9R3S
pro-TGF-beta1 in complex with the third TB Domain from Latent Transforming Growth Factor-beta Binding Protein-1
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. ClNtrpgYeCyC |
| Chain | Residue | Details |
| C | CYS1441-CYS1452 | |
| C | CYS1482-CYS1493 | |
| C | CYS1681-CYS1692 |
| site_id | PS00250 |
| Number of Residues | 16 |
| Details | TGF_BETA_1 TGF-beta family signature. IhePkgYhanfClGpC |
| Chain | Residue | Details |
| B | ILE311-CYS326 |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CdCfdGYhldtakmtC |
| Chain | Residue | Details |
| C | CYS1645-CYS1660 | |
| C | CYS1690-CYS1705 |
| site_id | PS01187 |
| Number of Residues | 27 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DaDECllfgqei.......Ckngf...ClNtrpgYeC |
| Chain | Residue | Details |
| C | ASP1424-CYS1450 | |
| C | ASP1467-CYS1491 | |
| C | ASP1662-CYS1690 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 44 |
| Details | Region: {"description":"Straightjacket domain","evidences":[{"source":"UniProtKB","id":"P07200","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16263699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FFO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 54 |
| Details | Domain: {"description":"TB 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00697","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000184","evidences":[{"source":"PubMed","id":"10677208","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8617200","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
