Functional Information from PROSITE/UniProt
| site_id | PS00077 |
| Number of Residues | 55 |
| Details | COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WWTGHPiVyfwllpayaiiytilpkqaggklvsdpmarlafllflllstpvgf..HH |
| Chain | Residue | Details |
| A | TRP229-HIS283 | |
| site_id | PS00078 |
| Number of Residues | 49 |
| Details | COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. ViHgfhvegtninvevlpgevstvrytfkrpgeyrii......CnqyCglgHqnM |
| Chain | Residue | Details |
| B | VAL112-MET160 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 260 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"1'-histidyl-3'-tyrosine (His-Tyr)"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 64 |
| Details | Transmembrane: {"description":"Helical"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 129 |
| Details | Topological domain: {"description":"Periplasmic"} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 735 |
| Chain | Residue | Details |
| B | PHE86 | electron shuttle |
| B | PHE88 | electron shuttle |
| A | HIS384 | electron shuttle |
| A | PHE385 | electron shuttle |
| A | HIS386 | electron shuttle |
| A | ARG449 | electron shuttle |
| A | ARG450 | electron shuttle |
9VDJ
