6VVQ
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3P0L
| Human steroidogenic acute regulatory protein | Descriptor: | Steroidogenic acute regulatory protein, mitochondrial | Authors: | Lehtio, L, Siponen, M, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-09-29 | Release date: | 2010-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
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2R55
| Human StAR-related lipid transfer protein 5 | Descriptor: | StAR-related lipid transfer protein 5 | Authors: | Lehtio, L, Busam, R.D, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Herman, M.D, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Sagemark, J, Sundstrom, M, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Persson, C, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-03 | Release date: | 2007-09-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
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5I9J
| Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A | Descriptor: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, SULFATE ION, ... | Authors: | Horvath, M.P, Bernstein, P.S, Li, B, George, E.W, Tran, Q.T. | Deposit date: | 2016-02-20 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure of the lutein-binding domain of human StARD3 at 1.74 angstrom resolution and model of a complex with lutein. Acta Crystallogr.,Sect.F, 72, 2016
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7U9D
| Crystal Structure of Human Phosphatidylcholine Transfer Protein in Complex with PC(16:0/20:4) | Descriptor: | GLYCEROL, Phosphatidylcholine transfer protein, [(2~{R})-1-hexadecanoyloxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propan-2-yl] (5~{Z},8~{Z},11~{Z},14~{Z})-icosa-5,8,11,14-tetraenoate | Authors: | Druzak, S.A. | Deposit date: | 2022-03-10 | Release date: | 2023-04-12 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Ligand dependent interaction between PC-TP and PPAR delta mitigates diet-induced hepatic steatosis in male mice. Nat Commun, 14, 2023
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6SER
| Crystal structure of human STARD10 | Descriptor: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, START domain-containing protein 10, ... | Authors: | Cheng, K, Wigley, D.B. | Deposit date: | 2019-07-30 | Release date: | 2020-08-26 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | The crystal structure of human STARD10 To Be Published
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5BRL
| Crystal Structure of L124D STARD4 | Descriptor: | StAR-related lipid transfer protein 4 | Authors: | Iaea, D.B, Dikiy, I, Kiburu, I, Eliezer, D.E, Maxfield, F.R. | Deposit date: | 2015-05-31 | Release date: | 2015-07-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | STARD4 Membrane Interactions and Sterol Binding. Biochemistry, 54, 2015
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3FO5
| Human START domain of Acyl-coenzyme A thioesterase 11 (ACOT11) | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, CHLORIDE ION, GLYCEROL, ... | Authors: | Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van-Den-Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Shueler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-12-27 | Release date: | 2009-02-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
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1EM2
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2Z9Z
| Crystal structure of CERT START domain(N504A mutant), in complex with C10-diacylglycerol | Descriptor: | (2S)-3-hydroxypropane-1,2-diyl didecanoate, Lipid-transfer protein CERT | Authors: | Kudo, N, Kumagai, K, Wakatsuki, S, Nishijima, M, Hanada, K, Kato, R. | Deposit date: | 2007-09-26 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide. Proc.Natl.Acad.Sci.Usa, 105, 2008
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6IEZ
| Crystal structure of CERT START domain in complex with compound B16 | Descriptor: | 2-({4'-pentyl-3'-[2-(pyridin-2-yl)ethyl][1,1'-biphenyl]-4-yl}sulfonyl)ethan-1-ol, LIPID-TRANSFER PROTEIN CERT | Authors: | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | Deposit date: | 2018-09-18 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
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6IF0
| Crystal structure of CERT START domain in complex with compound D16 | Descriptor: | 2-({4'-pentyl-3'-[(Z)-2-(pyridin-2-yl)ethenyl][1,1'-biphenyl]-4-yl}sulfonyl)ethan-1-ol, LIPID-TRANSFER PROTEIN CERT | Authors: | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | Deposit date: | 2018-09-18 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
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2MOU
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2Z9Y
| Crystal structure of CERT START domain in complex with C10-diacylglycerol | Descriptor: | (2S)-3-hydroxypropane-1,2-diyl didecanoate, Lipid-transfer protein CERT | Authors: | Kudo, N, Kumagai, K, Wakatsuki, S, Nishijima, M, Hanada, K, Kato, R. | Deposit date: | 2007-09-26 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2PSO
| Human StarD13 (DLC2) lipid transfer and protein localization domain | Descriptor: | StAR-related lipid transfer protein 13 | Authors: | Lehtio, L, Busam, R, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Ogg, D, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van den Berg, S, Weigelt, J, Welin, M, Persson, C, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-07 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
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6J81
| Crystal structure of CERT START domain in complex with compound E14 | Descriptor: | 2-[4-[4-propyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT | Authors: | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | Deposit date: | 2019-01-18 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
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6J0O
| Crystal structure of CERT START domain in complex with compound SC1 | Descriptor: | 2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT, UNKNOWN ATOM OR ION | Authors: | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | Deposit date: | 2018-12-25 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
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3H3T
| Crystal structure of the CERT START domain in complex with HPA-16 | Descriptor: | Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]hexadecanamide | Authors: | Kudo, N, Wakatsuki, S, Kato, R. | Deposit date: | 2009-04-17 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
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3H3R
| Crystal structure of the CERT START domain in complex with HPA-14 | Descriptor: | Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]tetradecanamide | Authors: | Kudo, N, Wakatsuki, S, Kato, R. | Deposit date: | 2009-04-17 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
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1JSS
| Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4). | Descriptor: | cholesterol-regulated START protein 4 | Authors: | Romanowski, M.J, Soccio, R.E, Breslow, J.L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2001-08-17 | Release date: | 2002-04-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain. Proc.Natl.Acad.Sci.USA, 99, 2002
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6L1D
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6L1M
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3H3S
| Crystal structure of the CERT START domain in complex with HPA-15 | Descriptor: | Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]pentadecanamide | Authors: | Kudo, N, Wakatsuki, S, Kato, R. | Deposit date: | 2009-04-17 | Release date: | 2010-03-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
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1LN3
| Structure of Human Phosphatidylcholine Transfer Protein in Complex with Palmitoyl-Linoleoyl Phosphatidylcholine (Seleno-Met Protein) | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Phosphatidylcholine transfer protein | Authors: | Roderick, S.L, Chan, W.W, Agate, D.S, Olsen, L.R, Vetting, M.W, Rajashankar, K.R, Cohen, D.E. | Deposit date: | 2002-05-02 | Release date: | 2002-06-26 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of human phosphatidylcholine transfer protein in complex with its ligand. Nat.Struct.Biol., 9, 2002
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3H3Q
| Crystal structure of the CERT START domain in complex with HPA-13 | Descriptor: | Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]tridecanamide | Authors: | Kudo, N, Wakatsuki, S, Kato, R. | Deposit date: | 2009-04-17 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
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