PDB: 122 件ウェブページステータス検索Chemie searchBIRD

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2WZK	Structure of the Cul5 N-terminal domain at 2.05A resolution. 分子名称: 1,2-ETHANEDIOL, CULLIN-5 著者 Muniz, J.R.C, Ayinampudi, V, Zhang, Y, Babon, J.J, Chaikuad, A, Krojer, T, Pike, A.C.W, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bullock, A.N. 登録日 2009-11-30 公開日 2009-12-15 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases J.Mol.Biol., 425, 2013
4A64	Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution 分子名称: 1,2-ETHANEDIOL, CULLIN-4B 著者 Vollmar, M, Ayinampudi, V, Cooper, C, Guo, K, Krojer, T, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Bullock, A. 登録日 2011-10-31 公開日 2012-02-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Crystal Structure of the N-Terminal Domain of Human Cul4B at 2.57A Resolution To be Published
8EI1	Crystal structure of the N-terminal domain of CUL4B in complex with H316, a Helicon Polypeptide 分子名称: Cullin-4B, H316, N,N'-(1,4-phenylene)diacetamide 著者 Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. 登録日 2022-09-14 公開日 2023-10-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
8EI2	Crystal structure of the N-terminal domain of CUL5 in complex with H314, a Helicon Polypeptide 分子名称: Cullin-5, H314, N,N'-(1,4-phenylene)diacetamide 著者 Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. 登録日 2022-09-14 公開日 2023-10-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
3RTR	A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases 分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION 著者 Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A. 登録日 2011-05-03 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases. Nat.Struct.Mol.Biol., 18, 2011
1U6G	Crystal Structure of The Cand1-Cul1-Roc1 Complex 分子名称: Cullin homolog 1, RING-box protein 1, TIP120 protein, ... 著者 Goldenberg, S.J, Shumway, S.D, Cascio, T.C, Garbutt, K.C, Liu, J, Xiong, Y, Zheng, N. 登録日 2004-07-29 公開日 2004-12-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases Cell(Cambridge,Mass.), 119, 2004
2HYE	Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex 分子名称: Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ... 著者 Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N. 登録日 2006-08-05 公開日 2006-10-03 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature, 443, 2006
6V9I	cryo-EM structure of Cullin5 bound to RING-box protein 2 (Cul5-Rbx2) 分子名称: Immunoglobulin G-binding protein G,Cullin-5, RING-box protein 2, ZINC ION 著者 Komives, E.A, Lumpkin, R.J, Baker, R.W, Leschziner, A.E. 登録日 2019-12-13 公開日 2020-04-29 最終更新日 2020-11-11 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Structure and dynamics of the ASB9 CUL-RING E3 Ligase. Nat Commun, 11, 2020
3DPL	Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation. 分子名称: Cullin-5, RING-box protein 1, ZINC ION 著者 Duda, D.M, Schulman, B.A. 登録日 2008-07-08 公開日 2008-09-30 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134, 2008
1LDK	Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex 分子名称: CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ... 著者 Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P. 登録日 2002-04-08 公開日 2002-05-08 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature, 416, 2002
1LDJ	Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex 分子名称: Cullin homolog 1, ZINC ION, ring-box protein 1 著者 Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P. 登録日 2002-04-08 公開日 2002-05-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature, 416, 2002
8CDK	CAND1 b-hairpin++-SCF-SKP2 CAND1 partly engaged SCF partly rocked 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Schulman, B.A. 登録日 2023-01-31 公開日 2023-04-19 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
8CDJ	CAND1 b-hairpin++-SCF-SKP2 CAND1 rolling SCF engaged 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Schulman, B.A. 登録日 2023-01-31 公開日 2023-04-19 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
4F52	Structure of a Glomulin-RBX1-CUL1 complex 分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ... 著者 Duda, D.M, Olszewski, J.L, Schulman, B.A. 登録日 2012-05-11 公開日 2012-09-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface. Mol.Cell, 47, 2012
7OKQ	Cryo-EM Structure of the DDB1-DCAF1-CUL4A-RBX1 Complex 分子名称: Cullin-4A, DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, ... 著者 Mohamed, W.I, Schenk, A.D, Kempf, G, Cavadini, S, Thoma, N.H. 登録日 2021-05-18 公開日 2021-10-13 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (8.4 Å) 主引用文献 The CRL4 DCAF1 cullin-RING ubiquitin ligase is activated following a switch in oligomerization state. Embo J., 40, 2021
4A0C	Structure of the CAND1-CUL4B-RBX1 complex 分子名称: CULLIN-4B, CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1, E3 UBIQUITIN-PROTEIN LIGASE RBX1, ... 著者 Scrima, A, Fischer, E.S, Faty, M, Gut, H, Thoma, N.H. 登録日 2011-09-08 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation Cell(Cambridge,Mass.), 147, 2011
7Z8T	CAND1-SCF-SKP2 CAND1 engaged SCF rocked 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Schulman, B.A. 登録日 2022-03-18 公開日 2023-04-19 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
7Z8R	CAND1-CUL1-RBX1 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Schulman, B.A. 登録日 2022-03-18 公開日 2023-04-19 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
7ZBZ	CAND1 delhairpin-SCF-SKP2 CAND1 partly engaged SCF partly rocked 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Schulman, B.A. 登録日 2022-03-24 公開日 2023-04-19 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
7ZBW	CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Schulman, B.A. 登録日 2022-03-24 公開日 2023-04-19 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
7Z8V	CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Schulman, B.A. 登録日 2022-03-18 公開日 2023-04-19 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
8H3Q	Cryo-EM Structure of the CAND1-Cul3-Rbx1 complex 分子名称: Cullin-3, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... 著者 Hu, Y, Mao, Q, Chen, Z, Sun, L. 登録日 2022-10-09 公開日 2023-10-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
8U80	KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(BTB)/Cullin3(NTD) 分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3 著者 Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G. 登録日 2023-09-15 公開日 2023-10-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure and dynamics of a pentameric KCTD5/Cullin3/G beta gamma E3 ubiquitin ligase complex Proc.Natl.Acad.Sci.USA, 2024
8I79	Cryo-EM structure of KCTD7 in complex with Cullin3 分子名称: BTB/POZ domain-containing protein KCTD7, Cullin-3 著者 Jiang, W, Wang, W, Zheng, S. 登録日 2023-01-31 公開日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for the ubiquitination of G protein beta gamma subunits by KCTD5/Cullin3 E3 ligase. Sci Adv, 9, 2023
8OR2	CAND1-CUL1-RBX1-DCNL1 分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, DCN1-like protein 1, ... 著者 Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I. 登録日 2023-04-12 公開日 2023-06-28 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange. Mol.Cell, 83, 2023

 

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