6VVQ

Human START domain of Acyl-coenzyme A thioesterase 11 (ACOT11) bound to Myristic Acid

Summary for 6VVQ

Entry DOI	10.2210/pdb6vvq/pdb
Descriptor	Acyl-coenzyme A thioesterase 11, MYRISTIC ACID (3 entities in total)
Functional Keywords	start, lipid, thioesterase, allostery, lipid binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	118902.26
Authors	Tillman, M.C.,Ortlund, E.A. (deposition date: 2020-02-18, release date: 2020-09-02, Last modification date: 2023-10-11)
Primary citation	Tillman, M.C.,Imai, N.,Li, Y.,Khadka, M.,Okafor, C.D.,Juneja, P.,Adhiyaman, A.,Hagen, S.J.,Cohen, D.E.,Ortlund, E.A. Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine. Proc.Natl.Acad.Sci.USA, 117:22080-22089, 2020 Cited by PubMed: 32820071 DOI: 10.1073/pnas.2003877117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.09 Å)

Structure validation