PDB: 238 件ウェブページステータス検索Chemie searchBIRD

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1QC5	I Domain from Integrin Alpha1-Beta1 分子名称: MAGNESIUM ION, PROTEIN (ALPHA1 BETA1 INTEGRIN) 著者 Deivanayagam, C.C, Narayana, S.V. 登録日 1999-05-17 公開日 2000-05-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM. J.Biol.Chem., 274, 1999
3RAG	Crystal Structure of Uncharacterized protein Aaci_0196 from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 分子名称: GLYCEROL, SODIUM ION, uncharacterized protein 著者 Wu, R, Bedearn, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-03-28 公開日 2011-09-14 最終更新日 2011-12-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Uncharacterized protein Aaci_0196 from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 To be Published
6SNK	Crystal structure of the Collagen VI alpha3 N2 domain 分子名称: Collagen alpha-3(VI) chain 著者 Gebauer, J.M, Degefa, H.S, Paulsson, M, Wagener, R, Baumann, U. 登録日 2019-08-26 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a collagen VI alpha 3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations. J.Biol.Chem., 295, 2020
4XW2	Structural basis for simvastatin competitive antagonism of complement receptor 3 分子名称: Integrin alpha-M, MAGNESIUM ION, Simvastatin acid 著者 Bajic, G, Jensen, M.R, Vorup-Jensen, T, Andersen, G.R. 登録日 2015-01-28 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3. J.Biol.Chem., 291, 2016
4RCK	Crystal Structure of Uncharacterized Membrane Spanning Protein from Vibrio fischeri 分子名称: Hypothetical membrane spanning protein, MAGNESIUM ION 著者 Kim, Y, Tesar, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2014-09-16 公開日 2014-11-26 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Crystal Structure of Uncharacterized Membrane Spanning Protein from Vibrio fischeri To be Published
7A6O	Crystal Structure of the Complex of the Recombinant Von Willebrand Factor AIM-A1 domain and VHH81 at 2.1 Angstrom resolution 分子名称: SULFATE ION, VHH81 Nanobody fragment, von Willebrand factor 著者 Brown, A.K, Emsley, J. 登録日 2020-08-25 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.117 Å) 主引用文献 Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module. Nat Commun, 12, 2021
3M6F	CD11A I-domain complexed with 6-((5S,9R)-9-(4-CYANOPHENYL)-3-(3,5-DICHLOROPHENYL)-1-METHYL-2,4-DIOXO-1,3,7- TRIAZASPIRO[4.4]NON-7-YL)NICOTINIC ACID 分子名称: 6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl]pyridine-3-carboxylic acid, Integrin alpha-L, NITRATE ION 著者 Sheriff, S. 登録日 2010-03-15 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521). J.Med.Chem., 53, 2010
2B2X	VLA1 RdeltaH I-domain complexed with a quadruple mutant of the AQC2 Fab 分子名称: Antibody AQC2 Fab, Integrin alpha-1, MAGNESIUM ION 著者 Clark, L.A, Boriack-Sjodin, P.A, Eldredge, J, Fitch, C, Friedman, B, Hanf, K.J, Jarpe, M, Liparoto, S.F, Li, Y, Lugovskoy, A. 登録日 2005-09-19 公開日 2006-04-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design Protein Sci., 15, 2006
8CE6	Crystal structure of human Cd11b I domain in P212121 space group 分子名称: CHLORIDE ION, GLYCEROL, Integrin alpha-M, ... 著者 Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K. 登録日 2023-02-01 公開日 2023-03-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.582 Å) 主引用文献 Crystal structure of human Cd11b I domain in P212121 space group To Be Published
8CE9	Crystal structure of human Cd11b I domain in C121 space group 分子名称: 1,2-ETHANEDIOL, Integrin alpha-M, SULFATE ION 著者 Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K. 登録日 2023-02-01 公開日 2023-03-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal structure of human Cd11b I domain in C121 space group To Be Published
4CN8	Structure of proximal thread matrix protein 1 (PTMP1) from the mussel byssus 分子名称: 1,2-ETHANEDIOL, PROXIMAL THREAD MATRIX PROTEIN 1, SULFATE ION 著者 Gertz, M, Suhre, M.H, Scheibel, T, Steegborn, C. 登録日 2014-01-21 公開日 2014-03-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural and Functional Features of a Collagen-Binding Matrix Protein from the Mussel Byssus. Nat.Commun., 5, 2014
4CNB	Structure of proximal thread matrix protein 1 (PTMP1) from the mussel byssus - Crystal form 2 分子名称: 1,2-ETHANEDIOL, PROXIMAL THREAD MATRIX PROTEIN 1, SULFATE ION 著者 Gertz, M, Suhre, M.H, Scheibel, T, Steegborn, C. 登録日 2014-01-21 公開日 2014-03-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and Functional Features of a Collagen-Binding Matrix Protein from the Mussel Byssus. Nat.Commun., 5, 2014
