8IZN
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7RCH
| Crystal structure of NS1-ED of Vietnam influenza A virus in complex with the p85-beta-iSH2 domain of human PI3K | 分子名称: | Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta | 著者 | Kim, I, Zhao, B, Li, P, Cho, J.H. | 登録日 | 2021-07-07 | 公開日 | 2022-07-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus. Nat Commun, 13, 2022
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6ZLC
| Non-specific dsRNA recognition by wildtype H7N1 RNA-binding domain | 分子名称: | NITRATE ION, Non-structural protein 1, RNA (5'-R(*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*U)-3'), ... | 著者 | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | 登録日 | 2020-06-30 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
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6U28
| Crystal structure of 1918 NS1-ED W187A in complex with the p85-beta-iSH2 domain of human PI3K | 分子名称: | Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta | 著者 | Cho, J.H, Zhao, B, Savage, N, Li, P. | 登録日 | 2019-08-19 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses. Proc.Natl.Acad.Sci.USA, 117, 2020
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6SX2
| dsRNA recognition by R38AK41A mutant of H7N1 NS1 RNA Binding Domain | 分子名称: | 1,2-ETHANEDIOL, Non-structural protein 1, RNA (5'-R(*GP*GP*UP*AP*AP*CP*UP*GP*UP*UP*AP*CP*AP*GP*UP*UP*AP*CP*C)-3') | 著者 | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | 登録日 | 2019-09-24 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
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6SX0
| Specific dsRNA recognition by wild type H7N1 NS1 RNA-binding domain | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Non-structural protein 1, ... | 著者 | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | 登録日 | 2019-09-24 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
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6SW8
| Crystal structure of the NS1 (H7N1) RNA-binding domain | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Non-structural protein 1 | 著者 | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | 登録日 | 2019-09-20 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.933 Å) | 主引用文献 | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
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6OX7
| The complex of 1918 NS1-ED and the iSH2 domain of the human p85beta subunit of PI3K | 分子名称: | Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta | 著者 | Shen, Q, Zhao, B, Li, P, Cho, J.H. | 登録日 | 2019-05-13 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses. Proc.Natl.Acad.Sci.USA, 117, 2020
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6OQE
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6O01
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6NU0
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6NRL
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6E5U
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6DGK
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5NT2
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5NT1
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5H5N
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5BY1
| H18 Bat Influenza NS1 RNA Binding Domain | 分子名称: | DI(HYDROXYETHYL)ETHER, Non-structural protein 1, PENTAETHYLENE GLYCOL | 著者 | Kerry, P.S, Hale, B.G. | 登録日 | 2015-06-09 | 公開日 | 2015-08-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | 主引用文献 | Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity. J.Virol., 89, 2015
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5BXZ
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4OPH
| X-ray structure of full-length H6N6 NS1 | 分子名称: | Nonstructural protein 1 | 著者 | Carrillo, B, Choi, J.M, Bornholdt, Z.A, Sankaran, S, Rice, A.P, Prasad, B.V.V. | 登録日 | 2014-02-05 | 公開日 | 2014-02-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.158 Å) | 主引用文献 | The Influenza A Virus Protein NS1 Displays Structural Polymorphism. J.Virol., 88, 2014
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4OPA
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3RVC
| Effector domain of NS1 from influenza A/PR/8/34 containing a W187A mutation | 分子名称: | Non-structural protein 1 | 著者 | Kerry, P.S, Long, E, Taylor, M.A, Russell, R.J.M. | 登録日 | 2011-05-06 | 公開日 | 2011-08-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Conservation of a crystallographic interface suggests a role for beta-sheet augmentation in influenza virus NS1 multifunctionality. Acta Crystallogr.,Sect.F, 67, 2011
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3P39
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3P38
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3P31
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