Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4D8S
DownloadVisualize
BU of 4d8s by Molmil
Influenza NA in complex with antiviral compound
Descriptor: CALCIUM ION, Neuraminidase, pentan-3-yl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid
Authors:Kerry, P.S, Russell, R.J.M.R.
Deposit date:2012-01-11
Release date:2013-02-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Exploring the interactions of unsaturated glucuronides with influenza virus sialidase.
J.Med.Chem., 55, 2012
7S0I
DownloadVisualize
BU of 7s0i by Molmil
CRYSTAL STRUCTURE OF N1 NEURAMINIDASE FROM A/Michigan/45/2015(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2021-08-30
Release date:2021-12-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.892 Å)
Cite:A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model.
Mbio, 12, 2021
4M3M
DownloadVisualize
BU of 4m3m by Molmil
Influenza Neuraminidase in complex with a stereomutated analogue of Oseltamivir carboxylate
Descriptor: (3R,4S,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Kerry, P.S.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylate.
Org.Biomol.Chem., 12, 2014
7NN9
DownloadVisualize
BU of 7nn9 by Molmil
NATIVE INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE N9, ...
Authors:Varghese, J.N, Colman, P.M.
Deposit date:1995-03-15
Release date:1996-04-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase.
Protein Sci., 4, 1995
8DWB
DownloadVisualize
BU of 8dwb by Molmil
Neuraminidase from influenza virus A/Moscow/10/1999(H3N2) in complex with sialic acid
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, N-acetyl-alpha-neuraminic acid, ...
Authors:Lei, R, Hernandez Garcia, A.
Deposit date:2022-08-01
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Mutational fitness landscape of human influenza H3N2 neuraminidase.
Cell Rep, 42, 2023
9EWQ
DownloadVisualize
BU of 9ewq by Molmil
Influenza virus neuraminidase N1 NC13 ectodomain with a tetrabrachio-domain stalk
Descriptor: Neuraminidase
Authors:Roelofs, M.C, Zeev-Ben-Mordehai, T.
Deposit date:2024-04-04
Release date:2024-04-24
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge.
Npj Vaccines, 9, 2024
7CM1
DownloadVisualize
BU of 7cm1 by Molmil
Neuraminidase from the Wuhan Asiatic toad influenza virus
Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase
Authors:Wang, J.
Deposit date:2020-07-23
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Lattice-translocation defects in specific crystals of the catalytic head domain of influenza neuraminidase.
Acta Crystallogr D Struct Biol, 76, 2020
3BEQ
DownloadVisualize
BU of 3beq by Molmil
Neuraminidase of A/Brevig Mission/1/1918 H1N1 strain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:Xu, X, Zhu, X, Wilson, I.A.
Deposit date:2007-11-19
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
7E6Q
DownloadVisualize
BU of 7e6q by Molmil
Crystal structure of influenza A virus neuraminidase N5 complexed with 4'-phenyl-1,2,3-triazolylated oseltamivir carboxylate
Descriptor: (3R,4R,5S)-4-acetamido-3-pentan-3-yloxy-5-(4-phenyl-1,2,3-triazol-1-yl)cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Wang, P.F, Babayemi, O.O, Li, C.N, Fu, L.F, Zhang, S.S, Qi, J.X, Lv, X, Li, X.B.
Deposit date:2021-02-23
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based design of 5'-substituted 1,2,3-triazolylated oseltamivir derivatives as potent influenza neuraminidase inhibitors.
Rsc Adv, 11, 2021
3B7E
DownloadVisualize
BU of 3b7e by Molmil
Neuraminidase of A/Brevig Mission/1/1918 H1N1 strain in complex with zanamivir
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Xu, X, Zhu, X, Wilson, I.A.
Deposit date:2007-10-30
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
6N4D
DownloadVisualize
BU of 6n4d by Molmil
The crystal structure of neuramindase from A/canine/IL/11613/2015 (H3N2) influenza virus.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yang, H, Stevens, J.
Deposit date:2018-11-19
Release date:2019-01-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Assessment of Molecular, Antigenic, and Pathological Features of Canine Influenza A(H3N2) Viruses That Emerged in the United States.
J. Infect. Dis., 216, 2017
8GAV
DownloadVisualize
BU of 8gav by Molmil
Structure of human NDS.3 Fab in complex with influenza virus neuraminidase from A/Darwin/09/2021 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab NDS.3, heavy chain, ...
