PDB: 75 件ウェブページステータス検索Chemie searchBIRD

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2AB5	bI3 LAGLIDADG Maturase 分子名称: SULFATE ION, mRNA maturase 著者 Longo, A, Leonard, C.W, Bassi, G.S, Berndt, D, Krahn, J.M, Hall, T.M, Weeks, K.M. 登録日 2005-07-14 公開日 2005-08-30 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase Nat.Struct.Mol.Biol., 12, 2005
3KO2	I-MsoI re-designed for altered DNA cleavage specificity (-7C) 分子名称: 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*GP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*CP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... 著者 Taylor, G.K, Stoddard, B.L. 登録日 2009-11-13 公開日 2010-05-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38, 2010
4EFJ	Crystal structure of I-GzeII LAGLIDADG homing endonuclease in complex with DNA target site 分子名称: CALCIUM ION, DNA target site bottom strand, DNA target site top strand, ... 著者 Kulshina, N. 登録日 2012-03-29 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of I-GzeMII LAGLIDADG homing endonuclease in complex with DNA target site To be Published
4YIT	Crystal Structure of LAGLIDADG Meganuclease I-AabMI Bound to Uncleaved DNA 分子名称: CALCIUM ION, DNA (25-MER), DNA (25MER), ... 著者 Hallinan, J.P, Stoddard, B.L. 登録日 2015-03-02 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.24 Å) 主引用文献 Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure, 24, 2016
5GKK	Crystal structure of a homing endonuclease, I-TnaI 分子名称: Putative homing endonuclease 著者 Ren, J. 登録日 2016-07-04 公開日 2017-07-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Crystal structure of a homing endonuclease, I-TnaI To Be Published
2O7M	The C-terminal loop of the homing endonuclease I-CreI is essential for DNA binding and cleavage. Identification of a novel site for specificity engineering in the I-CreI scaffold 分子名称: DNA endonuclease I-CreI 著者 Prieto, J, Redondo, P, Padro, D, Blanco, F.J, Paques, F, Montoya, G. 登録日 2006-12-11 公開日 2007-10-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage Nucleic Acids Res., 35, 2007
4LOX	Crystal structure of the I-SmaMI LAGLIDADG homing endonuclease bound to cleaved DNA 分子名称: DNA (5'-D(*CP*GP*TP*AP*CP*AP*CP*CP*TP*GP*AP*TP*AP*A)-3'), DNA (5'-D(*GP*GP*TP*AP*TP*CP*CP*TP*CP*CP*AP*TP*TP*AP*T)-3'), DNA (5'-D(P*CP*AP*GP*GP*TP*GP*TP*AP*CP*G)-3'), ... 著者 Chik, J, Shen, B, Stoddard, B. 登録日 2013-07-14 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal structure of a LAGLIDADG endonuclease from the Sordaria Macrospore. To be Published
1AF5	GROUP I MOBILE INTRON ENDONUCLEASE 分子名称: I-CREI 著者 Heath, P.J, Stephens, K.M, Monnat Junior, R.J, Stoddard, B.L. 登録日 1997-03-21 公開日 1997-07-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of I-Crel, a group I intron-encoded homing endonuclease. Nat.Struct.Biol., 4, 1997
2I3P	K28R mutant of Homing Endonuclease I-CreI 分子名称: 5'-D(*CP*GP*AP*AP*AP*TP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*AP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*TP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*AP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... 著者 Sussman, D, Rosen, L. 登録日 2006-08-20 公開日 2006-09-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Homing endonuclease I-CreI derivatives with novel DNA target specificities. Nucleic Acids Res., 34, 2006
4LQ0	Crystal structure of the I-LtrWI LAGLIDADG homing endonuclease bound to target DNA. 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Chik, J, Shen, B, Stoddard, B. 登録日 2013-07-16 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Structural Comparisons of LAGLIDADG Homing Endonucleases. To be Published
2I3Q	Q44V mutant of Homing Endonuclease I-CreI 分子名称: 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*AP*CP*TP*CP*AP*CP*GP*TP*CP*GP*TP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*AP*CP*GP*TP*GP*AP*GP*TP*CP*AP*GP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... 著者 Rosen, L, Sussman, D. 登録日 2006-08-20 公開日 2006-09-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Homing endonuclease I-CreI derivatives with novel DNA target specificities. Nucleic Acids Res., 34, 2006
1BP7	GROUP I MOBILE INTRON ENDONUCLEASE I-CREI COMPLEXED WITH HOMING SITE DNA 分子名称: CALCIUM ION, DNA (5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP* GP*C)-3'), DNA (5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP* CP*G)-3'), ... 著者 Jurica, M.S, Monnat Junior, R.J, Stoddard, B.L. 登録日 1998-08-13 公開日 1999-01-06 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI. Mol.Cell, 2, 1998
3QQY	Crystal structure of a novel LAGLIDADG homing endonuclease, I-OnuI (from Ophiostoma novo-ulmi subsp. americana) 分子名称: DNA (26-MER), MAGNESIUM ION, Ribosomal protein 3/homing endonuclease-like protein fusion 著者 Takeuchi, R, Stoddard, B.L. 登録日 2011-02-16 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Tapping natural reservoirs of homing endonucleases for targeted gene modification. Proc.Natl.Acad.Sci.USA, 108, 2011