6ADR	Anthrax Toxin Receptor 1-bound the Seneca Valley Virus in neutral conditions 分子名称: Anthrax toxin receptor 1, MAGNESIUM ION, VP1, ... 著者 Lou, Z.Y, Cao, L. 登録日 2018-08-02 公開日 2019-02-06 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1 Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2ICA	CD11a (LFA1) I-domain complexed with BMS-587101 aka 5-[(5S, 9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro [4.4]non-7-yl]methyl]-3-thiophenecarboxylicacid 分子名称: 5-[(5S,9R)-9-(4-CYANOPHENYL)-3-(3,5-DICHLOROPHENYL)-1-METHYL-2,4-DIOXO-1,3,7-TRIAZASPIRO [4.4]NON-7-YL]METHYL]-3-THIOPHENECARBOXYLICACID, Integrin alpha-L 著者 Sheriff, S, Einspahr, H. 登録日 2006-09-12 公開日 2006-12-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Discovery and Development of 5-[(5S,9R)-9- (4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1- methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non- 7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)-A Small Molecule Antagonist Leukocyte Function Associated Antigen-1. J.Med.Chem., 49, 2006
3BQN	LFA-1 I domain bound to inhibitors 分子名称: 4-{(2E)-3-[4-{[2-(pyridin-3-ylmethoxy)phenyl]sulfanyl}-2,3-bis(trifluoromethyl)phenyl]prop-2-enoyl}morpholine, Integrin alpha-L 著者 Silvian, L.F. 登録日 2007-12-20 公開日 2008-08-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors Bioorg.Med.Chem.Lett., 18, 2008
3BQM	LFA-1 I domain bound to inhibitors 分子名称: 3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline, Integrin alpha-L 著者 Silvian, L.F. 登録日 2007-12-20 公開日 2008-08-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Design and synthesis of a series of meta aniline-based LFA-1 ICAM inhibitors Bioorg.Med.Chem.Lett., 18, 2008
3TVY	Structural Analysis of Adhesive Tip pilin, GBS104 from Group B Streptococcus agalactiae 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cell wall surface anchor family protein, MAGNESIUM ION 著者 Krishnan, V, Narayana, S.V.L. 登録日 2011-09-21 公開日 2013-03-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions. Acta Crystallogr.,Sect.D, 69, 2013
3TW0	Structural Analysis of Adhesive Tip pilin, GBS104 from Group B Streptococcus agalactiae 分子名称: ACETATE ION, Cell wall surface anchor family protein, MAGNESIUM ION 著者 Krishnan, V, Narayana, S.V.L. 登録日 2011-09-21 公開日 2013-03-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions. Acta Crystallogr.,Sect.D, 69, 2013
4F1J	Crystal structure of the MG2+ loaded VWA domain of plasmodium falciparum trap protein 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Pihlajamaa, T, Knuuti, J, Kajander, T, Sharma, A, Permi, P. 登録日 2012-05-07 公開日 2013-01-30 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structure of Plasmodium falciparum TRAP (thrombospondin-related anonymous protein) A domain highlights distinct features in apicomplexan von Willebrand factor A homologues. Biochem.J., 450, 2013
5HGJ	Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition 分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ... 著者 Brown, K.L, Banerjee, S, Feigley, A, Abe, H, Blackwell, T, Zent, R, Pozzi, A, Hudson, B.H. 登録日 2016-01-08 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains. Sci Rep, 8, 2018
5HJ2	Integrin alpha2beta1 I-domain 分子名称: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Brown, K.L, Banerjee, S. 登録日 2016-01-12 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains. Sci Rep, 8, 2018
4DMU	Crystal structure of the von Willebrand factor A3 domain in complex with a collagen III derived triple-helical peptide 分子名称: Collagen III derived triple-helical peptide, SULFATE ION, von Willebrand factor 著者 Brondijk, T.H.C, Huizinga, E.G. 登録日 2012-02-08 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex. Proc.Natl.Acad.Sci.USA, 109, 2012
4CN9	structure of proximal thread matrix protein 1 (PTMP1) from the mussel byssus with zinc occupied MIDAS motif 分子名称: 1,2-ETHANEDIOL, GLYCEROL, PROXIMAL THREAD MATRIX PROTEIN 1, ... 著者 Gertz, M, Suhre, M.H, Scheibel, T, Steegborn, C. 登録日 2014-01-21 公開日 2014-03-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Functional Features of a Collagen-Binding Matrix Protein from the Mussel Byssus. Nat.Commun., 5, 2014
4F1K	Crystal structure of the MG2+ free VWA domain of plasmodium falciparum trap protein 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... 著者 Pihlajamaa, T, Knuuti, J, Kajander, T, Sharma, A, Permi, P. 登録日 2012-05-07 公開日 2013-01-30 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structure of Plasmodium falciparum TRAP (thrombospondin-related anonymous protein) A domain highlights distinct features in apicomplexan von Willebrand factor A homologues. Biochem.J., 450, 2013
3E2M	LFA-1 I domain bound to inhibitors 分子名称: Integrin alpha-L, cis-4-{[2-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)phenoxy]methyl}cyclohexanecarboxylic acid 著者 Silvian, L.F. 登録日 2008-08-05 公開日 2008-08-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors Bioorg.Med.Chem.Lett., 18, 2008

 

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