2I3Q

Q44V mutant of Homing Endonuclease I-CreI

Summary for 2I3Q

• Entry DOI: 10.2210/pdb2i3q/pdb
• Related: 2I3P
• Descriptor: 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*AP*CP*GP*TP*GP*AP*GP*TP*CP*AP*GP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*AP*CP*TP*CP*AP*CP*GP*TP*CP*GP*TP*TP*TP*TP*GP*C)-3', DNA endonuclease I-CreI, ... (5 entities in total)
• Functional Keywords: homing endonuclease, i-crei, hydrolase-dna complex, hydrolase/dna
• Biological source: Chlamydomonas reinhardtii
• Cellular location: Plastid, chloroplast: P05725
• Total number of polymer chains: 4
• Total formula weight: 49940.12

Authors

Rosen, L.,Sussman, D. (deposition date: 2006-08-20, release date: 2006-09-05, Last modification date: 2023-08-30)

• Primary citation: Rosen, L.E.,Morrison, H.A.,Masri, S.,Brown, M.J.,Springstubb, B.,Sussman, D.,Stoddard, B.L.,Seligman, L.M.; Homing endonuclease I-CreI derivatives with novel DNA target specificities.; Nucleic Acids Res., 34:4791-4800, 2006; PubMed: 16971456; DOI: 10.1093/nar/gkl645

Experimental method

X-RAY DIFFRACTION (2.3 Å)