1AMO
| THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Wang, M, Roberts, D.L, Paschke, R, Shea, T.M, Masters, B.S.S, Kim, J.J.P. | 登録日 | 1997-06-17 | 公開日 | 1998-06-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes. Proc.Natl.Acad.Sci.USA, 94, 1997
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4YAW
| Reduced CYPOR mutant - G141del | 分子名称: | ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Xia, C, Kim, J.J.P. | 登録日 | 2015-02-17 | 公開日 | 2016-03-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone. J.Biol.Chem., 291, 2016
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5GXU
| Cystal structure of Arabidopsis ATR2 | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH--cytochrome P450 reductase 2 | 著者 | Niu, G, Liu, L. | 登録日 | 2016-09-20 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Arabidopsis thaliana NADPH-cytochrome P450 reductase 2 (ATR2) provides insight into its function FEBS J., 284, 2017
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6NJR
| Spin-Labeled T177C/A637C Mutant of Rat CYPOR | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xia, C, Kim, J.J.K. | 登録日 | 2019-01-04 | 公開日 | 2019-02-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Functional Studies of the Membrane-Binding Domain of NADPH-Cytochrome P450 Oxidoreductase. Biochemistry, 58, 2019
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7L18
| Crystal structure of a tandem deletion mutant of rat NADPH-cytochrome P450 reductase | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Hubbard, P.A, Xia, C, Shen, A.L, Kim, J.J.K. | 登録日 | 2020-12-14 | 公開日 | 2021-01-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.542 Å) | 主引用文献 | Structural and kinetic investigations of the carboxy terminus of NADPH-cytochrome P450 oxidoreductase. Arch.Biochem.Biophys., 701, 2021
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6EFV
| The NADPH-dependent sulfite reductase flavoprotein adopts an extended conformation that is unique to this diflavin reductase | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Tavolieri, A.M, Askenasy, I, Murray, D.T, Pennington, J.M, Stroupe, M.E. | 登録日 | 2018-08-17 | 公開日 | 2019-02-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | 主引用文献 | NADPH-dependent sulfite reductase flavoprotein adopts an extended conformation unique to this diflavin reductase. J. Struct. Biol., 205, 2019
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3WKT
| Complex structure of an open form of NADPH-cytochrome P450 reductase and heme oxygenase-1 | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1, ... | 著者 | Sugishima, M, Sato, H, Higashimoto, Y, Harada, J, Wada, K, Fukuyama, K, Noguchi, M. | 登録日 | 2013-10-31 | 公開日 | 2014-01-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Structural basis for the electron transfer from an open form of NADPH-cytochrome P450 oxidoreductase to heme oxygenase. Proc.Natl.Acad.Sci.USA, 111, 2014
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1TLL
| CRYSTAL STRUCTURE OF RAT NEURONAL NITRIC-OXIDE SYNTHASE REDUCTASE MODULE AT 2.3 A RESOLUTION. | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Garcin, E.D, Bruns, C.M, Lloyd, S.J, Hosfield, D.J, Tiso, M, Gachhui, R, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2004-06-09 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase J.Biol.Chem., 279, 2004
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8DME
| CYP102A1 in Open Conformation | 分子名称: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional cytochrome P450/NADPH--P450 reductase, FLAVIN MONONUCLEOTIDE, ... | 著者 | Su, M, Xu, H. | 登録日 | 2022-07-08 | 公開日 | 2023-07-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Insight into the conformational dynamics of cytochrome P450 CYP102A1 enzyme using Cryo-EM To Be Published
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8DMG
| CYP102A1 in Closed Conformation | 分子名称: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional cytochrome P450/NADPH--P450 reductase, FLAVIN MONONUCLEOTIDE, ... | 著者 | Su, M, Xu, H. | 登録日 | 2022-07-08 | 公開日 | 2023-07-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Insight into the conformational dynamics of cytochrome P450 CYP102A1 enzyme using Cryo-EM To Be Published
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6T1T
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8T1J
| Uncrosslinked nNOS-CaM oxygenase homodimer | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ... | 著者 | Lee, K, Pospiech, T.H, Southworth, D. | 登録日 | 2023-06-02 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry. J.Biol.Chem., 300, 2023
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8T1K
| DSBU crosslinked nNOS-CaM oxygenase homodimer | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ... | 著者 | Lee, K, Pospiech, T.H, Southworth, D. | 登録日 | 2023-06-02 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry. J.Biol.Chem., 300, 2023
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3ES9
| NADPH-Cytochrome P450 Reductase in an Open Conformation | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Hamdane, D, Xia, C, Im, S.-C, Zhang, H, Kim, J.-J, Waskell, L. | 登録日 | 2008-10-05 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure and function of an NADPH-cytochrome P450 oxidoreductase in an open conformation capable of reducing cytochrome P450 J.Biol.Chem., 284, 2009
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4DQL
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5EMN
| Crystal Structure of Human NADPH-Cytochrome P450 Reductase(A287P mutant) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xia, C, Marohnic, C, Panda, S, Masters, B.S, Kim, J.J.K. | 登録日 | 2015-11-06 | 公開日 | 2016-08-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype. J.Biol.Chem., 291, 2016
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6T1U
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4DQK
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3FJO
| Structure of chimeric YH CPR | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH-cytochrome P450 reductase | 著者 | Morera, S, Aigrain, L, Truan, G. | 登録日 | 2008-12-15 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the open conformation of a functional chimeric NADPH cytochrome P450 reductase Embo Rep., 10, 2009
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2QTL
| Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase | 著者 | Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2007-08-02 | 公開日 | 2007-11-13 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry, 46, 2007
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2QTZ
| Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2007-08-02 | 公開日 | 2007-11-13 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry, 46, 2007
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5FA6
| wild type human CYPOR | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xia, C, Marohnic, C, Panda, S, Masters, B.S, Kim, J.J.K. | 登録日 | 2015-12-11 | 公開日 | 2016-08-17 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype. J.Biol.Chem., 291, 2016
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6J79
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1DDI
| CRYSTAL STRUCTURE OF SIR-FP60 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFITE REDUCTASE [NADPH] FLAVOPROTEIN ALPHA-COMPONENT | 著者 | Gruez, A, Pignol, D, Zeghouf, M, Coves, J, Fontecave, M, Ferrer, J.L, Fontecilla-Camps, J.C. | 登録日 | 1999-11-10 | 公開日 | 2000-11-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module. J.Mol.Biol., 299, 2000
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1DDG
| CRYSTAL STRUCTURE OF SIR-FP60 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, SULFITE REDUCTASE (NADPH) FLAVOPROTEIN ALPHA-COMPONENT | 著者 | Gruez, A, Pignol, D, Zeghouf, M, Coves, J, Fontecave, M, Ferrer, J.L, Fontecilla-Camps, J.C. | 登録日 | 1999-11-10 | 公開日 | 2000-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module. J.Mol.Biol., 299, 2000
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