1CID
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5U1F
| Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145 | 分子名称: | BG505 DS-SOSIP gp120, BG505 SOSIP gp41, PGT145 heavy chain, ... | 著者 | Acharya, P, Kwong, P.D, Potter, C.S, Carragher, B. | 登録日 | 2016-11-28 | 公開日 | 2017-02-22 | 最終更新日 | 2018-10-03 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer. Nat. Struct. Mol. Biol., 24, 2017
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3T0E
| Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4 | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | 著者 | Yin, Y, Mariuzza, R.A. | 登録日 | 2011-07-20 | 公開日 | 2012-03-07 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proc.Natl.Acad.Sci.USA, 109, 2012
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6MET
| Structural basis of coreceptor recognition by HIV-1 envelope spike | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shaik, M.M, Chen, B. | 登録日 | 2018-09-07 | 公開日 | 2018-12-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural basis of coreceptor recognition by HIV-1 envelope spike. Nature, 565, 2018
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7T0R
| Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adnectin 6940_B01, Ibalizumab Heavy Chain, ... | 著者 | Williams, S.P, Concha, N.O, Wensel, D.L, Hong, X. | 登録日 | 2021-11-30 | 公開日 | 2022-01-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment. J.Mol.Biol., 434, 2021
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7T0O
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8FYJ
| Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | 著者 | Fan, C, Dam, K.A, Bjorkman, P.J. | 登録日 | 2023-01-26 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers. Nature, 623, 2023
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8FYI
| Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Fan, C, Dam, K.A, Bjorkman, P.J. | 登録日 | 2023-01-26 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers. Nature, 623, 2023
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1WIP
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1WIO
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1WIQ
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