-11-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structural Basis of Dual Specificity of Sinorhizobium meliloti Clr, a cAMP and cGMP Receptor Protein.
Mbio, 14, 2023
7PZA
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BU of 7pza by Molmil
Structure of the Clr-cAMP-DNA complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*GP*TP*AP*AP*CP*AP*TP*TP*AP*CP*TP*CP*GP)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*TP*AP*AP*TP*GP*TP*TP*AP*C)-3'), ...
Authors:Werel, L, Essen, L.-O.
Deposit date:2021-10-11
Release date:2022-11-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural Basis of Dual Specificity of Sinorhizobium meliloti Clr, a cAMP and cGMP Receptor Protein.
Mbio, 14, 2023
1O5L
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BU of 1o5l by Molmil
Crystal structure of Transcriptional regulator (TM1171) from Thermotoga maritima at 2.30 A resolution
Descriptor: transcriptional regulator, crp family
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2003-09-23
Release date:2003-10-07
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171.
Protein Sci., 13, 2004
1O3T
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BU of 1o3t by Molmil
PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor: 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
7RH9
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BU of 7rh9 by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in apo state
Descriptor: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-16
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHH
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BU of 7rhh by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cGMP-bound openI state
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHG
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BU of 7rhg by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cAMP-bound state
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHJ
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BU of 7rhj by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-blocked open state
Descriptor: (2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, ...
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHL
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BU of 7rhl by Molmil
Cryo-EM structure of human rod Apo CNGA1/B1 channel with CLZ coiled coil
Descriptor: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHI
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BU of 7rhi by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cGMP-bound openII state
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHK
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BU of 7rhk by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-trapped closed state
Descriptor: (2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, ...
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7W5Z
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BU of 7w5z by Molmil
Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ...
Authors:Zhou, L, Maldonado, M, Padavannil, A, Letts, J.
Deposit date:2021-11-30
Release date:2022-04-06
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
7RHS
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BU of 7rhs by Molmil
Cryo-EM structure of apo-state of human CNGA3/CNGB3 channel
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cyclic nucleotide-gated cation channel alpha-3, Cyclic nucleotide-gated cation channel beta-3, ...
Authors:Zheng, X, Yang, J.
Deposit date:2021-07-18
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structure of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 29, 2022
7RSH
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BU of 7rsh by Molmil
SthK Y26F Closed State
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK
Authors:Gao, X, Nimigean, C.
Deposit date:2021-08-11
Release date:2022-11-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
1O3S
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BU of 1o3s by Molmil
PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor: 5'-D(*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Chen, S, Ebright, R.H, Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: Alteration of DNA Binding Specificity Through Alteration of DNA Kinking
J.Mol.Biol., 314, 2001
7YID
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BU of 7yid by Molmil
Human KCNH5 closed state 1
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIH
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BU of 7yih by Molmil
Human KCNH5 open state
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIF
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BU of 7yif by Molmil
Human KCNH5 pre-open state 1
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIJ
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BU of 7yij by Molmil
Human KCNH5 pore dilation but the non-conducting state
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIG
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BU of 7yig by Molmil
Human KCNH5 pre-open state 2
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIE
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BU of 7yie by Molmil
Human KCNH5-closed state 2
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023

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