Authors:Tsybovsky, Y, Lederhofer, J, Kwong, P.D, Kanekiyo, M.
Deposit date:2023-02-23
Release date:2024-02-28
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase.
Immunity, 57, 2024
6N6B
DownloadVisualize
BU of 6n6b by Molmil
The complex crystal structure of neuraminidase from A/Minnesota/11/2010 with B10 antibody.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B10 antibody Heavy Chain Fab, B10 antibody Light Chain Fab, ...
Authors:Yang, H, Stevens, J.
Deposit date:2018-11-26
Release date:2019-07-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain.
Nat Microbiol, 4, 2019
6NN9
DownloadVisualize
BU of 6nn9 by Molmil
REFINED ATOMIC STRUCTURES OF N9 SUBTYPE INFLUENZA VIRUS NEURAMINIDASE AND ESCAPE MUTANTS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE N9, ...
Authors:Tulip, W.R, Varghese, J.N, Baker, A.T, Vandonkelaar, A, Laver, W.G, Webster, R.G, Colman, P.M.
Deposit date:1991-03-28
Release date:1992-07-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined atomic structures of N9 subtype influenza virus neuraminidase and escape mutants.
J.Mol.Biol., 221, 1991
7FGD
DownloadVisualize
BU of 7fgd by Molmil
A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus
Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, toad NA (OSE)
Authors:Chai, Y, Wu, Y, Gao, F.
Deposit date:2021-07-26
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7FGC
DownloadVisualize
BU of 7fgc by Molmil
A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus
Descriptor: CALCIUM ION, ZANAMIVIR, toad NA (ZMR)
Authors:Chai, Y, Wu, Y, Gao, F.
Deposit date:2021-07-26
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7FGB
DownloadVisualize
BU of 7fgb by Molmil
A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, SULFATE ION, ...
Authors:Chai, Y, Wu, Y, Gao, F.
Deposit date:2021-07-26
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
6U02
DownloadVisualize
BU of 6u02 by Molmil
CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-13
Release date:2019-12-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
8U1C
DownloadVisualize
BU of 8u1c by Molmil
A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-400 heavy chain, ...
Authors:Ferguson, J.A, Oeverdieck, S, Ward, A.B.
Deposit date:2023-08-31
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
To Be Published
8U1S
DownloadVisualize
BU of 8u1s by Molmil
A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-393 heavy chain, ...
Authors:Ferguson, J.A, Raghavan, S.S.R, Ward, A.B.
Deposit date:2023-09-02
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
To Be Published
8U1Q
DownloadVisualize
BU of 8u1q by Molmil
A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-2D10 heavy chain, ...
Authors:Ferguson, J.A, Oeverdieck, S, Ward, A.B.
Deposit date:2023-09-01
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
To Be Published
6V4O
DownloadVisualize
BU of 6v4o by Molmil
Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-11-28
Release date:2020-10-07
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
6V4N
DownloadVisualize
BU of 6v4n by Molmil
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-11-28
Release date:2020-10-07
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
1V0Z
DownloadVisualize
BU of 1v0z by Molmil
Structure of Neuraminidase from English duck subtype N6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Rudino-Pinera, E, Tunnah, P, Crennell, S.J, Webster, R.G, Laver, W.G, Garman, E.F.
Deposit date:2004-03-12
Release date:2006-01-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The Crystal Structure of Influenza Type a Virus Neuraminidase of the N6 Subtype at 1.85 A Resolution
To be Published
1VCJ
DownloadVisualize
BU of 1vcj by Molmil
Influenza B virus neuraminidase complexed with 1-(4-Carboxy-2-(3-pentylamino)phenyl)-5-aminomethyl-5-hydroxymethyl-pyrrolidin-2-one
Descriptor: 4-[(2R)-2-(AMINOMETHYL)-2-(HYDROXYMETHYL)-5-OXOPYRROLIDIN-1-YL]-3-[(1-ETHYLPROPYL)AMINO]BENZOIC ACID, NEURAMINIDASE
Authors:Lommer, B.S, Ali, S.M, Bajpai, S.N, Brouillette, W.J, Air, G.M, Luo, M.
Deposit date:2004-03-09
Release date:2004-03-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase.
Acta Crystallogr.,Sect.D, 60, 2004

225158

数据于2024-09-18公开中

PDB statisticsPDBj update infoContact PDBjnumon