1G9Y	HOMING ENDONUCLEASE I-CREI / DNA SUBSTRATE COMPLEX WITH CALCIUM 分子名称: 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... 著者 Chevalier, B, Monnat, R.J, Stoddard, B.L. 登録日 2000-11-28 公開日 2001-04-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites. Nat.Struct.Biol., 8, 2001
1G9Z	LAGLIDADG HOMING ENDONUCLEASE I-CREI / DNA PRODUCT COMPLEX WITH MAGNESIUM 分子名称: 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*A)-3', 5'-D(P*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', ... 著者 Chevalier, B, Monnat, R.J, Stoddard, B.L. 登録日 2000-11-28 公開日 2001-04-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites. Nat.Struct.Biol., 8, 2001
2EX5	Group I Intron-encoded Homing Endonuclease I-CeuI Complexed With DNA 分子名称: CALCIUM ION, DNA endonuclease I-CeuI, I-CeuI DNA target site, ... 著者 Spiegel, P.C, Stoddard, B.L. 登録日 2005-11-07 公開日 2006-05-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of I-CeuI homing endonuclease: Evolving asymmetric DNA recognition from a symmetric protein scaffold. Structure, 14, 2006
2FLD	I-MsoI Re-Designed for Altered DNA Cleavage Specificity 分子名称: 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... 著者 Ashworth, J, Duarte, C.M, Havranek, J.J, Sussman, D, Monnat, R.J, Stoddard, B.L, Baker, D. 登録日 2006-01-05 公開日 2006-06-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Computational redesign of endonuclease DNA binding and cleavage specificity. Nature, 441, 2006
3R7P	The crystal structure of I-LtrI 分子名称: DNA (5'-D(*CP*AP*AP*AP*TP*GP*CP*TP*CP*CP*TP*AP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*GP*CP*AP*TP*TP*TP*G)-3'), ... 著者 Mak, A.N.S, Takeuchi, R, Edgell, D.R, Stoddard, B.L. 登録日 2011-03-22 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 Tapping natural reservoirs of homing endonucleases for targeted gene modification. Proc.Natl.Acad.Sci.USA, 108, 2011
6FB1	Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in complex with its target DNA (Haemoglobin beta subunit gene) in the presence of Magnesium 分子名称: DNA (5'-D(*TP*CP*AP*GP*AP*CP*TP*TP*CP*TP*CP*CP*AP*C)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*CP*TP*CP*CP*TP*GP*TP*GP*G)-3'), DNA (5'-D(P*AP*GP*AP*AP*GP*TP*CP*TP*GP*A)-3'), ... 著者 Molina, R, Prieto, J. 登録日 2017-12-18 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.024 Å) 主引用文献 Understanding the indirect DNA read-out specificity of I-CreI Meganuclease. Sci Rep, 8, 2018
6FB8	Crystal Structure of the I-CreI Homing Endonuclease D75N variant in complex with an altered version of its target DNA at 5NNN region in the presence of Magnesium 分子名称: DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*CP*GP*CP*AP*GP*TP*TP*TP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*TP*GP*CP*GP*TP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3'), DNA endonuclease I-CreI, ... 著者 Molina, R, Prieto, J. 登録日 2017-12-18 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Understanding the indirect DNA read-out specificity of I-CreI Meganuclease. Sci Rep, 8, 2018
6FB7	Crystal Structure of the I-CreI Homing Endonuclease D75N variant in complex with its target DNA in the presence of Manganese 分子名称: DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3'), DNA endonuclease I-CreI, ... 著者 Molina, R, Prieto, J. 登録日 2017-12-18 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.689 Å) 主引用文献 Understanding the indirect DNA read-out specificity of I-CreI Meganuclease. Sci Rep, 8, 2018
3E54	Archaeal Intron-encoded Homing Endonuclease I-Vdi141I Complexed With DNA 分子名称: DNA (5'-D(*DCP*DTP*DGP*DAP*DCP*DTP*DCP*DTP*DCP*DTP*DTP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DGP*DGP*DCP*DTP*DAP*DCP*DCP*DTP*DTP*DAP*DA)-3'), DNA (5'-D(P*DGP*DAP*DGP*DAP*DGP*DTP*DCP*DAP*DG)-3'), ... 著者 Nomura, N, Nomura, Y, Sussman, D, Stoddard, B.L. 登録日 2008-08-13 公開日 2008-12-30 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Recognition of a common rDNA target site in archaea and eukarya by analogous LAGLIDADG and His-Cys box homing endonucleases Nucleic Acids Res., 36, 2008
3EH8	Crystal structure of Y2 I-AniI variant (F13Y/S111Y)/DNA complex with calcium 分子名称: 31-MER, CALCIUM ION, Intron-encoded DNA endonuclease I-AniI 著者 Takeuchi, R, Stoddard, B.L. 登録日 2008-09-11 公開日 2009-01-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation. Nucleic Acids Res., 37, 2009
3FD2	Crystal structure of mMsoI/DNA complex with calcium 分子名称: 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... 著者 Li, H, Monnat, R.J. 登録日 2008-11-24 公開日 2009-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins. Nucleic Acids Res., 37, 2009
1U0C	Y33C Mutant of Homing endonuclease I-CreI 分子名称: 5'-D(*CP*GP*TP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*AP*GP*C)-3', 5'-D(*GP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*AP*CP*G)-3', DNA endonuclease I-CreI, ... 著者 Sussman, D, Chadsey, M, Fauce, S, Engel, A, Bruett, A, Monnat, R, Stoddard, B.L, Seligman, L.M. 登録日 2004-07-13 公開日 2004-11-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Isolation and characterization of new homing endonuclease specificities at individual target site positions. J.Mol.Biol., 342, 2004

 

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