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6MII
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BU of 6mii by Molmil
Crystal structure of minichromosome maintenance protein MCM/DNA complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Enemark, E.J, Meagher, M, Epling, L.B.
登録日2018-09-19
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献DNA translocation mechanism of the MCM complex and implications for replication initiation.
Nat Commun, 10, 2019
5XF8
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BU of 5xf8 by Molmil
Cryo-EM structure of the Cdt1-MCM2-7 complex in AMPPNP state
分子名称: Cell division cycle protein CDT1, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ...
著者Zhai, Y, Cheng, E, Wu, H, Li, N, Yung, P.Y, Gao, N, Tye, B.K.
登録日2017-04-09
公開日2017-05-03
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer
Nat. Struct. Mol. Biol., 24, 2017
5BK4
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BU of 5bk4 by Molmil
Cryo-EM structure of Mcm2-7 double hexamer on dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (60-mer), strand 1, ...
著者Li, H, Yuan, Z, Bai, L.
登録日2017-09-12
公開日2017-10-25
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6HV9
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BU of 6hv9 by Molmil
S. cerevisiae CMG-Pol epsilon-DNA
分子名称: Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ...
著者Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A.
登録日2018-10-10
公開日2018-12-12
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (4.98 Å)
主引用文献Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
4FDG
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BU of 4fdg by Molmil
Crystal Structure of an Archaeal MCM Filament
分子名称: Minichromosome maintenance protein MCM, ZINC ION
著者Slaymaker, I.M, Fu, Y, Brewster, A.B, Chen, X.S.
登録日2012-05-28
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology.
Nucleic Acids Res., 41, 2013
6F0L
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BU of 6f0l by Molmil
S. cerevisiae MCM double hexamer bound to duplex DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (62-MER), DNA replication licensing factor MCM2, ...
著者Abid Ali, F, Pye, V.E, Douglas, M.E, Locke, J, Nans, A, Diffley, J.F.X, Costa, A.
登録日2017-11-20
公開日2017-12-06
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.77 Å)
主引用文献Cryo-EM structure of a licensed DNA replication origin.
Nat Commun, 8, 2017
6EYC
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BU of 6eyc by Molmil
Re-refinement of the MCM2-7 double hexamer using ISOLDE
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ...
著者Croll, T.I.
登録日2017-11-11
公開日2018-06-20
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps.
Acta Crystallogr D Struct Biol, 74, 2018
4R7Z
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BU of 4r7z by Molmil
PfMCM-AAA double-octamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 21, MAGNESIUM ION
著者Miller, J.M, Arachea, B.T, Epling, L.B, Enemark, E.J.
登録日2014-08-28
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Analysis of the crystal structure of an active MCM hexamer.
Elife, 3, 2014
4R7Y
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BU of 4r7y by Molmil
Crystal structure of an active MCM hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Miller, J.M, Arachea, B.T, Epling, L.B, Enemark, E.J.
登録日2014-08-28
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Analysis of the crystal structure of an active MCM hexamer.
Elife, 3, 2014
3F9V
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BU of 3f9v by Molmil
Crystal Structure Of A Near Full-Length Archaeal MCM: Functional Insights For An AAA+ Hexameric Helicase
分子名称: Minichromosome maintenance protein MCM
著者Chen, X.J, Brewster, A.S, Wang, G.G, Yu, X, Greenleaf, W, Tjajadi, M, Klein, M.
登録日2008-11-14
公開日2008-12-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (4.35 Å)
主引用文献Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase.
Proc.Natl.Acad.Sci.USA, 105, 2008
3F8T
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BU of 3f8t by Molmil
Crystal structure analysis of a full-length MCM homolog from Methanopyrus kandleri
分子名称: Predicted ATPase involved in replication control, Cdc46/Mcm family
著者Bae, B, Nair, S.K.
登録日2008-11-13
公開日2009-03-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into the Architecture of the Replicative Helicase from the Structure of an Archaeal MCM Homolog.
Structure, 17, 2009
6SKL
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BU of 6skl by Molmil
Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA fork, ...
著者Yeeles, J, Baretic, D, Jenkyn-Bedford, M.
登録日2019-08-16
公開日2020-05-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 78, 2020
8S94
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BU of 8s94 by Molmil
Structure of C-terminal domains of Walker B mutated MCM8/9 heterohexamer complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA helicase MCM8, DNA helicase MCM9, ...
著者Li, C, Gao, Y.
登録日2023-03-27
公開日2023-06-07
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Activity, substrate preference and structure of the HsMCM8/9 helicase.
Nucleic Acids Res., 51, 2023
8S92
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BU of 8s92 by Molmil
Structure of N-terminal domains of Walker B mutated MCM8/9 heterohexamer complex with ADP
分子名称: DNA helicase MCM8, DNA helicase MCM9
著者Li, C, Gao, Y.
登録日2023-03-27
公開日2023-06-07
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Activity, substrate preference and structure of the HsMCM8/9 helicase.
Nucleic Acids Res., 51, 2023
8S91
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BU of 8s91 by Molmil
Structure of Walker B mutated MCM8/9 heterohexamer complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA helicase MCM8, DNA helicase MCM9, ...
著者Li, C, Gao, Y.
登録日2023-03-27
公開日2023-06-07
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Activity, substrate preference and structure of the HsMCM8/9 helicase.
Nucleic Acids Res., 51, 2023
7QHS
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BU of 7qhs by Molmil
S. cerevisiae CMGE nucleating origin DNA melting
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ...
著者Lewis, J.S, Sousa, J.S, Costa, A.
登録日2021-12-14
公開日2022-06-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of replication origin melting nucleated by CMG helicase assembly.
Nature, 606, 2022
6U0M
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BU of 6u0m by Molmil
Structure of the S. cerevisiae replicative helicase CMG in complex with a forked DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (15-MER), ...
著者Yuan, Z, Georgescu, R, Bai, L, Zhang, D, O'Donnell, M, Li, H.
登録日2019-08-14
公開日2020-03-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA unwinding mechanism of a eukaryotic replicative CMG helicase.
Nat Commun, 11, 2020
5U8T
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BU of 5u8t by Molmil
Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications
分子名称: Cell division control protein 45, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication complex GINS protein PSF1, ...
著者Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, Li, H, O'Donnell, M.E.
登録日2016-12-15
公開日2017-02-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6SKO
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BU of 6sko by Molmil
Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork - conformation 2 MCM CTD:ssDNA
分子名称: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ...
著者Yeeles, J, Baretic, D, Jenkyn-Bedford, M.
登録日2019-08-16
公開日2020-05-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 78, 2020
5U8S
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BU of 5u8s by Molmil
Structure of eukaryotic CMG helicase at a replication fork
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (26-MER), ...
著者Li, H, Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, O'Donnell, M.E.
登録日2016-12-14
公開日2017-01-25
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (6.101 Å)
主引用文献Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3JC7
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BU of 3jc7 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
登録日2015-11-24
公開日2016-02-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3JA8
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BU of 3ja8 by Molmil
Cryo-EM structure of the MCM2-7 double hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
著者Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
登録日2015-05-09
公開日2015-08-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
3JC5
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BU of 3jc5 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
登録日2015-11-24
公開日2016-02-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3JC6
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BU of 3jc6 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
登録日2015-11-24
公開日2016-02-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
8W7S
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BU of 8w7s by Molmil
Yeast replisome in state IV
分子名称: Cell division control protein 45, DNA (71-mer), DNA polymerase alpha-binding protein, ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D.
登録日2023-08-31
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (7.39 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023

 

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