3LEH
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3SQZ
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7CQT
| Crystal structure of Brassica juncea HMG-CoA synthase 1 mutant - S359A in complex with acetyl-CoA | 分子名称: | 3-hydroxy-3-methylglutaryl coenzyme A synthase, ACETYL COENZYME *A, ADENOSINE-3'-5'-DIPHOSPHATE | 著者 | Liao, P, Hu, M, Kong, G.K.W, Hao, Q, Chye, M.L. | 登録日 | 2020-08-11 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Overexpression and Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA Synthase Affect Central Metabolic Pathways in Tobacco. Plant Cell.Physiol., 62, 2021
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2P8U
| Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I | 分子名称: | COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | 著者 | Turnbull, A, Shafqat, N, Salah, E, Niesen, F.H, Burgess, N, Bunkoczi, G, Debreczeni, J, Pike, A.C.W, Umeano, C, Gorrec, F, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2007-03-23 | 公開日 | 2007-04-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. J.Mol.Biol., 398, 2010
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2F82
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2WYA
| CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL 3-HYDROXY-3-METHYLGLUTARYL- COENZYME A SYNTHASE 2 (HMGCS2) | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, GLYCEROL, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, ... | 著者 | Yue, W.W, Shafqat, N, Savitsky, P, Roos, A.K, Cooper, C, Murray, J.W, von Delft, F, Arrowsmith, C, Wikstrom, M, Edwards, A, Bountra, C, Oppermann, U. | 登録日 | 2009-11-13 | 公開日 | 2009-11-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structures of Human Hmg-Coa Synthase Isoforms Provide Insights Into Inherited Ketogenesis Disorders and Inhibitor Design. J.Mol.Biol., 398, 2010
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1TVZ
| Crystal structure of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Staphylococcus aureus | 分子名称: | 3-hydroxy-3-methylglutaryl-CoA synthase, SULFATE ION | 著者 | Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M. | 登録日 | 2004-06-30 | 公開日 | 2004-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism J.Biol.Chem., 279, 2004
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1TXT
| Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase | 分子名称: | 3-hydroxy-3-methylglutaryl-CoA synthase, ACETOACETYL-COENZYME A | 著者 | Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M. | 登録日 | 2004-07-06 | 公開日 | 2004-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism J.Biol.Chem., 279, 2004
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4YXT
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4YXQ
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3V4X
| The Biochemical and Structural Basis for Inhibition of Enterococcus faecalis HMG-CoA Synthase, mvaS, by Hymeglusin | 分子名称: | (7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid, HMG-CoA synthase | 著者 | Skaff, D.A, Ramyar, K.X, McWhorter, W.J, Geisbrecht, B.V, Miziorko, H.M. | 登録日 | 2011-12-15 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Biochemical and structural basis for inhibition of Enterococcus faecalis hydroxymethylglutaryl-CoA synthase, mvaS, by hymeglusin. Biochemistry, 51, 2012
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3V4N
| The Biochemical and Structural Basis for Inhibition of Enterococcus faecalis HMG-CoA Synthatse, mvaS, by Hymeglusin | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HMG-CoA synthase | 著者 | Skaff, D.A, Ramyar, K.X, McWhorter, W.J, Geisbrecht, B.V, Miziorko, H.M. | 登録日 | 2011-12-15 | 公開日 | 2012-04-25 | 最終更新日 | 2014-09-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Biochemical and structural basis for inhibition of Enterococcus faecalis hydroxymethylglutaryl-CoA synthase, mvaS, by hymeglusin. Biochemistry, 51, 2012
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4YXV
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2FA0
| HMG-CoA synthase from Brassica juncea in complex with HMG-CoA and covalently bound to HMG-CoA | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, HMG-CoA synthase | 著者 | Pojer, F, Ferrer, J.L, Richard, S.B, Noel, J.P. | 登録日 | 2005-12-06 | 公開日 | 2006-07-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc.Natl.Acad.Sci.Usa, 103, 2006
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5KP8
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5KP5
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5KP7
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5HWO
| MvaS in complex with 3-hydroxy-3-methylglutaryl coenzyme A | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | 著者 | Bock, T, Kasten, J, Blankenfeldt, W. | 登録日 | 2016-01-29 | 公開日 | 2016-05-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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5KP6
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5HWP
| MvaS with acetylated Cys115 in complex with coenzyme A | 分子名称: | COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | 著者 | Bock, T, Kasten, J, Blankenfeldt, W. | 登録日 | 2016-01-29 | 公開日 | 2016-05-11 | 最終更新日 | 2016-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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5HWR
| MvaS in complex with coenzyme A | 分子名称: | COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | 著者 | Bock, T, Kasten, J, Blankenfeldt, W. | 登録日 | 2016-01-29 | 公開日 | 2016-05-11 | 最終更新日 | 2016-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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5HWQ
| MvaS in complex with acetoacetyl coenzyme A | 分子名称: | ACETOACETYL-COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | 著者 | Bock, T, Kasten, J, Blankenfeldt, W. | 登録日 | 2016-01-29 | 公開日 | 2016-05-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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2F9A
| HMG-CoA synthase from Brassica juncea in complex with F-244 | 分子名称: | (7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid, 3-Hydroxy-3-methylglutaryl coenzyme A synthase 1 | 著者 | Pojer, F, Ferrer, J.L, Richard, S.B, Noel, J.P. | 登録日 | 2005-12-05 | 公開日 | 2006-07-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2FA3
| HMG-CoA synthase from Brassica juncea in complex with acetyl-CoA and acetyl-cys117. | 分子名称: | ACETYL COENZYME *A, HMG-CoA synthase | 著者 | Pojer, F, Ferrer, J.L, Richard, S.B, Noel, J.P. | 登録日 | 2005-12-06 | 公開日 | 2006-07-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HDB
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